University Training Program in Biomolecular and Tissue Engineering

项目总结/摘要 目前的提案寻求继续支持长期存在的生物技术培训计划 由杜克大学的生物分子和组织工程中心（CBTE）管理。的 该生物技术培训计划的目标是在课堂上提供博士前培训， 实验室和科学界在设计，操作和定量表征， 生物分子，细胞和组织，特别强调这些技术的翻译及其 在生物技术产业中的发展。培训活动的重点是加强和多样化 我们的生物技术工作队伍，并准备下一代领导人谁将开拓新兴的新 生物药物开发、组织工程、基因和细胞治疗等领域。参与 博士预科生必须符合以下标准：（1）进行研究， （2）具有跨学科性质，是创新生物技术发展的核心;（3）至少 两名CBTE教师，一名来自生物医学科学，一名来自工程，在他们的博士论文 委员会;（3）出席每月工作进展学生研讨会系列;（4）完成工程 和生物医学科学课程，提供生物分子和组织工程的广度;（5）完成 四个学期的跨学科CBTE研讨会系列信贷，包括专门会议， （6）参加为期三个月的工业生物技术实习;（7）参加 年度CBTE杰出讲座和研讨会;（8）参加定期安排的生物技术- 重点职业发展研讨会和研讨会;以及（9）接受负责任行为培训 严谨性和可重复性。该跨学科培训计划包括37名教师， 校园，有22名来自普拉特工程学院的教师和15名来自非工程领域的教师， 包括5名在艺术与科学的Trinity学院，10名在基础医学科学和临床 杜克大学医学中心的部门。在过去的26年里，共有116名学生 接受生物分子和组织工程的博士前培训。我们的大多数学员 在生物技术行业担任领导职务，包括作为新公司的联合创始人 和生物技术新领域的先驱者，而其他人则在学术，医学或 政府的随着时间的推移，我们计划的一个特点是学员群体的多样性不断增加。 总的来说，这些活动无疑提高了我们受训人员的教育和准备价值 在生物技术行业和其他领域的职业生涯，正如我们广泛的业绩记录所证明的那样， 和定量结果测量。

PROJECT SUMMARY/ABSTRACT The current proposal seeks to continue support of the long-standing biotechnology training program administered by the Center for Biomolecular and Tissue Engineering (CBTE) at Duke University. The objective of this biotechnology training program is to provide predoctoral training in the classroom, laboratory, and scientific community in the design, manipulation, and quantitative characterization of biomolecules, cells and tissues with special emphasis on the translation of these technologies and their advancement within the biotechnology industry. Training activities are focused on enhancing and diversifying our biotechnology work force and preparing the next generation of leaders who will pioneer burgeoning new fields such as biologic drug development, tissue engineering, and gene and cell therapy. Participating predoctoral trainees are required to meet the following criteria: (1) perform research that is interdisciplinary in nature and is central to the development of innovative biotechnology; (2) have at least two CBTE faculty, one from biomedical sciences and one from engineering, on their doctoral dissertation committee; (3) present in the monthly work-in-progress student seminar series; (4) complete engineering and biomedical science courses that provide breadth in biomolecular and tissue engineering; (5) complete four semesters of the interdisciplinary CBTE seminar series for credit, including dedicated meetings with visiting speakers; (6) participate in a three-month industrial biotechnology internship; (7) present in the annual CBTE Distinguished Lecture and Symposium; (8) attend regularly scheduled biotechnology- focused career development seminars and workshops; and (9) undergo training in responsible conduct and rigor and reproducibility in research. This interdisciplinary training program includes 37 faculty across campus, with 22 faculty from the Pratt School of Engineering and 15 faculty from non-engineering fields, including 5 in the Trinity College of Arts & Sciences, and 10 in the Basic Medical Science and Clinical Departments of the Duke University Medical Center. Over the past 26 years, a total of 116 students have received predoctoral traineeships in biomolecular and tissue engineering. The majority of our trainees have obtained positions as leaders in the biotech industry, including as co-founders of new companies and pioneers in new areas of biotechnology, while others have pursued careers in academic, medicine, or government. A hallmark of our program has been the increased diversity of trainee cohort over time. Collectively, these activities decidedly increase the value of the education and preparation of our trainees for careers in the biotechnology industry and other fields, as demonstrated by our extensive track record and quantitative outcome measures.