Los Angeles - Southern California (LASC) NIH StrokeNet Regional Coordinating Center

在南加州，中风是第二大死亡原因，也是导致残疾的主要原因。它是 有效地开发预防中风、急性治疗和康复的新疗法势在必行。 此申请是续订NIH洛杉矶-南加州StrokeNet区域协调 中心(LASC StrokeNet RCC)，在美国拥有37个急性中风和康复医疗中心 洛杉矶县和奥兰治县，以及新墨西哥州，将在 预防、急性和恢复，高效和出色。参与该网络的医院包括7家 学术中心和30个学术-社区和社区混合医疗中心。十二个LASC StrokeNet 在特定神经血管研究领域具有专业知识的工作组促进在 并作为RCC领导层和个人绩效站点的资源。 这项建议的四个具体目标是：1)执行高质量的NIH StrokeNet急性和 在洛杉矶、奥兰治县和新墨西哥州进行的预防试验；2)执行高质量的NIH 洛杉矶、奥兰治县和新墨西哥州的StrokeNet恢复和康复试验；3) 确保大量未得到充分服务的人群参与NIH StrokeNet试验，包括妇女 拉美裔美国人、非裔美国人和其他少数族裔人口；以及4)受教育的人、居民、 医学生、医学预科学生和初级教职员工从事中风翻译研究。

Stroke is the 2nd leading cause of death and a leading cause of disability in Southern California. It is imperative that new treatments for stroke prevention, acute therapy, and recovery be efficiently developed. This application is to renew the NIH Los Angeles – Southern California StrokeNet Regional Coordinating Center (LASC StrokeNet RCC) that marshals a network of 37 acute stroke and rehabilitation medical centers in Los Angeles and Orange Counties, and New Mexico, which will perform 5-10 NIH StrokeNet trials in prevention, acute, and recovery, efficiently and excellently. Participating hospitals in the network include 7 academic and 30 mixed academic-community and community medical centers. Twelve LASC StrokeNet Working Groups with expertise in specific neurovascular research domains facilitate trial implementation within the Network and serve as a resource to the RCC leadership and to individual performance sites. The four specific aims of this proposal are to: 1) perform high quality NIH StrokeNet acute and prevention trials throughout Los Angeles and Orange Counties, and New Mexico; 2) perform high quality NIH StrokeNet recovery and rehabilitaiton trials throughout Los Angeles and Orange Counties, and New Mexico; 3) ensure participation of high volumes of underserved populations in NIH StrokeNet trials, including women, Hispanic-American, African-American, and other minority populations; and 4) educate fellows, residents, medical students, premedical students, and junior faculty to engage in stroke translational research.