HISTOLOGY/IMAGING CORE FACILITY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 组织学和成像核心将设在南卡罗来纳大学医学院仪器资源设施(IRF)，这是一个现有的核心设施，服务于整个南加州大学的研究环境。与目前的科布雷基金一样，组织学和成像学的目的是： A)提供使用最先进的昂贵仪器的途径； B)提供有效操作设备的专门知识； C)协助解释核心为准备实验、赠款和出版物而产生的数据。 作为CCCR Cobre的核心资源，CCCR Cobre有三个主要目标：1)通过生物技术核心预算为CCCR Cobre目标学院提供使用IRF中的所有设备和技术专长的机会，这样目标研究人员就不会支付IRF的使用费；2)为与研究人员的合作提供更好的沟通渠道 为初级和高级CCCR Cobre调查人员提供的IRF；3)为整个南卡罗来纳大学的研究环境提供改进的基础设施能力。 在现有Cobre赠款的头四年里，Core与CCCR Cobre的大多数初级和高级教职员工进行了互动。所有初级调查人员，包括目标学院和新雇用的人员，都通过组织学和成像核心预算向IRF补偿，免费使用了IRF的设备和技术人员。虽然目前科布雷初级和高级调查人员约占IRF总使用量的30%，但该设施拥有庞大而多样化的用户基础，其中包括来自南卡罗来纳大学内多所学院的调查人员。多样化的用户群体，加上医学院的财政支持(目前为300,000美元/年)，确保了COBRE第二个五年期结束后核心的持续生存能力。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Histology and Imaging Core will be housed in the University of South Carolina School of Medicine Instrumentation Resource Facilty (IRF) which is an existing core facility serving the entire USC research environment. As in the current COBRE grant, the purpose of the Histology and Imaging is to: A) provide access to state-of-the-art expensive instrumentation; B) Provide the expertise to efficiently operate the equipment; C) to provide assistance in the interpretation of data generated in the Core for the preparation of experiments, grants and publications. As a core resource for the CCCR COBRE there are three primary goals: 1) to provide access to all equipment and technical expertise in the IRF for CCCR COBRE Target Faculty through the Biotechnology Core budget so that no Target Investigators will pay IRF user fees; 2) to provide an improved avenue of communication for collaborations with research faculty within the IRF for Junior and Senior CCCR COBRE Investigators; and 3) to provide improved infrastructure capabilities for the entire University of South Carolina research environment. During the first four years of the existing COBRE grant the Core has interacted with most junior and senior faculty members affiliated with the CCCR COBRE. All Junior Investigators, including Target Faculty as well as new hires, have received free use of the IRF equipment and technicians through compensation to the IRF by the Histology and Imaging Core budget. Although the current group of COBRE Junior and Senior investigators represent approximately 30% of the total use of the IRF, the facility has a large and diverse user base that includes investigators from a number of colleges within the University of South Carolina. The diverse group of users, along with financial support from the School of Medicine (currently $300,000/year) insures the continued viability of the Core after the completion of the second five year period of the COBRE.