Impact of the Coronavirus Pandemic on Alcohol Consumption and Mental Health in Young People

冠状病毒大流行对年轻人饮酒和心理健康的影响

• 批准号: 10171298
• 负责人: Fiona C Baker
• 金额: $ 19.86万
• 依托单位: SRI INTERNATIONAL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-05 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10171298
• 关键词: Address; Adolescence; Adolescent; Adolescent and Young Adult; Adult; Affect; Age; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Amygdaloid structure; Anterior; Area; Behavior; Brain; Brain imaging; COVID-19; COVID-19 pandemic; Clinical; Clinical Data; Communicable Diseases; Complement; Complex; Containment; Coronavirus; Data; Data Reporting; Data Set; Development; Disasters; Disease; Disease Outbreaks; Distress; Dorsal; Economics; Event; Family; Feeling; Future; Grant; Guidelines; Health; Heavy Drinking; Hippocampus (Brain); Human; Individual; Intervention; Knowledge; Lead; Life; Link; Long-Term Effects; Machine Learning; Magnetic Resonance Imaging; Measures; Mental Depression; Mental Health; Moods; Morbidity - disease rate; Neurobiology; Outcome; Participant; Patient Self-Report; Personal Satisfaction; Phenotype; Physical activity; Population; Prefrontal Cortex; Public Health; Quarantine; Research; Risk; Risk Factors; Sampling; Shelter facility; Site; Social isolation; Social support; Societies; Socioeconomic Status; Surveys; Time; Uncertainty; United States National Institutes of Health; Well in self; Work; Youth; advanced analytics; adverse childhood events; alcohol availability; alcohol effect; alcohol exposure; alcohol risk; anxiety symptoms; behavioral economics; biological adaptation to stress; cingulate cortex; cohort; coping; coping mechanism; coronavirus disease; design; drinking; economic impact; experience; fear of falling; follow-up; high risk; longitudinal design; neurodevelopment; neuroimaging; news; pandemic disease; predictive signature; prevent; protective factors; psychiatric symptom; psychobiology; psychologic; psychological distress; public health intervention; resilience; response; sleep quality; social; traumatic stress

PROJECT SUMMARY / ABSTRACT The COVID-19 pandemic, best characterized as a disaster, is unprecedented in its impact on individuals, societies, and the economy. Of special consideration is the effect of the pandemic on the psychological wellbeing and behavior of young people. Here, we propose leveraging the longitudinal, multi-site National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) study (2012-2022) to investigate changes in wellbeing and behaviors, with a focus on alcohol use in response to the pandemic, in an established sample of young people including moderate-heavy users and those at risk for alcohol use, and to identify risk and protective factors for distress in response to the pandemic. Using NCANDA, we are able to directly address research objectives of NOSI NOT-OD-20-097 to understand social, behavioral and economic impacts from containment and mitigation efforts implemented to reduce spread of the COVID-19 disease, as well as downstream health impacts including substance use/abuse, and to determine risk and resiliency factors and outcomes. Unlike most research in this area, NCANDA includes neurobiological data critical to complement clinical and self-report data in understanding the complex and dynamic interactions leading up to and following a disaster. Also, with its accelerated longitudinal design and current age of participants spanning 17-28 years old, NCANDA is uniquely powered to disentangle age and pandemic related effects, unlike traditional same-age cohort designs. We propose supplementing the NCANDA project with a brief COVID-19 survey about alcohol use, mood, and other behaviors during the pandemic as well as COVID-19 exposure and pandemic-related distress, administered to participants in June 2020. To track long-term effects of the COVID-19 pandemic, the survey will be re-administered in Winter 2020 and Summer 2021. By embedding this survey, time-linked to the pandemic, within the existing NCANDA dataset, we propose characterizing the impact of the COVID-19 pandemic on alcohol use, mental health, and brain in young people (Aim 1) and to evaluate risk and resilience factors for COVID-19 pandemic-related distress (Aim 2). We propose using advanced analytics, including machine learning approaches, to identify a `signature' from the rich information captured by neuroimaging, clinical and self-report data prior to the COVID-19 pandemic, that predicts distress versus resilience in the face of the COVID-19 pandemic. A machine-learning approach embraces the complexity of the COVID-19 pandemic-related influence and takes advantage of the multi-domains within the NCANDA dataset. The analysis proposed in this supplement will offer valuable longitudinal data in a well-characterized sample of young people who are bridging developmental years into adulthood and that includes those at high risk for, or current heavy users of, alcohol. Such information can be used to guide public health and intervention strategies to benefit vulnerable young populations in the event of future disasters.

项目总结/摘要 COVID-19大流行，最好的描述是一场灾难，对个人的影响是前所未有的， 社会和经济。特别需要考虑的是大流行对心理健康的影响， 年轻人的行为。在这里，我们建议利用纵向，多站点的国家联盟， 酒精和青少年神经发育（NCANDA）研究（2012-2022），以调查 健康和行为，重点是应对大流行的酒精使用，在一个既定的样本， 青年人，包括中度重度使用者和有饮酒风险的人，并确定风险和保护措施， 在应对这一流行病方面，使用NCANDA，我们能够直接解决研究 NOSI NOT-OD-20-097的目标是了解遏制措施的社会、行为和经济影响 为减少COVID-19疾病的传播以及下游健康而实施的缓解措施 影响，包括物质使用/滥用，并确定风险和弹性因素和结果。 与该领域的大多数研究不同，NCANDA包括对补充临床和 自我报告的数据，以了解复杂的和动态的相互作用，导致和发生灾难后。 此外，由于其加速纵向设计和目前参与者的年龄跨越17-28岁，NCANDA 与传统的同龄组设计不同， 我们建议在NCANDA项目中补充一项关于酒精使用、情绪和 大流行期间的其他行为以及COVID-19暴露和与大流行相关的痛苦， 于2020年6月向参与者发放。为了跟踪COVID-19大流行的长期影响，调查将 将在2020年冬季和2021年夏季重新管理。 通过在现有的NCANDA数据集中嵌入与大流行时间相关的调查，我们建议 描述COVID-19大流行对年轻人饮酒、心理健康和大脑的影响 (Aim 1）以及评估COVID-19大流行相关困境的风险和复原力因素（目标2）。我们提出 使用先进的分析方法，包括机器学习方法，从富人中识别“签名”， 在COVID-19大流行之前，通过神经成像、临床和自我报告数据捕获的信息， 面对COVID-19大流行的痛苦与恢复力。机器学习方法包括 COVID-19大流行相关影响的复杂性，并利用 NCANDA数据集。 本补充报告中提出的分析将在一个特征良好的样本中提供有价值的纵向数据， 正在将发育期过渡到成年期的年轻人，包括那些有高风险的人，或 现在酗酒的人这些信息可用于指导公共卫生和干预战略 以便在今后发生灾害时使易受伤害的年轻人受益。