Developmental

发育性

• 批准号: 8335532
• 负责人: MICHAEL V. SEIDEN
• 金额: $ 34.54万
• 依托单位: FOX CHASE CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-21 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8335532
• 关键词: Address; Appointment; Area; Bioinformatics; Cancer Center; Cancer Center Support Grant; Clinical Investigator; Collaborations; Comprehensive Cancer Center; Development; Emerging Technologies; Epigenetic Process; Evaluation; Exclusion; Faculty; Foundations; Fox Chase Cancer Center; Foxes; Funding; Genomics; Grant; Growth; Informatics; Institutes; Instruction; Investigation; Laboratories; Medicine; Methodology; Mission; Peer Review; Pilot Projects; Positioning Attribute; Publications; Recruitment Activity; Research Personnel; Research Priority; Scientist; Strategic Planning; Technology; Translational Research; anticancer research; cost; high throughput screening; innovation; new technology; programs; technology development

PROJECT SUMMARY (See instructions): Developmental funds are requested to recruit faculty level scientists in areas of strategic need, to support pilot projects that allow Fox Chase Cancer Center scientists to pursue innovative ideas in high priority research areas, and to support technology and methodology development projects related to the Center's discovery mission and strategic objectives. In the past CCSG cycle, 40 investigators were recruited and, with the exclusion of our 17 newest recruits, 19 of 23 (83%) have obtained $15.4 million in peer reviewed funding within 24 months of their appointment Of that amount $5.1 million was garnered by investigators directly leveraging developmental funds. Also, this class competed successfully for a further $1.6 million in competitive foundation support. During the last CCSG cycle, pilot project funds were utilized in the second, fifth and sixth years to support potential high-impact projects, largely from established investigators. The 12 funded projects have already produced two funded grants and seven publications. During the past CCSG cycle, the Center provided start up support for a High Throughput Screening Facility that has become one of the 16 established shared facilities. In the present CCSG application we seek partial support for the 25 new investigators identified as necessary to address the critical mass needs of the Center's five existing programs over the next CCSG cycle. This request represents less than 25% of the average cost of supporting a new investigator. We also seek support for partial funding for four translational pilot projects per year. These CCSG funds will be matched by institutional funds. Finally, we seek partial funding for technology developments and informatics initiatives in support of the Center's Institute for Personalized Medicine. All of these developmental funds are considered vital to achieving the discovery objectives outlined in the Center's Strategic Plan.

项目摘要（请参阅说明）： 要求发展基金在战略需求领域招募教师级别的科学家，以支持允许Fox Chase Cance Cancer Center科学家在高优先研究领域中追求创新思想的试点项目，并支持与该中心的发现任务和战略目标相关的技术和方法论开发项目。在过去的CCSG周期中，招募了40名调查员 而且，由于我们的17名最新新兵排除了，其中23名（83％）中有19名（83％）在任命这笔510万美元的24个月内获得了1540万美元的同行审查资金。此外，该班级成功获得了160万美元的竞争基础支持。在上一个CCSG周期中，使用了试点项目资金 在第二，第五和六年中，支持潜在的高影响力项目，这主要来自既定的研究人员。这12个资助的项目已经生产了两个资助的赠款和7个出版物。 在过去的CCSG周期中，该中心为高通量筛查设施提供了启动支持，该设施已成为已建立的共享设施之一。 在当前的CCSG应用程序中，我们寻求对25位新调查人员的部分支持，这些新调查人员在下一个CCSG周期中确定了该中心现有五个计划的关键质量需求所必需的必要条件。该请求不到支持新调查员的平均成本的25％。我们还为每年四个转化试点项目寻求部分资金。这些CCSG资金将是 由机构资金匹配。最后，我们寻求针对技术发展和信息学计划的部分资金，以支持该中心的个性化医学研究所。所有这些发展基金对于实现中心战略计划中概述的发现目标至关重要。