University of Utah Genetics Training Program
University of Utah Genetics Training Program
批准号:
10654719
负责人:
KENT G GOLIC
金额:
$58.88万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-07-01 至 2026-06-30
中文摘要
项目概要/摘要
犹他州大学(UofU)拟议的遗传学培训计划(UGTP)将提供深入培训
在遗传学为12个博士生的多元化群体,武装他们与科学和专业
进行独立和严格的研究,并成为领导者所需的知识和技能。
生物医学研究人员。U of U有一个完善的,成功的研究生培训工作,
遗传学研究,包括长期运行的遗传学T32(45年)。拟议的新大学生就业培训计划是一项密集的
为期两年的定量分析培训计划,严格和透明的实验实践,
专业技能、科学道德实践、导师制和公平/包容性。这些基本
目标支持未来多方面的领导者和导师在遗传学研究的发展。
UGTP在他们的职业生涯的形成阶段,在他们的第二和第三年的研究生院从事学员。
该计划的好处扩展之前和之后的两年密集培训期。完成
先决条件的第一年研究生课程,包括基本的传播遗传学,研究中的道德实践,
批判性思维,假设发展,以及对严谨性和可重复性的理解是必要的,
UGTP。成功通过第一年年底举行的Capstone考试的学生,评估实习生
独立研究的潜力和科学分析和实验思维的严谨性,有资格获得
UGTP。每年大约50名TGE学生中约有12%被选中成为学员。
学员们全年参加一系列丰富的活动。培训计划的主要特点是
由PD领导的研讨会课程,仅限于学员,其中学生i)介绍研究,批判性地评估
进展,并讨论科学的最佳做法;在ii)RCR和iii)严谨性方面开展持续培训,
透明度和可重复性;参加关于四)专业发展,五)指导的讲习班;以及
vi)识别和应对有偏见的行为。学员每年提交他们的研究进展,
整个UofU遗传学社区,并选择和主机访问遗传学讲者全年。三
定量和遗传学分析的高级课程提供了遗传学领域的广泛培训。
UGTP提供研究和专业发展方面的持续指导:学员培养国内流离失所者
与项目主任一起,从UGTP指导委员会中额外聘请一名导师,提供指导
与UGTP沟通,并参加旨在职业发展和建立
包容性社区。经过两年的UGTP支持的研究与61 UGTP教师之一,学员
通过一项新的近同伴指导计划保持参与,这是一项支持
科学和文化的发展和指导我们的学员的技能。UGTP使整个UofU
遗传学社区全年通过外部扬声器,遗传学研讨会的概念,和一个年度
务虚会包括学员讲座,全体演讲者,以及来自UofU遗传学社区的海报展示。
英文摘要
PROJECT SUMMARY/ABSTRACT
The proposed Genetics Training Program (UGTP) at the University of Utah (UofU) will provide in-depth training
in Genetics for a diverse group of 12 predoctoral students, arming them with scientific and professional
knowledge and skills needed to conduct independent and rigorous research and become leaders within the
biomedical research workforce. The U of U has a well-established, successful graduate training effort in
genetics research, including a long-running Genetics T32 (45 years). The proposed new UGTP is an intensive
two-year program of training in quantitative analysis, rigorous and transparent experimental practices,
professional skills, the ethical practice of science, mentorship, and equity/inclusivity. These foundational
objectives support the development of future multi-dimensional leaders and mentors in genetics research.
The UGTP engages trainees at a formative stage of their career, in their 2nd and 3rd years of graduate school.
Benefits of the program extend both before and after the intensive two-year training period. Completion of a
pre-requisite first year graduate curriculum covering basic transmission genetics, ethical practices in research,
critical thinking, hypothesis development, and understanding of rigor and reproducibility is required for the
UGTP. Students who successfully pass a Capstone Exam administered at the end of Year 1, assessing trainee
potential for independent research and rigor in scientific analysis and experimental thinking, are eligible for the
UGTP. Each year about 12% of the approximately 50 TGE students are selected to become trainees.
Trainees convene year-round in a suite of enriching activities. The central feature of the Training Program is a
seminar course led by the PDs, limited to trainees, in which the students i) present research, critically evaluate
progress, and discuss scientific best practices; undertake continued training in ii) RCR and iii) rigor,
transparency, and reproducibility; participate in workshops on iv) professional development, v) mentoring; and
vi) recognizing and responding to biased behaviors. Trainees present their research progress annually before
the entire UofU Genetics community and select and host visiting genetics speakers throughout the year. Three
advanced courses in quantitative and genetics analyses provide a breadth of training in the field of Genetics.
The UGTP provides continuous mentorship in research and professional development: trainees develop IDPs
with the Program Directors, adopt an extra mentor from the UGTP Steering Committee who provides guidance
and communication with the UGTP, and participate in events aimed at career development and building an
inclusive community. Following two years of UGTP-supported research with one of 61 UGTP faculty, trainees
remain engaged through a novel initiative of near-peer mentorship, a program feature that supports the
scientific and cultural development and mentoring skills of our trainees. The UGTP engages the entire UofU
genetics community year-round through external speakers, Concepts in Genetics Seminars, and an Annual
Retreat featuring trainee talks, plenary speakers, and poster presentations from the UofU genetics community.
期刊论文(12)
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DOI:
10.3390/cells11223550
发表时间:
2022-11-10
期刊:
CELLS
影响因子:
6
作者:
[Hill, Hunter J., Golic, Kent G.]
通讯作者:
Golic, Kent G.
Histone 4 lysine 5/12 acetylation enables developmental plasticity of Pristionchus mouth form.
组蛋白 4 赖氨酸 5/12 乙酰化使 Pristionchus 口腔形态具有发育可塑性。
DOI:
10.1038/s41467-023-37734-z
发表时间:
2023-04-13
期刊:
NATURE COMMUNICATIONS
影响因子:
16.6
作者:
[Werner, Michael S. S., Loschko, Tobias, King, Thomas, Reich, Shelley, Theska, Tobias, Franz-Wachtel, Mirita, Macek, Boris, Sommer, Ralf J. J.]
通讯作者:
Sommer, Ralf J. J.
DOI:
10.1371/journal.pgen.1010880
发表时间:
2023-10
期刊:
PLoS genetics
影响因子:
4.5
作者:
[]
通讯作者:
DOI:
10.1093/gbe/evad119
发表时间:
2023-07-03
期刊:
GENOME BIOLOGY AND EVOLUTION
影响因子:
3.3
作者:
[Hilbert, Zoe A., Haffener, Paige E., Young, Hannah J., Schwiesow, Mara J. W., Leffler, Ellen M., Elde, Nels C.]
通讯作者:
Elde, Nels C.
FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma.
FoxA1/2 依赖性表观基因组重编程驱动肺腺癌谱系转换。
DOI:
10.1101/2023.10.30.564775
发表时间:
2023
期刊:
bioRxiv : the preprint server for biology
影响因子:
--
作者:
[Gillis,Katherine, Orellana,WalterA, Wilson,Emily, Parnell,TimothyJ, Fort,Gabriela, Dadzie,HeadtloveEssel, Zhang,Xiaoyang, Snyder,EricL]
通讯作者:
Snyder,EricL
University of Utah Genetics Training Program
-
批准号:10207203
-
项目类别:
-
资助金额:$53.73万
-
财政年份:2021
-
负责人:KENT G GOLIC
-
依托单位:
University of Utah Genetics Training Program
-
批准号:10431938
-
项目类别:
-
资助金额:$57.66万
-
财政年份:2021
-
负责人:KENT G GOLIC
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依托单位:
Chromosome breakage, pairing and replication: impacts on cell fate and function
-
批准号:10388397
-
项目类别:
-
资助金额:$38.13万
-
财政年份:2020
-
负责人:KENT G GOLIC
-
依托单位:
Chromosome breakage, pairing and replication: impacts on cell fate and function
-
批准号:10612872
-
项目类别:
-
资助金额:$38.13万
-
财政年份:2020
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负责人:KENT G GOLIC
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依托单位:
Mechanism of Imprinting in Drosophila
-
批准号:6776619
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项目类别:
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资助金额:$20.93万
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财政年份:2004
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负责人:KENT G GOLIC
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依托单位:
Mechanism of Imprinting in Drosophila
-
批准号:6917979
-
项目类别:
-
资助金额:$20.93万
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财政年份:2004
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负责人:KENT G GOLIC
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依托单位:
Mechanism of Imprinting in Drosophila
-
批准号:7100281
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项目类别:
-
资助金额:$20.44万
-
财政年份:2004
-
负责人:KENT G GOLIC
-
依托单位:
Mechanism of Imprinting in Drosophila
-
批准号:7260495
-
项目类别:
-
资助金额:$19.85万
-
财政年份:2004
-
负责人:KENT G GOLIC
-
依托单位:
Drosophila Telomere Function
-
批准号:7250901
-
项目类别:
-
资助金额:$30.12万
-
财政年份:2001
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负责人:KENT G GOLIC
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依托单位:
Responses to Telomere Loss
-
批准号:8239016
-
项目类别:
-
资助金额:$30.92万
-
财政年份:2001
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负责人:KENT G GOLIC
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依托单位:
Gene Targeting in Drosophila
-
批准号:6788857
-
项目类别:
-
资助金额:$28.41万
-
财政年份:2001
-
负责人:KENT G GOLIC
-
依托单位:
Responses to Telomere Loss
-
批准号:8451363
-
项目类别:
-
资助金额:$29.89万
-
财政年份:2001
-
负责人:KENT G GOLIC
-
依托单位:
Drosophila Telomere Function
-
批准号:7146621
-
项目类别:
-
资助金额:$31.02万
-
财政年份:2001
-
负责人:KENT G GOLIC
-
依托单位:
Gene Targeting in Drosophila
-
批准号:6603556
-
项目类别:
-
资助金额:$6.36万
-
财政年份:2001
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负责人:KENT G GOLIC
-
依托单位:
Gene Targeting in Drosophila
-
批准号:6484846
-
项目类别:
-
资助金额:$23.85万
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财政年份:2001
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负责人:KENT G GOLIC
-
依托单位:
Gene Targeting in Drosophila
-
批准号:6651619
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项目类别:
-
资助金额:$28.41万
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财政年份:2001
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负责人:KENT G GOLIC
-
依托单位:
Drosophila Telomere Function
-
批准号:7459864
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项目类别:
-
资助金额:$30.12万
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财政年份:2001
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负责人:KENT G GOLIC
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依托单位:
Drosophila Telomere Function
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批准号:7643901
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项目类别:
-
资助金额:$30.12万
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财政年份:2001
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负责人:KENT G GOLIC
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依托单位:
Responses to Telomere Loss
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批准号:9106534
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项目类别:
-
资助金额:$31.85万
-
财政年份:2001
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负责人:KENT G GOLIC
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依托单位:
Gene Targeting in Drosophila
-
批准号:6526439
-
项目类别:
-
资助金额:$28.48万
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财政年份:2001
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负责人:KENT G GOLIC
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依托单位:
海外基金