DIABETES PREVENTION PROGRAM OUTCOMES STUDY (DPPOS)

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 DPPOS是一项全国性的临床试验，研究通过饮食和运动减肥或糖尿病药物二甲双胍是否可以继续预防或推迟参加糖尿病预防计划的高危志愿者的2型糖尿病。假设这些干预措施将导致以前的DPP干预组与以前的安慰剂组相比糖尿病发病率更低；预防或推迟糖尿病将导致更好的健康和减少糖尿病并发症。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DPPOS is a nationwide clinical trial studying whether weight loss through diet and exercise or the diabetes medication metformin can continue to prevent or delay type 2 diabetes in high-risk volunteers who participated in the Diabetes Prevention Program. The hypotheses are that these interventions will result in lower rates of diabetes in former DPP intervention groups compared with the former placebo group; and preventing or delaying diabetes will lead to better health and a reduction in diabetes complications.