Alterations and Renovations

俄克拉荷马州共享临床和转化资源（OSCTR）的临床资源核心提供 专业的临床设施，对参与者活动的支持，监管协助，以及各种患者 注册表、存储库和相关临床数据，这对临床和 OSCTR研究人员以及我们的合作伙伴和附属合作机构的翻译研究。目前我们的 加热和冷却水泵遍布我们的临床研究单位，样品处理和 俄克拉荷马州的生物储存实验室、临床研究实验室和相关会议室 医学研究基金会（OMRF）已接近其生命的尽头，冗余有限， 达到行业标准。在这份改建和装修申请中，我们要求30万美元更换我们的 水泵配备节能设备，在停电时提供备用能力， 失败此外，我们还将增加数字控制驱动系统，以提高能源效率和远程控制。 在紧急情况下进行监控。这些改建和翻新对临床至关重要 资源核心，因为这些泵是将冷冻水从健康中心带到OMRF园区所必需的。 科学中心，这是我们有限的访问，锁定步入式冷藏室的操作所需的， 保持冷冻治疗用于临床研究和试验，以及冷冻储存 OSCTR生物储存库的各种收藏。这种冷冻水也需要用于步入式冷藏室 和冷冻机在实验室的临床和转化研究调查员在同一查普曼， Milligan中心和Acree-Woodworth大楼作为临床研究单位和生物储存库。此外，委员会认为， 这六个更新的系统将增加临床研究和输液领域的空气交换， 我们的临床研究和试验参与者的空气传播感染风险。这增加了空气交换能力 也将有助于在会议中允许更大的临床和转化研究会议 中心，并增加CTR实验室的空气交换，每个实验室都有多名员工。OMRF 认识到这种更新的设备对于OSCTR服务、其他临床和转化研究至关重要 科学家和多研究者项目，并承诺提供超过30万美元的额外费用， 国家卫生研究院的政策和程序允许完成这个项目。

The Clinical Resources Core of the Oklahoma Shared Clinical and Translational Resources (OSCTR) provides specialized clinical facilities, support for participant activities, regulatory assistance, and a variety of patient registries, repositories, and associated clinical data, making it essential to the growth of clinical and translational research of OSCTR investigators and our partner and affiliated partner institutions. Currently, our heating and cooling water pumps located throughout our clinical research unit, sample processing and biorepository laboratories, clinical research laboratories, and associated conference rooms at the Oklahoma Medical Research Foundation (OMRF) are nearing the end of their life, have limited redundancy, and are not up to industry standards. In this Alterations and Renovations Request, we request $300,000 to replace our water pumps with energy-efficient equipment that provides backup capabilities in case of power outages or failure. In addition, we will add digital control drive systems, allowing for improved energy efficiency and remote monitoring and control in an emergency. These alterations and renovations are critical to the Clinical Resources Core, as these pumps are necessary to bring chilled water to the OMRF campus from the Health Sciences Center which is required for the operation of our limited access, locked walk-in cold room for maintaining refrigerated therapeutics for clinical research and trials, as well as with freezer storage of the various collections of the OSCTR Biorepository. This chilled water is also required for the walk-in cold rooms and freezers in the laboratories of clinical and translational research investigators in the same Chapman, Milligan Center and Acree-Woodworth buildings as the Clinical Research Unit and Biorepository. Furthermore, these six updated systems will increase air exchanges in the clinical research and infusion areas, reducing the risk of airborne infection for our clinical research and trial participants. This increased air exchange capacity will also be helpful in allowing larger group clinical and translational research meetings in the conference center and in increasing air exchanges in CTR laboratories which each contain multiple employees. OMRF recognizes that this updated equipment is crucial for OSCTR services, other clinical and translational research scientists, and multi-investigator projects and is committed to providing additional costs over $300,000 or not allowed by NIH Policies and Procedures to complete this project.