CLINICAL TRIAL: DIABETES PREVENTION PROGRAM OUTCOMES STUDY (DPPOS)

临床试验：糖尿病预防计划结果研究 (DPPOS)

• 批准号: 7731238
• 负责人: DAVID M NATHAN
• 金额: $ 0.1万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731238
• 关键词: Body Weight decreased; Clinical Trials; Complications of Diabetes Mellitus; Computer Retrieval of Information on Scientific Projects Database; Diabetes Mellitus; Funding; Grant; Health; Institution; Intervention; Lead; Metformin; Non-Insulin-Dependent Diabetes Mellitus; Outcome Study; Pharmaceutical Preparations; Placebos; Rate; Research; Research Personnel; Resources; Risk; Source; United States National Institutes of Health; diabetes prevention program; diet and exercise; prevent; volunteer

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DPPOS is a nationwide clinical trial studying whether weight loss through diet and exercise or the diabetes medication metformin can continue to prevent or delay type 2 diabetes in high-risk volunteers who participated in the Diabetes Prevention Program. The hypotheses are that these interventions will result in lower rates of diabetes in former DPP intervention groups compared with the former placebo group; and preventing or delaying diabetes will lead to better health and a reduction in diabetes complications.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 DPPOS是一项全国性的临床试验，研究通过饮食和运动减肥或糖尿病药物二甲双胍是否可以继续预防或延迟参加糖尿病预防计划的高风险志愿者的2型糖尿病。假设这些干预措施将导致前DPP干预组的糖尿病发病率低于前安慰剂组;预防或延迟糖尿病将导致更好的健康和糖尿病并发症的减少。