Characterisation of a newly identified, indispensible, transcriptional regulator of lymphangiogenesis
Characterisation of a newly identified, indispensible, transcriptional regulator of lymphangiogenesis
批准号:
nhmrc : 1107755
负责人:
A/Pr Benjamin Hogan
金额:
$36.68万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31
来源:
中文摘要
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英文摘要
Lymphatic vessels form via lymphangiogenesis: growth of lymphatics from pre-existing vessels. This process is amenable to therapeutic intervention during metastasis because lymphatics support tumour spread. We discovered a gene that is essential for lymphangiogenesis to occur. We will investigate the control of lymphangiogenesis by this new factor. We aim to understand how it controls lymphatic vessel formation and identify genes within this pathway that have novel therapeutic potential.
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会议论文
Mechanisms of vascular development in health and disease
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批准号:nhmrc : GNT1155221
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项目类别:Research Fellowships
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资助金额:$64.92万
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财政年份:2019
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负责人:A/Pr Benjamin Hogan
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依托单位:
Understanding the role of the atypical cadherin Fat4 in lymphatic vascular development
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批准号:nhmrc : 1146352
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资助金额:$67.1万
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财政年份:2018
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负责人:A/Pr Benjamin Hogan
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依托单位:
Understanding the role of the atypical cadherin Fat4 in lymphatic vascular development
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批准号:nhmrc : GNT1146352
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项目类别:Project Grants
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资助金额:$99.24万
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财政年份:2018
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负责人:A/Pr Benjamin Hogan
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依托单位:
Coupling the mechanical, signalling and transcriptional mechanisms that initiate pathogenesis of Cerebral Cavernous Malformation
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批准号:nhmrc : 1124011
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项目类别:Project Grants
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资助金额:$83.93万
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财政年份:2017
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负责人:A/Pr Benjamin Hogan
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依托单位:
Coupling the mechanical, signalling and transcriptional mechanisms that initiate pathogenesis of Cerebral Cavernous Malformation
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批准号:nhmrc : GNT1124011
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项目类别:Project Grants
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资助金额:$122.84万
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财政年份:2017
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负责人:A/Pr Benjamin Hogan
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依托单位:
Characterisation of a newly identified, indispensible, transcriptional regulator of lymphangiogenesis
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批准号:nhmrc : GNT1107755
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项目类别:Project Grants
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资助金额:$53.52万
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财政年份:2016
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负责人:A/Pr Benjamin Hogan
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依托单位:
A critical new signaling axis in lymphatic vascular angiogenesis
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批准号:nhmrc : 1079158
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项目类别:Project Grants
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资助金额:$46.73万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
Novel transcription factor regulation of lymphatic vascular angiogenesis in health and disease
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批准号:nhmrc : 1079670
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项目类别:Project Grants
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资助金额:$55.45万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
The genetic and cellular control of lymphangiogenesis in health and disease
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批准号:nhmrc : 1083811
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项目类别:Career Development Fellowships
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资助金额:$31.71万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
The genetic and cellular control of lymphangiogenesis in health and disease
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批准号:nhmrc : GNT1083811
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项目类别:Career Development Fellowships
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资助金额:$45.55万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
Novel transcription factor regulation of lymphatic vascular angiogenesis in health and disease
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批准号:nhmrc : GNT1079670
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项目类别:Project Grants
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资助金额:$80.01万
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财政年份:2015
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负责人:A/Pr Benjamin Hogan
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依托单位:
Using high-throughput genomics to reveal the deleterious genetic changes that underlie paediatric leukoencephalopathies
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批准号:nhmrc : 1068278
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项目类别:Project Grants
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资助金额:$66.93万
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财政年份:2014
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负责人:A/Pr Benjamin Hogan
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依托单位:
Uncovering a novel genetic interaction that governs blood vessel development in health and disease
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批准号:nhmrc : 1048242
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项目类别:Project Grants
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资助金额:$41.78万
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财政年份:2013
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负责人:A/Pr Benjamin Hogan
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依托单位:
Modulation of Vegfc/Vegfr3 signaling at the extracellular matrix during embryonic lymphangiogenesis
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批准号:nhmrc : 1050138
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项目类别:Project Grants
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资助金额:$38.07万
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财政年份:2013
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负责人:A/Pr Benjamin Hogan
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依托单位:
Functional and molecular characterization of a novel regulator of angiogenesis
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批准号:nhmrc : 1046028
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项目类别:Project Grants
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资助金额:$31.67万
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财政年份:2013
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负责人:A/Pr Benjamin Hogan
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依托单位:
Characterisation of conserved Sox18-dependent genes in lymphatic vascular development
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批准号:nhmrc : 1008586
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项目类别:NHMRC Project Grants
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资助金额:$26.76万
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财政年份:2011
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负责人:A/Pr Benjamin Hogan
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依托单位:
The mechanism of ccbe1 function during lymphangiogenesis
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批准号:nhmrc : 631657
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项目类别:NHMRC Project Grants
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资助金额:$33.5万
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财政年份:2010
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负责人:A/Pr Benjamin Hogan
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依托单位:
Genetic control of embryonic lymphangiogenesis
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批准号:nhmrc : 433628
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项目类别:Early Career Fellowships
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资助金额:$26.02万
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财政年份:2007
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负责人:A/Pr Benjamin Hogan
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依托单位:
海外基金