Effects of pandemic-related disruption to social connectedness on the brain and emotional wellbeing in adolescents

与流行病相关的社会联系中断对青少年大脑和情绪健康的影响

基本信息

  • 批准号:
    10374459
  • 负责人:
  • 金额:
    $ 84.8万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-03-01 至 2022-04-30
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY The social reorientation of the adolescent period is accompanied by extensive neurodevelopmental changes. To understand the neurodevelopmental networks underlying responses to social environments and how social connectedness influences neurodevelopment, manipulation of social connectedness among youth is required, which is impossible in a large-scale setting. In 2020, the COVID pandemic happened, in the midst of longitudinal follow-up of participants in the Adolescent Brain Cognition Development (ABCD) study, inducing dramatic changes to social connectedness in adolescents in the study. Because the levels of stay-at-home restriction were imposed agnostically to participants' pre-pandemic status, this becomes a naturally occurred experiment on social connectedness among adolescents. Together with the comprehensive pre-pandemic assessments, longitudinal follow-up with surveys and geolocation data collected during the pandemic period, and the resumption of multimodal imaging scans and regular assessments restarting during, and continuing after 2021, we can use longitudinal ABCD data to critically examine the relationships between social connectedness and neurodevelopment among youth. In particular, we propose to use ABCD data to investigate 1) the neurobiological and social factors (pre-pandemic) that render an individual more sensitive to the disruption of social connectedness (peri-pandemic), contributing to emotional turmoil during and beyond the pandemic period; 2) the modulating factors that buffer/exacerbate the emotion responses during a prolonged period of social disruption (peri-pandemic); and 3) the extent of deviation in neurodevelopment after the pandemic (post-pandemic) in relation to the varying levels of social disruptions in ABCD participants during the pandemic. We will pursue these aims by utilizing a novel combination of methods from high-dimensional data analysis and population inference, innovatively tailoring the analytic strategies to avoid potential biases and spurious associations. The proposed research is of high public health interest because the identified neurobiological mechanisms underlying the emotional responses toward the disruption of social connectedness will provide novel insights for therapeutics and public health interventions in adolescents, due to the population-informed ABCD sample. By sharing our developed tools and derived social variables for this research program, we will impact the field immediately. These novel analytic tools enable us and others to more deeply investigate with ABCD data, neurodevelopmental processes specifically related to social connectedness. Results can inform peri- and post-pandemic clinical practice to regain and improve mental health in youth.
项目总结

项目成果

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Fiona C Baker其他文献

Fiona C Baker的其他文献

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{{ truncateString('Fiona C Baker', 18)}}的其他基金

Effects of pandemic-related disruption to social connectedness on the brain and emotional wellbeing in adolescents
与流行病相关的社会联系中断对青少年大脑和情绪健康的影响
  • 批准号:
    10681759
  • 财政年份:
    2022
  • 资助金额:
    $ 84.8万
  • 项目类别:
Emotion Regulation and Sleep in Alcohol Use Disorder
酒精使用障碍中的情绪调节和睡眠
  • 批准号:
    10254381
  • 财政年份:
    2020
  • 资助金额:
    $ 84.8万
  • 项目类别:
Emotion Regulation and Sleep in Alcohol Use Disorder
酒精使用障碍中的情绪调节和睡眠
  • 批准号:
    10041719
  • 财政年份:
    2020
  • 资助金额:
    $ 84.8万
  • 项目类别:
ABCD-USA Consortium: Research Project
ABCD-美国联盟:研究项目
  • 批准号:
    9150540
  • 财政年份:
    2015
  • 资助金额:
    $ 84.8万
  • 项目类别:
10/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT SRI
10/21 ABCD-美国联盟:SRI 研究项目现场
  • 批准号:
    10596278
  • 财政年份:
    2015
  • 资助金额:
    $ 84.8万
  • 项目类别:
ABCD-USA Consortium: Research Project
ABCD-美国联盟:研究项目
  • 批准号:
    9053241
  • 财政年份:
    2015
  • 资助金额:
    $ 84.8万
  • 项目类别:
10/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT SRI
10/21 ABCD-美国联盟:SRI 研究项目现场
  • 批准号:
    9981974
  • 财政年份:
    2015
  • 资助金额:
    $ 84.8万
  • 项目类别:
10/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT SRI
10/21 ABCD-美国联盟:SRI 研究项目现场
  • 批准号:
    10376294
  • 财政年份:
    2015
  • 资助金额:
    $ 84.8万
  • 项目类别:
Impact of the Coronavirus Pandemic on Alcohol Consumption and Mental Health in Young People
冠状病毒大流行对年轻人饮酒和心理健康的影响
  • 批准号:
    10171298
  • 财政年份:
    2012
  • 资助金额:
    $ 84.8万
  • 项目类别:
National Consortium on Alcohol and NeuroDevelopment in Adolescence - SRI International Research Project Site (NCANDA-SRI)
国家青少年酒精与神经发育联盟 - SRI 国际研究项目网站 (NCANDA-SRI)
  • 批准号:
    10471641
  • 财政年份:
    2012
  • 资助金额:
    $ 84.8万
  • 项目类别:

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