ABCA12 – a New Regulator of Cellular Lipid Metabolism and Inflammation
ABCA12 – a New Regulator of Cellular Lipid Metabolism and Inflammation
批准号:
nhmrc : 1020281
负责人:
A/Pr Ian Smyth
金额:
$52.46万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31
中文摘要
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英文摘要
Dysregulation of cholesterol metabolism plays a key role in a number of diseases – from diabetes and atherosclerosis to neurological and skin disorders. Mechanisms of regulation of cholesterol metabolism are poorly understood. We have recently discovered a new pathway regulating cholesterol metabolism and in this study we will investigate molecular, cellular and physiological mechanisms of this pathway and will identify the possibilities to target it for therapeutic intervention.
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海外基金