Molecular analysis of mouse NKT cell receptors

小鼠 NKT 细胞受体的分子分析

• 批准号: nhmrc : 566747
• 负责人: Dr Hugh Reid
• 金额: $ 35.32万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-analysis-mouse-cell-receptors/95895
• 关键词: Molecular; analysis; mouse; NKT; cell

NKT cells are a type of lymphocyte with the ability to prevent a broad range of diseases including cancer, autoimmunity, infection and graft rejection. Sometimes, NKT cells also cause diseases, including allergy and atherosclerosis. Therefore, the ability to modulate these cells an important health objective. This project will investigate how NKT cells become activated by studying their surface receptors and what these receptors interact with.

NKT细胞是一种淋巴细胞，具有预防多种疾病的能力，包括癌症、自身免疫、感染和移植物排斥反应。有时，NKT细胞也会引起疾病，包括过敏和动脉粥样硬化。因此，调节这些细胞的能力是一个重要的健康目标。这个项目将通过研究NKT细胞的表面受体以及这些受体与什么相互作用来研究NKT细胞是如何激活的。