THE ROLE OF FSH IN HUMAN GONADAL DEVELOPMENT

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall goal of this study is to better understand the role follicle stimulating hormone (FSH) in reproductive development. A specific purpose of this study is to develop a treatment for infertility for men with severe cases of hypogonadism. FSH therapy followed by pulsatile GnRH therapy is compared to pulsatile GnRH therapy alone. Measuring hormone levels, testicular development, and fertility are the ways we measure successful outcomes in this study.