Alterations and Renovations

俄克拉荷马州临床资源核心共享临床和翻译资源(OSCTR)提供 专门的临床设施，对参与者活动的支持，监管协助，以及各种患者 注册表、存储库和相关的临床数据，这对临床和 OSCTR调查人员以及我们的合作伙伴和附属合作机构的翻译研究。目前，我们的 供暖和冷却水泵遍布我们的临床研究单位，样品处理和 位于俄克拉何马州的生物库实验室、临床研究实验室和相关会议室 医学研究基金会(OMRF)正在接近生命的尽头，拥有有限的冗余，而不是 符合行业标准。在这项改建和翻新申请中，我们要求300,000美元来更换我们的 配备节能设备的水泵，可在停电或停电时提供备用功能 失败了。此外，我们还将增加数字控制驱动系统，以提高能效和远程 紧急情况下的监控和控制。这些改变和翻新对临床至关重要 资源核心，因为这些泵是将冷水从卫生局输送到OMRF园区所必需的 科学中心，这是我们有限的通道、上锁的步入式冷藏室运行所必需的 维持临床研究和试验的冷藏疗法，以及冷冻储存 OSCTR生物库的各种收藏品。无障碍冷藏室也需要这种冷水。 在同一个查普曼的临床和转化性研究调查人员的实验室里， 米利根中心和艾瑞-伍德沃斯大楼作为临床研究单位和生物库。此外， 这六个更新的系统将增加临床研究和输液领域的空气交换，减少 我们的临床研究和试验参与者面临空气传播感染的风险。这增加了空气交换能力 还将有助于在会议中召开更大规模的临床和转化性研究会议 中心和增加CTR实验室的空气交换，每个实验室都有多名员工。OMRF 认识到这种更新的设备对OSCTR服务、其他临床和转译研究至关重要 科学家和多研究员项目，并承诺提供超过300,000美元的额外成本 在美国国立卫生研究院的政策和程序允许下完成这一项目。

The Clinical Resources Core of the Oklahoma Shared Clinical and Translational Resources (OSCTR) provides specialized clinical facilities, support for participant activities, regulatory assistance, and a variety of patient registries, repositories, and associated clinical data, making it essential to the growth of clinical and translational research of OSCTR investigators and our partner and affiliated partner institutions. Currently, our heating and cooling water pumps located throughout our clinical research unit, sample processing and biorepository laboratories, clinical research laboratories, and associated conference rooms at the Oklahoma Medical Research Foundation (OMRF) are nearing the end of their life, have limited redundancy, and are not up to industry standards. In this Alterations and Renovations Request, we request $300,000 to replace our water pumps with energy-efficient equipment that provides backup capabilities in case of power outages or failure. In addition, we will add digital control drive systems, allowing for improved energy efficiency and remote monitoring and control in an emergency. These alterations and renovations are critical to the Clinical Resources Core, as these pumps are necessary to bring chilled water to the OMRF campus from the Health Sciences Center which is required for the operation of our limited access, locked walk-in cold room for maintaining refrigerated therapeutics for clinical research and trials, as well as with freezer storage of the various collections of the OSCTR Biorepository. This chilled water is also required for the walk-in cold rooms and freezers in the laboratories of clinical and translational research investigators in the same Chapman, Milligan Center and Acree-Woodworth buildings as the Clinical Research Unit and Biorepository. Furthermore, these six updated systems will increase air exchanges in the clinical research and infusion areas, reducing the risk of airborne infection for our clinical research and trial participants. This increased air exchange capacity will also be helpful in allowing larger group clinical and translational research meetings in the conference center and in increasing air exchanges in CTR laboratories which each contain multiple employees. OMRF recognizes that this updated equipment is crucial for OSCTR services, other clinical and translational research scientists, and multi-investigator projects and is committed to providing additional costs over $300,000 or not allowed by NIH Policies and Procedures to complete this project.