Nedd4-2: a new player in polycystic kidney disease
Nedd4-2: a new player in polycystic kidney disease
批准号:
nhmrc : 1099307
负责人:
A/Pr Ian Smyth
金额:
$46.07万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31
中文摘要
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英文摘要
Polycystic kidney disease (PKD) is a life threatening disorder affecting over 12 million people worldwide. This project is based on our discovery of a new gene that controls PKD. Using kidney specific gene knockout, biochemical and cellular approaches we will now address how this gene controls PKD. The results from this study will lead to better understanding of the underlying mechanisms that cause PKD, thus providing possible new targets for therapeutic interventions.
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