Integrated Services Core

综合服务核心

基本信息

项目摘要

INTEGRATED SERVICES CORE ABSTRACT: The Regional Biocontainment Laboratory (RBL) within the Center for Vaccine Research (CVR) at the University of Pittsburgh is the biosafety level-3 (BSL-3) hub for infection biology. The mission of the RBL is threefold, to work on pathogen emergence, evolution and host-to-host transmission, to study the pathogenesis of emerging infectious diseases and to accelerate pre-clinical development of novel interventions and medical countermeasures for pandemic preparedness and biodefense. Our vision is to be a globally recognized, highly- collaborative, creative and forward-facing team of infection biologists who are poised to respond to emerging biological threats both at the national and international level. The entire facility is registered with the Division of Select Agents and Toxins (DSAT). It brings together infection biologists and clinicians from a variety of disciplines who require BSL-3 and animal (A)BSL-3 facilities for their wide ranging viral and bacterial research programs. Biocontainment work is operationally complex, infrastructure-dense, and comprehensively regulated. Running BSL-3 laboratories safely, securely and successfully demands having a well-organized and highly integrated team of administrators, scientists, biosafety/biosecurity professionals, engineers/facilities staff and veterinarians/zootechnical staff. This is especially important in multi-pathogen, multi-user research facilities that study standard and select agent BSL-3 pathogens. The Integrated Services Core will deliver a wide range of high quality BSL-3 and ABSL-3 services for internal users and external collaborators. These will be rigorously overseen by Academic and Service Leads and reviewed annually with the assistance of an external RBL Director, other BSL-3 experts and an internal Scientific Advisory Group. Operational support for the RBL in Pittsburgh will ensure we are ready to support any national response to a range of emerging infectious diseases in the event of another pandemic or bioterrorism attack. Supporting this cohort of BSL-3 scientists, who can pivot to work on new pathogens in an emergency, is certain to pay dividends.
综合服务核心

项目成果

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William Paul Duprex其他文献

William Paul Duprex的其他文献

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{{ truncateString('William Paul Duprex', 18)}}的其他基金

Operations Core
运营核心
  • 批准号:
    10793943
  • 财政年份:
    2023
  • 资助金额:
    $ 115.86万
  • 项目类别:
Pitt RBL
皮特·RBL
  • 批准号:
    10793942
  • 财政年份:
    2023
  • 资助金额:
    $ 115.86万
  • 项目类别:
Practices Core
实践核心
  • 批准号:
    10793944
  • 财政年份:
    2023
  • 资助金额:
    $ 115.86万
  • 项目类别:
Administrative Supplement for Upgrading the University of Pittsburgh Regional Biocontainment Laboratory within The Center for Vaccine Research
升级匹兹堡大学疫苗研究中心区域生物防护实验室的行政补充
  • 批准号:
    10631339
  • 财政年份:
    2022
  • 资助金额:
    $ 115.86万
  • 项目类别:
Development of multivalent, ultrapotent nanobody cocktails for SARS-CoV-2 neutralization
开发用于中和 SARS-CoV-2 的多价、超强纳米抗体混合物
  • 批准号:
    10444442
  • 财政年份:
    2022
  • 资助金额:
    $ 115.86万
  • 项目类别:
Upgrading the University of Pittsburgh Regional Biocontainment Laboratory within The Center for Vaccine Research
升级疫苗研究中心内的匹兹堡大学区域生物防护实验室
  • 批准号:
    10394474
  • 财政年份:
    2021
  • 资助金额:
    $ 115.86万
  • 项目类别:
Shifting a Paradigm in Vaccine Safety: From Empirical to Rational Attenuation
转变疫苗安全范式:从经验衰减到理性衰减
  • 批准号:
    8664340
  • 财政年份:
    2013
  • 资助金额:
    $ 115.86万
  • 项目类别:
Shifting a Paradigm in Vaccine Safety: From Empirical to Rational Attenuation
转变疫苗安全范式:从经验衰减到理性衰减
  • 批准号:
    8504483
  • 财政年份:
    2013
  • 资助金额:
    $ 115.86万
  • 项目类别:
Shifting a Paradigm in Vaccine Safety: From Empirical to Rational Attenuation
转变疫苗安全范式:从经验衰减到理性衰减
  • 批准号:
    9064740
  • 财政年份:
    2013
  • 资助金额:
    $ 115.86万
  • 项目类别:
Shifting a Paradigm in Vaccine Safety: From Empirical to Rational Attenuation
转变疫苗安全范式:从经验衰减到理性衰减
  • 批准号:
    8852530
  • 财政年份:
    2013
  • 资助金额:
    $ 115.86万
  • 项目类别:

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合作研究:目击者识别程序中的社会影响:盲目的管理员行为是否会放大嫌疑人偏见的影响?
  • 批准号:
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