Administrative Core

行政核心

• 批准号: 10438738
• 负责人: Nicholas F. LaRusso
• 金额: $ 31.94万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10438738
• 关键词: Administrative Supplement; Administrator; Advisory Committees; Award; Cell Communication; Cells; Clinic; Clinical; Clinical Sciences; Collaborations; Communication; Digestive System Disorders; Discipline; Educational Curriculum; Educational workshop; Ensure; Epigenetic Process; Equipment; Faculty; Feedback; Fostering; Funding; Gastroenterology; Genes; Genetic; Goals; Growth; Hepatology; Institution; Interdisciplinary Study; International; Journals; Leadership; Mentorship; Methodology; Microscopy; Midwestern United States; Modification; National Institute of Diabetes and Digestive and Kidney Diseases; Occupational activity of managing finances; Optics; Outcomes Research; Peer Review; Performance; Persons; Positioning Attribute; Process; Reagent; Research; Research Personnel; Resource Allocation; Resources; Science; Scientist; Services; Signal Transduction; Standardization; Structure; Technology; Time; Translational Research; United States National Institutes of Health; Update; Visit; base; career development; clinical center; cost effective; epigenomics; improved; instrument; interest; member; operation; programs; quality assurance; recruit; response; sabbatical; symposium

PROJECT SUMMARY: ADMINISTRATIVE CORE The objective of the C-SiG Administrative Core is to provide leadership for the overall direction of the Center and to optimize member benefits from Center Programs and Cores. C-SiG Administrative Core leadership is provided by Dr. N.F. LaRusso, Director, Dr. G.J. Gores, Co-Director, and Dr. V.H. Shah, Associate Director, in conjunction with an Executive Committee, an Internal Advisory Committee, and an External Advisory Committee. The Executive Committee is comprised of the Director, Co-Director, Associate Directors, Core Directors, the Leaders of the Mechanistic Research Theme groups (Intracellular Signaling, Cell-to-Cell Communication, and Genetics/Epigenetics), and key leaders within the Division of Gastroenterology and Hepatology, and meets monthly. The Internal Advisory Committee meets quarterly and provides regular input to the Executive Committee regarding the strategic direction of the Center and facilitates communication with institutional leaders The External Advisory Committee consists of five internationally prominent investigators who are leaders in digestive disease research and meets annually in person and by conference call as needed to provide regular feedback to the Executive Committee. An Administrator provides the necessary support for real-time financial management and operations of the Center. A newly recruited Core Project Manager performs day-to-day Core project management to improve standardization of core processes, streamline efficiency of workflows, and enhance deliverable quality. The Operations Committee consists of the Director, Co-director, Administrator and Core Project Manager and meets weekly to plan and manage C- SiG operations. The administrative leadership assures responsiveness of the C-SiG Cores to the needs of the members and provides oversight for Core functions. C-SiG's goals are to promote cell signaling science by: i) Fostering multidisciplinary research by expanding technical and collaborative capabilities of established GI scientists and attracting investigators from other disciplines; ii) Identifying and nurturing new GI investigators via a peer-reviewed Pilot and Feasibility (P/F) Program including career development workshops, curricula, and structured mentorship (19/26, 73% of P/F recipients achieving federal funding); iii) Offering core-based specialized equipment, technologies, methodologies, reagents, and expertise (Optical Microscopy, Clinical, and Gene Editing and Epigenomics Cores), with continuous core menu updates, quality assurance and assessments, and project management oversight in response to member feedback; iv) Supporting a robust Enrichment Program; and v) Promoting interactions between C-SiG with other NIDDK centers at Mayo (e.g., PKD Center) and existing DDRCCs, especially in the Midwest (i.e., Midwest DDRCC Alliance).

项目摘要：行政核心 C-SIG行政核心的目的是为中心的整体方向提供领导 并优化中心计划和核心的会员福利。 C-Sig行政核心领导是 由N.F.博士提供Larusso，G.J。博士戈尔斯（Gores），联合导演，以及 与执行委员会，内部咨询委员会和外部咨询 委员会。执行委员会由主任，联合主任，副董事，核心组成 导演，机械研究主题组的领导者（细胞内信号传导，细胞到细胞 交流，遗传学/表观遗传学），以及胃肠病学和分区内的主要领导者 肝病学，每月开会。内部咨询委员会每季度开会，并提供定期 有关中心战略方向的执行委员会的意见，并促进沟通 与机构领导人一起，外部咨询委员会由五个国际知名 研究人员是消化疾病研究的领导者，并每年与会议每年见面 根据需要致电给执行委员会的定期反馈。管理员提供 对实时财务管理和中心运营的必要支持。新招募的核心 项目经理执行日常核心项目管理以提高核心流程的标准化， 简化工作流程的效率，并提高可交付质量。运营委员会包括 董事，联合指导，管理员和核心项目经理，并每周开会以计划和管理C- SIG操作。行政领导确保C-Sig核心对需求的响应能力 成员并为核心功能提供监督。 C-SIG的目标是通过以下方式促进细胞信号科学。 i）通过扩大已建立GI的技术和协作能力来促进多学科研究 科学家并吸引来自其他学科的研究者； ii）识别和培养新的GI调查人员 通过经过同行评审的飞行员和可行性（P/F）计划，包括职业发展研讨会，课程， 和结构化指导（19/26，73％的P/F接收者获得联邦资金）； iii）提供基于核心的 专业设备，技术，方法，试剂和专业知识（光学显微镜，临床， 以及基因编辑和表观基因组学核心），具有连续的核心菜单更新，质量保证和 评估和项目管理监督，以应对会员反馈； iv）支持强大的 丰富计划； v）促进C-SIG与Mayo其他NIDDK中心之间的相互作用 （例如，PKD中心）和现有的DDRCC，特别是在中西部（即中西部DDRCC联盟）。