A PHASE II/III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF URIDINE

尿苷 II/III 期、随机、双盲、安慰剂对照试验

• 批准号: 7982124
• 负责人: FRED R SATTLER
• 金额: $ 4.16万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7982124
• 关键词: Buttocks; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Enrollment; Europe; Face; Fatty acid glycerol esters; Food Supplements; Funding; Grant; Institution; Juice; Leg; Milk; Nutritional; Persons; Pharmaceutical Preparations; Phase; Powder dose form; Randomized; Research; Research Personnel; Resources; Source; United States Food and Drug Administration; United States National Institutes of Health; Upper arm; Uridine; Water; double-blind placebo controlled trial

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will try to see if taking a uridine supplement (NucleomaxX¿) is safe in HIV-infected persons and if it will reverse loss of fat in the face, arms, legs, or buttocks. The study will also try to see how well NucleomaxX is tolerated. NucleomaxX is a powdered nutritional food supplement that contains a substance called uridine. It comes in a sachet (packet) and needs to be mixed in with juice, milk, or water. NucleomaxX is used in Europe as a food supplement but is not approved by the U.S. Food and Drug Administration (FDA) and is considered an experimental drug in the U.S. About 164 people will take part in this study. USC will attempt to enroll 10 subjects.

该副本是使用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这是调查员的机构。 这项研究将尝试查看接受尿苷补充剂（Nucleomaxx®）是否在感染HIV的人中是安全的，并且是否会逆转面部，手臂，腿部或臀部的脂肪损失。该研究还将尝试了解核敏量的耐受性如何。 NucleOmaxx是一种粉状的营养食品补充剂，其中含有一种称为尿苷的物质。它装在小袋中（小包），需要与果汁，牛奶或水混合。 Nucleomaxx在欧洲用作食品补充剂，但未获得美国食品药品监督管理局（FDA）的批准，在美国被认为是一种实验性药物，将参加这项研究。南加州大学将尝试注册10个主题。