Training Program in Investigative Hematology

描述（由申请人提供）： 斯坦福大学血液学系的两个主要研究方向是恶性血液学和血管生物学。这涉及基础和临床研究。本文所述的计划将培养博士后研究员在学术血液学的职业生涯。已完成内科培训的MD或MD/PhD学位候选人将被录取为三年制课程。该计划的第一年包括临床血液学的强化培训，包括良性和恶性血液学，干细胞和骨髓移植以及输血医学。在第二年和第三年，学员将把大部分时间用于研究性学习。这将在基础科学家途径或临床研究者途径中完成。基础科学家途径主要面向具有丰富基础研究经验的学员，重点是恶性血液学，血管生物学和相关基础研究领域。临床研究者途径提供临床研究的正式培训，并在Julie Parsonnet博士的指导下在斯坦福大学纳入K30临床研究者培训计划，在完成正式培训后获得硕士学位。除了教学培训外，临床研究者途径研究员还将在血液学部门进行实践临床试验。研究员助学金支持在第二年和第三年的研究培训要求在此补助金申请。通常需要三年以上的培训。鼓励学员申请并在第四年获得自己的独立指导研究培训支持。对于每名研究员，研究培训将由血液学系的一名全职教员或斯坦福大学代表血液学培训相关学科的多名副教员之一监督。这些包括生物化学，分子药理学，微生物学，免疫学，病理学，医学肿瘤学，骨髓移植，心脏病学，儿科学，流行病学，结果研究和卫生政策的教师。指导委员会将定期与每个研究员会面，每个研究员的进展将由项目主任和培训项目指导委员会审查。在培训结束时，学员将为学术血液学的职业生涯做好准备，作为科学和血液学前沿的独立调查员。(End摘要）

DESCRIPTION (provided by applicant): The two major research directions for the Division of Hematology at Stanford are malignant hematology and vascular biology. This involves both basic and clinical research. The program described herein will train postdoctoral fellows for a career in academic hematology. Candidates with MD or MD/PhD degrees who have completed training in Internal Medicine will be admitted to the three-year program. The first year of the program consists of an intensive training in clinical hematology, including benign and malignant hematology, stem cell and bone marrow transplantation, and transfusion medicine. In Year 2 and Year 3, the trainees will devote the majority o their time to research-based study. This will be done in a Basic-Scientist Pathway or a Clinical Investigator Pathway. The Basic-Scientist Pathway is primarily for trainees with substantial prior basic research experience, focusing on malignant hematology, vascular biology, and related basic research areas. The Clinical Investigator Pathway provides formal training in clinical research and incorporates the K30 clinical Investigator Training program at Stanford under the direction of Dr. Julie Parsonnet, leading to a Master's degree at the completion of formal training. In addition to the didactic training, the Clinical Investigator Pathway fellow will also conduct hands-on clinical trials in the Division of Hematology. Fellow stipend support for the research training in Year 2 and Year 3 is requested in this grant application. More than three years of training is often required. Trainees are encouraged to apply for and obtain their own independent mentored research training support in Year 4. For each fellow, the research training will be supervised by a full-time faculty member in the Division of Hematology, or one of a number of associate faculty members at Stanford University, representing disciplines relevant to hematology training. These include faculty in biochemistry, molecular pharmacology, microbiology, immunology, pathology, medical oncology, bone marrow transplantation, cardiology, pediatrics, epidemiology, outcome research, and health policy. A mentoring committee will meet regularly with each fellow, and the progress of each fellow will be reviewed by the Program Director and the Training Program Steering Committee. At the conclusion of their training, trainees will be prepared for a career in academic hematology, as an independent investigator at the forefront of science and hematology. (End of Abstract)