Modulation of Vegfc/Vegfr3 signaling at the extracellular matrix during embryonic lymphangiogenesis
Modulation of Vegfc/Vegfr3 signaling at the extracellular matrix during embryonic lymphangiogenesis
批准号:
nhmrc : 1050138
负责人:
A/Pr Benjamin Hogan
金额:
$38.07万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31
中文摘要
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英文摘要
Lymphatic vessels play important roles in vascular diseases and cancer. However, we are yet to understand how they form during development and disease. We recently identified the gene CCBE1, essential for the formation of lymphatic vessels and responsible for lymphatic dysplasia in humans. This study aims to understand the molecular pathway in which CCBE1 acts. This work aims to characterize new molecular pathways in lymphatic vessels in order to identify new therapeutic targets in lymphatic disease and cancer.
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Mechanisms of vascular development in health and disease
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批准号:nhmrc : GNT1155221
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项目类别:Research Fellowships
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资助金额:$64.92万
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财政年份:2019
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负责人:A/Pr Benjamin Hogan
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依托单位:
Understanding the role of the atypical cadherin Fat4 in lymphatic vascular development
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批准号:nhmrc : 1146352
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项目类别:Project Grants
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资助金额:$67.1万
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财政年份:2018
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负责人:A/Pr Benjamin Hogan
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依托单位:
Understanding the role of the atypical cadherin Fat4 in lymphatic vascular development
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批准号:nhmrc : GNT1146352
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项目类别:Project Grants
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资助金额:$99.24万
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财政年份:2018
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负责人:A/Pr Benjamin Hogan
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依托单位:
Coupling the mechanical, signalling and transcriptional mechanisms that initiate pathogenesis of Cerebral Cavernous Malformation
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批准号:nhmrc : 1124011
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项目类别:Project Grants
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资助金额:$83.93万
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财政年份:2017
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负责人:A/Pr Benjamin Hogan
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依托单位:
Coupling the mechanical, signalling and transcriptional mechanisms that initiate pathogenesis of Cerebral Cavernous Malformation
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批准号:nhmrc : GNT1124011
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项目类别:Project Grants
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资助金额:$122.84万
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财政年份:2017
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负责人:A/Pr Benjamin Hogan
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依托单位:
Characterisation of a newly identified, indispensible, transcriptional regulator of lymphangiogenesis
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批准号:nhmrc : GNT1107755
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项目类别:Project Grants
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资助金额:$53.52万
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财政年份:2016
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负责人:A/Pr Benjamin Hogan
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依托单位:
Characterisation of a newly identified, indispensible, transcriptional regulator of lymphangiogenesis
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批准号:nhmrc : 1107755
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项目类别:Project Grants
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资助金额:$36.68万
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财政年份:2016
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负责人:A/Pr Benjamin Hogan
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依托单位:
A critical new signaling axis in lymphatic vascular angiogenesis
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批准号:nhmrc : 1079158
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项目类别:Project Grants
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资助金额:$46.73万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
Novel transcription factor regulation of lymphatic vascular angiogenesis in health and disease
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批准号:nhmrc : 1079670
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项目类别:Project Grants
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资助金额:$55.45万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
The genetic and cellular control of lymphangiogenesis in health and disease
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批准号:nhmrc : 1083811
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项目类别:Career Development Fellowships
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资助金额:$31.71万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
The genetic and cellular control of lymphangiogenesis in health and disease
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批准号:nhmrc : GNT1083811
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项目类别:Career Development Fellowships
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资助金额:$45.55万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
Novel transcription factor regulation of lymphatic vascular angiogenesis in health and disease
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批准号:nhmrc : GNT1079670
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项目类别:Project Grants
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资助金额:$80.01万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
Using high-throughput genomics to reveal the deleterious genetic changes that underlie paediatric leukoencephalopathies
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批准号:nhmrc : 1068278
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项目类别:Project Grants
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资助金额:$66.93万
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财政年份:2014
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负责人:A/Pr Benjamin Hogan
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依托单位:
Uncovering a novel genetic interaction that governs blood vessel development in health and disease
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批准号:nhmrc : 1048242
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项目类别:Project Grants
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资助金额:$41.78万
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财政年份:2013
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负责人:A/Pr Benjamin Hogan
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依托单位:
Functional and molecular characterization of a novel regulator of angiogenesis
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批准号:nhmrc : 1046028
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项目类别:Project Grants
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资助金额:$31.67万
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财政年份:2013
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负责人:A/Pr Benjamin Hogan
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依托单位:
Characterisation of conserved Sox18-dependent genes in lymphatic vascular development
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批准号:nhmrc : 1008586
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项目类别:NHMRC Project Grants
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资助金额:$26.76万
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财政年份:2011
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负责人:A/Pr Benjamin Hogan
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依托单位:
The mechanism of ccbe1 function during lymphangiogenesis
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批准号:nhmrc : 631657
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项目类别:NHMRC Project Grants
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资助金额:$33.5万
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财政年份:2010
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负责人:A/Pr Benjamin Hogan
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依托单位:
Genetic control of embryonic lymphangiogenesis
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批准号:nhmrc : 433628
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项目类别:Early Career Fellowships
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资助金额:$26.02万
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财政年份:2007
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负责人:A/Pr Benjamin Hogan
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依托单位:
国内基金
海外基金
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