Training Program in Investigative Hematology

描述(由申请人提供)： 斯坦福大学血液科的两个主要研究方向是恶性血液学和血管生物学。这既涉及基础研究，也涉及临床研究。这里描述的计划将为学术血液学的职业生涯培养博士后研究员。完成内科培训的拥有医学博士或医学博士学位的候选人将被录取参加这个为期三年的项目。该计划的第一年包括临床血液学的强化培训，包括良性和恶性血液学、干细胞和骨髓移植以及输血医学。在第二年和第三年，学员将把大部分时间用于研究性学习。这将在基础科学家路径或临床研究人员路径中完成。基础-科学家之路主要面向有丰富基础研究经验的学员，重点是恶性血液学、血管生物学和相关基础研究领域。临床研究人员路径提供临床研究方面的正式培训，并在Julie Parsonnet博士的指导下纳入斯坦福大学的K30临床研究人员培训计划，从而在完成正式培训后获得硕士学位。除了授课培训外，临床研究人员路径研究员还将在血液科进行实践临床试验。在这项资助申请中，要求为二年级和三年级的研究培训提供助学金。通常需要三年以上的培训。我们鼓励学员在第四年申请并获得他们自己的独立指导研究培训支持。对于每个研究员，研究培训将由血液科的一名全职教员或斯坦福大学代表血液学培训相关学科的多名副教员中的一名负责监督。这些院系包括生物化学、分子药理学、微生物学、免疫学、病理学、内科肿瘤学、骨髓移植、心脏病学、儿科学、流行病学、结果研究和卫生政策。指导委员会将定期与每个研究员会面，每个研究员的进展将由计划主任和培训计划指导委员会审查。培训结束后，学员将作为一名科学和血液学前沿的独立研究员，为学术血液学的职业生涯做好准备。(摘要结束)

DESCRIPTION (provided by applicant): The two major research directions for the Division of Hematology at Stanford are malignant hematology and vascular biology. This involves both basic and clinical research. The program described herein will train postdoctoral fellows for a career in academic hematology. Candidates with MD or MD/PhD degrees who have completed training in Internal Medicine will be admitted to the three-year program. The first year of the program consists of an intensive training in clinical hematology, including benign and malignant hematology, stem cell and bone marrow transplantation, and transfusion medicine. In Year 2 and Year 3, the trainees will devote the majority o their time to research-based study. This will be done in a Basic-Scientist Pathway or a Clinical Investigator Pathway. The Basic-Scientist Pathway is primarily for trainees with substantial prior basic research experience, focusing on malignant hematology, vascular biology, and related basic research areas. The Clinical Investigator Pathway provides formal training in clinical research and incorporates the K30 clinical Investigator Training program at Stanford under the direction of Dr. Julie Parsonnet, leading to a Master's degree at the completion of formal training. In addition to the didactic training, the Clinical Investigator Pathway fellow will also conduct hands-on clinical trials in the Division of Hematology. Fellow stipend support for the research training in Year 2 and Year 3 is requested in this grant application. More than three years of training is often required. Trainees are encouraged to apply for and obtain their own independent mentored research training support in Year 4. For each fellow, the research training will be supervised by a full-time faculty member in the Division of Hematology, or one of a number of associate faculty members at Stanford University, representing disciplines relevant to hematology training. These include faculty in biochemistry, molecular pharmacology, microbiology, immunology, pathology, medical oncology, bone marrow transplantation, cardiology, pediatrics, epidemiology, outcome research, and health policy. A mentoring committee will meet regularly with each fellow, and the progress of each fellow will be reviewed by the Program Director and the Training Program Steering Committee. At the conclusion of their training, trainees will be prepared for a career in academic hematology, as an independent investigator at the forefront of science and hematology. (End of Abstract)