Mechanisms of vascular development in health and disease

健康和疾病中血管发育的机制

• 批准号: nhmrc : GNT1155221
• 负责人: A/Pr Benjamin Hogan
• 金额: $ 64.92万
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanisms-vascular-development-health-disease/1349183
• 关键词: Mechanisms; vascular; development; health; disease

Excessive or inadequate formation of vasculature can contributes to diseases including lymphoedema, lymphangioma, cancer, ischaemia, ocular disease, cardiovascular disease and inflammation. Hence, we need to be able to manipulate vessel formation with molecular approaches. This program will use cutting edge methodologies to discover new molecular pathways that control vessel formation. The new knowledge generated will open up avenues to control vascular pathologies in the future.

脉管系统的过度或不充分形成可导致包括淋巴水肿、淋巴管瘤、癌症、局部缺血、眼部疾病、心血管疾病和炎症的疾病。因此，我们需要能够用分子方法操纵血管形成。该计划将使用最先进的方法来发现控制血管形成的新分子途径。所产生的新知识将在未来开辟控制血管病变的途径。