Support for Vector Biology Training for Sustainable Control of Vector Borne diseases in East Africa

支持媒介生物学培训以可持续控制东非媒介传播疾病

• 批准号: 10675897
• 负责人: Serap AKSOY
• 金额: $ 25.04万
• 依托单位: BIOTECHNOLOGY RESEARCH INSTITUTE-KALRO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2027-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10675897
• 关键词: Address; Administrator; Adoption; Africa; Africa South of the Sahara; African; Agriculture; Animals; Award; Bioethics; Biology; Biotechnology; Clinical; Consultations; Country; Disease; Ecology; Education; Educational workshop; Environmental Health; Epidemiology; Faculty; Genomics; Human; Institution; Kenya; Knowledge; Laboratories; Leadership; Livestock; Manuscripts; Medical Research; Mentorship; Output; Participant; Persons; Physiology; Policy Maker; Population Genetics; Postdoctoral Fellow; Practice Management; Preparation; Public Health; Public Health Schools; Research; Research Institute; Research Personnel; Science; Scientist; Tanzania; Teacher Professional Development; Technology; Training; Uganda; Universities; Vector-transmitted infectious disease; burden of illness; career; data management; editorial; empowerment; evidence base; innovation; institutional capacity; low and middle-income countries; mathematical model; neglected tropical diseases; next generation; peer; programs; research and development; skills; training opportunity; vector; vector control; vector management strategies; vector-borne; virtual; webinar

Vector-borne and neglected tropical diseases (VBDs and NTDs, respectively) are endemic and emerging threats in sub-Saharan Africa (sSA). In this renewal application, scientists from Kenya Agricultural and Livestock Research Organization, Biotechnology Research Institute (BioRI-KALRO), and Yale School of Public Health (YSPH) will partner with Kenya Medical Research Institute (KEMRI), Gulu University (GU) and Vector and Vector-Borne Diseases Institute (VVBDI) and their peers in Kenya, Uganda and Tanzania with support of the East African Science and Technology Commission (EASTECO) to strengthen Vector Biology (VB) education and research capacity in order to advance vector control applications and reduce disease burden in East Africa. Our specific objectives are to: Aim 1) Empower early-career researchers in East Africa. Our training will target early-career scientists, including post-doctoral scholars and junior level faculty. We will transfer knowledge necessary to advance the state-of-the-art laboratory and field research skills, mathematical modeling and data management within broad fields of vector physiology, ecology, population genetics/genomics and epidemiology. We will establish regional network(s) of early-career researchers in LMIC institutions to support the next-generation of researchers and field practitioners and policy makers. Our program will prepare trainees with necessary skills to establish independent research programs, and to advise on sustainable and evidence-based strategies for in-country VC and disease elimination programs, and promote public discussions and consultations to advance downstream delivery capacity of innovative and integrated human, animal and environmental health VC technologies. Aim 2) Develop leadership and institutional capacity to disseminate knowledge on innovative VC applications. We will offer in-person and/or virtual training and mentorship opportunities in bioethics, proficient clinical and laboratory practices, vector management and biosafety to early-career scientists from LMIC institutions. We will also train faculties in manuscript preparation, grantsmanship, and editorial capabilities and administrators in best-practices for the management of research and development (R&D) activities. Working with our network institutions and public health agencies in the LMICs, we will identify and address barriers to downstream application and adoption of research outputs relavant for VBZD control. During the course of this award, we will support advanced training of 8-10 early career scientists for a two-year period in LMIC institutions, and present up to five workshops/webinars annually to broad program participants in different LMIC institutions. We will provide a leadership training opportunity to two advanced researchers at YSPH for 3-months annually to advance research content and mentorship/administration skills.

病媒传播和被忽视的热带病（分别为VBD和NTD）是地方性疾病， 撒哈拉以南非洲（sSA）的新威胁。在这份更新申请中，肯尼亚农业科学家 和牲畜研究组织，生物技术研究所（BioRI-KALRO），耶鲁大学 公共卫生（YSPH）将与肯尼亚医学研究所（KEMRI），古卢大学（GU）和 病媒和病媒传播疾病研究所（VVBDI）及其在肯尼亚、乌干达和坦桑尼亚的同行， 支持东非科学和技术委员会加强病媒生物学 (VB)提高教育和研究能力，以推进病媒控制应用和减少疾病 东非的负担。我们的具体目标是： 目标1：增强东非早期职业研究人员的能力。 我们的培训将针对早期职业科学家，包括博士后学者和初级教师。 我们将转让必要的知识，以推进国家的最先进的实验室和实地研究技能， 数学建模与数据管理 内 广泛的病媒生理学、生态学、人口学领域 遗传学/基因组学和流行病学。我们将在以下地区建立早期职业研究人员的区域网络： LMIC机构支持下一代研究人员、实地从业人员和政策制定者。我们 该计划将为学员提供必要的技能，以建立独立的研究计划，并建议 国内风险投资和疾病消除计划的可持续和循证战略，以及 促进公众讨论和协商，以提高创新和 整合人类、动物和环境健康风险投资技术。 目标2）发展领导能力和机构能力，以传播关于创新性风险投资应用的知识。 我们将提供生物伦理学方面的面对面和/或虚拟培训和指导机会， 临床和实验室实践，病媒管理和生物安全，以早期职业科学家从LMIC 机构职能体系我们还将培训教师的稿件准备，语法和编辑能力 研究和开发（R&D）活动管理的最佳实践。 我们将与我们在中低收入国家的网络机构和公共卫生机构合作， 下游应用和采用VBZD控制相关研究成果的障碍。 在这个奖项的过程中，我们将支持8-10个早期职业科学家的高级培训， 为期两年的LMIC机构，并提出了多达五个研讨会/网络研讨会，每年广泛的计划 不同LMIC机构的参与者。我们将提供一个领导培训机会，以两个先进的 研究人员在YSPH每年3个月，以提高研究内容和指导/管理技能。