Southern California Network Clinical Center (Hub) for SIREN Emergency Care Clinical Trails

SIREN 紧急护理临床试验南加州网络临床中心(中心)

基本信息

  • 批准号:
    9284308
  • 负责人:
  • 金额:
    $ 25.71万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-07-15 至 2022-05-31
  • 项目状态:
    已结题

项目摘要

Medical and traumatic emergency conditions affecting the cardiac, respiratory, nervous, and hematologic systems collectively account for the overwhelming preponderance of death and disability affecting Americans. It is imperative that new approaches for timely diagnosis and treatment of these conditions treatments be efficiently developed. This application is to form a Southern California Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SoCal SIREN) Hub and Spoke system that will conduct high-quality, multi-site clinical trials to improve the outcomes for patients with neurologic, cardiac, respiratory, and hematologic, and trauma emergency events. The SoCal SIREN consortium will marshal all six academic medical centers in the region (UCLA, Harbor-UCLA, USC, UCI, UCSD, and Cedars-Sinai); all 3 County EMS agencies [Los Angeles EMS (lead), Orange County EMS (co-lead), and San Diego County EMS (flexible)], and up to 83 potential performance sites (1 Hub, 5 Core Spoke, 16 Additional Spoke, and 61 Flexible Spoke) Medical Centers in Southern California, experienced in performing emergency clinical trials efficiently and excellently. Eleven Advisory Panels with expertise in specific disease and research domains will facilitate trial implementation within the Network and serve as a resource to the Hub leadership and to individual performance sites. The four specific aims of this proposal are to: 1) perform high-quality pragmatic clinical trials in several different types of emergency disorders afflicting adults or children throughout Southern California; 2) facilitate collaboration between emergency medicine physicians and disease specialists throughout Southern California in trial design and execution high quality NSTN recovery and rehabilitaiton trials throughout Los Angeles and Orange Counties; 3) facilitate collaboration between the prehospital EMS system and acute receiving hospitals, including specialty receiving centers in trauma, stroke, and cardiac resuscitation, throughout Southern California in trial design and execution; and 4) ensure participation of a substantial number of patients with emergency conditions in SIREN clinical trials, including women, children, Hispanic-Americans, African-Americans, and other traditionally underrepresented populations.
影响心脏、呼吸、神经和血液系统的医疗和创伤性紧急情况 总体而言,影响美国人的死亡和残疾占压倒性优势。当务之急是 应有效地开发及时诊断和治疗这些疾病治疗的新方法。 这项申请是为了形成南加州创新急诊护理临床试验的战略 网络(SoCal Siren)中心和辐条系统,将进行高质量的多点临床试验,以改善 神经系统、心脏、呼吸系统、血液系统和创伤急诊事件患者的预后。The SoCal Siren财团将组织该地区所有六个学术医疗中心(加州大学洛杉矶分校、港湾-加州大学洛杉矶分校、南加州大学、加州大学洛杉矶分校 UCSD和Cedars-Sinai);所有3个县EMS机构[洛杉矶EMS(牵头)、奥兰治县EMS(联合牵头)和旧金山 迭戈县EMS(灵活)]和多达83个潜在的性能站点(1个中枢、5个核心辐条、16个附加辐条和 61个柔性辐条)位于南加州的医疗中心,在进行紧急临床试验方面经验丰富 高效而出色地。11个在特定疾病和研究领域具有专业知识的咨询小组将促进 在网络内试行,并作为中心领导层和各个绩效站点的资源。 这项建议的四个具体目标是:1)在几个不同的 困扰整个南加州成人或儿童的紧急疾病类型;2)促进合作 在整个南加州的急诊医生和疾病专家之间进行试验设计和 在洛杉矶县和奥兰治县执行高质量的NSTN恢复和重建试验;3)促进 院前EMS系统与急诊接诊医院之间的协作,包括#年的专科接诊中心 创伤、中风和心脏复苏,在整个南加州进行试验设计和执行;以及4)确保 包括妇女在内的相当数量的紧急情况患者参加了SIREN临床试验, 儿童、西班牙裔美国人、非裔美国人和其他传统上代表不足的群体。

项目成果

期刊论文数量(0)
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JEFFREY L SAVER其他文献

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{{ truncateString('JEFFREY L SAVER', 18)}}的其他基金

Los Angeles - Southern California (LASC) NIH StrokeNet Regional Coordinating Center
洛杉矶 - 南加州 (LASC) NIH StrokeNet 区域协调中心
  • 批准号:
    9767886
  • 财政年份:
    2018
  • 资助金额:
    $ 25.71万
  • 项目类别:
Los Angeles - Southern California (LASC) NIH StrokeNet Regional Coordinating Center
洛杉矶 - 南加州 (LASC) NIH StrokeNet 区域协调中心
  • 批准号:
    10350100
  • 财政年份:
    2018
  • 资助金额:
    $ 25.71万
  • 项目类别:
Los Angeles - Southern California (LASC) NIH StrokeNet Regional Coordinating Center
洛杉矶 - 南加州 (LASC) NIH StrokeNet 区域协调中心
  • 批准号:
    10669559
  • 财政年份:
    2018
  • 资助金额:
    $ 25.71万
  • 项目类别:
Southern California Network Clinical Center (Hub) for SIREN Emergency Care Clinical Trails
SIREN 紧急护理临床试验南加州网络临床中心(中心)
  • 批准号:
    10626189
  • 财政年份:
    2017
  • 资助金额:
    $ 25.71万
  • 项目类别:
Southern California Network Clinical Center (Hub) for SIREN Emergency Care Clinical Trails
SIREN 紧急护理临床试验南加州网络临床中心(中心)
  • 批准号:
    10200906
  • 财政年份:
    2017
  • 资助金额:
    $ 25.71万
  • 项目类别:
Los Angeles - Southern California NINDS Stroke Trial Network (LASC NSTN)
洛杉矶 - 南加州 NINDS 中风试验网络 (LASC NSTN)
  • 批准号:
    8739691
  • 财政年份:
    2013
  • 资助金额:
    $ 25.71万
  • 项目类别:
Los Angeles - Southern California NINDS Stroke Trial Network (LASC NSTN)
洛杉矶 - 南加州 NINDS 中风试验网络 (LASC NSTN)
  • 批准号:
    8662444
  • 财政年份:
    2013
  • 资助金额:
    $ 25.71万
  • 项目类别:
Los Angeles Neurological Emergencies Treatment Trials (LA NETT)
洛杉矶神经紧急情况治疗试验 (LA NetT)
  • 批准号:
    8536972
  • 财政年份:
    2012
  • 资助金额:
    $ 25.71万
  • 项目类别:
Los Angeles Neurological Emergencies Treatment Trials (LA NETT)
洛杉矶神经紧急情况治疗试验 (LA NetT)
  • 批准号:
    8726501
  • 财政年份:
    2012
  • 资助金额:
    $ 25.71万
  • 项目类别:
Los Angeles Neurological Emergencies Treatment Trials (LA NETT)
洛杉矶神经紧急情况治疗试验 (LA NetT)
  • 批准号:
    8885929
  • 财政年份:
    2012
  • 资助金额:
    $ 25.71万
  • 项目类别:
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