A PHASE II/III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF URIDINE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究将试图了解服用尿苷补充剂(NucleomaxX)对艾滋病毒感染者是否安全，以及它是否可以逆转面部、手臂、腿部或臀部的脂肪流失。这项研究还将试图观察NucleomaxX的耐受性有多好。Nucleomax X是一种粉状营养食品补充剂，含有一种名为尿苷的物质。它是装在香包里的，需要和果汁、牛奶或水混合。NucleomaxX在欧洲被用作食品补充剂，但没有得到美国食品和药物管理局(FDA)的批准，在美国被认为是一种实验性药物。大约164人将参与这项研究。南加州大学将尝试招收10门学科。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will try to see if taking a uridine supplement (NucleomaxX¿) is safe in HIV-infected persons and if it will reverse loss of fat in the face, arms, legs, or buttocks. The study will also try to see how well NucleomaxX is tolerated. NucleomaxX is a powdered nutritional food supplement that contains a substance called uridine. It comes in a sachet (packet) and needs to be mixed in with juice, milk, or water. NucleomaxX is used in Europe as a food supplement but is not approved by the U.S. Food and Drug Administration (FDA) and is considered an experimental drug in the U.S. About 164 people will take part in this study. USC will attempt to enroll 10 subjects.