New Strategies in Catalytic Organic Synthesis with Organoboron Reagents

有机硼试剂催化有机合成新策略

• 批准号: 10396989
• 负责人: JAMES Patrick MORKEN
• 金额: $ 56.34万
• 依托单位: BOSTON COLLEGE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10396989
• 关键词: Address; Coupling; Equipment; Natural Resources; Organic Synthesis; Process; Reagent; Research; Techniques; enantiomer; functional group; new technology

Project Summary. New functional group transformations can enable synthetic chemists to disconnect molecules in new ways, thereby enabling new synthesis strategies. Ideally such new technologies enable the synthesis of important molecules from untapped, perhaps more readily available, starting materials. The proposed research will extend our fruitful studies on catalytic diboration, catalytic cross-coupling, and catalytic boronate rearrangements to address important new stereoselective transformations. Our strategies are keenly focused on developing processes that are readily accessible to the end-user without specialized techniques, equipment, or materials.

项目总结。