Core B - Bioanalytical, Mass Spectroscopy, Imaging and Histology Core

核心B-生物分析、质谱学、成像和组织学核心 项目摘要/摘要 心肾和代谢性疾病研究中心(CMDRC)成立，以加强研究 基础设施和提供指导，以提高Cobre调查人员成功竞争的能力 美国国立卫生研究院的独立资助。生物分析、质谱学、成像和组织学核心B是 在第一阶段期间作为CMDRC的资源建立，这一核心对 科布雷初级调查员、飞行员格兰特调查员和来自当地历史悠久的黑人学院的调查员 和大学(HBCU)。在Cobre支持的第一阶段，Core B建立了以下关键服务 心肾和代谢性疾病研究人员以及众多研究人员 CMDRC成员。核心B提供对技术和服务的访问，否则这些技术和服务 在密西西比州有售。这包括整合的高度专业化的服务和最先进的资源 配备了专业人员，他们不仅能够进行各种基本研究 服务，但也能够提供培训和协助开发新的研究方法，以满足 科布雷调查人员不断变化的需求。核心B具有多种成分，包括生物分析/质量 提供集中式放射免疫分析(RIA)、ELISA法、HPLC法、LC/MS、 蛋白质组学、脂类组学和其他生化/化学分析，以及组织学/成像亚核心 提供最先进的成像设备以及组织学、免疫组织化学和其他 关键服务。来自UMMC超过15个不同的基础科学和临床系的教师除了 来自其他机构的研究人员，包括HBCU的杰克逊州立大学，使用了服务和资源 在Cobre支持的第一阶段期间由Core B提供。核心B提供的资源和服务包括 在第一阶段期间大幅扩展，这得到了新的最先进技术的支持 将设备连接到每个子核心。调查人员使用核心B促进了&gt；250出版物的产生 并为接受美国国立卫生研究院和其他非营利组织的许多外部资助提供了直接支持 资助机构。建立次核心作为充电中心启动了我们的业务计划 可持续发展和核心B将继续在我们成功的基础上再接再厉，以便我们能够为 现有基础设施、资源和服务，并扩展核心产品以满足心肾需求 以及UMMC的代谢性疾病研究人员。

CORE B – BIOANALYTICAL, MASS SPECTROSCOPY, IMAGING AND HISTOLOGY CORE PROJECT SUMMARY/ABSTRACT The Cardiorenal and Metabolic Diseases Research Center (CMDRC) was established to enhance research infrastructure and provide mentoring to increase the ability of COBRE investigators to successfully compete for independent NIH funding. The Bioanalytical, Mass Spectroscopy, Imaging and Histology Core B was established as a resource for the CMDRC during Phase I, and this core has had a transformative effect on COBRE junior investigators, Pilot Grant investigators, and investigators from local Historically Black Colleges and Universities (HBCUs). During Phase I of COBRE support, Core B established services critical to cardiorenal and metabolic diseases researchers in addition to numerous investigators who collaborate with members of the CMDRC. Core B provides access to technologies and services that would otherwise not be available in Mississippi. This includes consolidated, highly specialized services and state-of-the-art resources staffed by professional personnel who are not only capable of performing a variety of essential research services, but are also able to provide training and assist in the development of new research methods to meet the changing needs of COBRE investigators. Core B has multiple components including the Bioanalytical/Mass Spec Sub-Cores that provide centralized radioimmunoassay (RIA), ELISA, HPLC, LC/Mass spectroscopy, proteomics, lipidomics and other biochemical/chemistry analyses, and the Histology/Imaging Sub-Cores that provide access to state-of–the-art imaging equipment as well as histology, immunohistochemistry, and other key services. Faculty from over 15 different basic science and clinical departments at UMMC in addition to researchers from other institutions including Jackson State University, a HBCU, used services and resources provided by Core B during Phase I of COBRE support. Resources and services provided by Core B were substantially expanded during Phase I and this was supported by the addition of new state-of-the-art equipment to each Sub-Core. Usage of Core B by investigators facilitated the generation of >250 publications and provided direct support for the receipt of many extramural funded grants from NIH and other non-profit funding agencies. Establishment of Sub-Cores as Recharge Centers initiated our business plan for sustainability and Core B will continue to build upon our success so that we can provide continuous support for existing infrastructure, resources and services, and expand Core offerings to meet the needs of cardiorenal and metabolic disease researchers at UMMC.