Oncopathology Training Program

肿瘤病理学培训计划

• 批准号: 10023784
• 负责人: JON C. ASTER
• 金额: $ 33.1万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-04 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10023784
• 关键词: Training Programs

PROJECT SUMMARY This is a new application for a Ruth L. Kirschstein National Research Service Award Institutional Research Training Grant (T32) to train post-doctoral trainees in the field of oncopathology, defined broadly as research that seeks to improve our understanding of cancer pathogenesis and pathobiology, and in doing so provide the basis for the development of new approaches that improve cancer diagnosis, prognostication, and treatment. The overall goal of the Oncopathology Training Program (OTP) is to provide research training opportunities across the full spectrum of oncopathology research, from basic study of cancer pathogenesis using the tools of cell and molecular biology, genomics, proteomics, animal modeling, and bioinformatics, to translational research that involves the development and deployment of biomarker tests and the use of digital and computational pathology, approaches that are increasingly important in cancer research. The training program is designed to benefit the research career development of M.D. and M.D./Ph.D. trainees subsequent to their training in clinical and/or anatomic pathology, and Ph.D. trainees with educational backgrounds in computational fields interested in the emerging area of computational pathology. Support is requested for 4 postdoctoral trainees in years 1-2, and 5 trainees in years 3-5. The training program includes structured elements such as individual development plans, mentored research experiences, and customizable didactic training opportunities as well as workshops in grant writing, manuscript composition, and lab management. Each trainee will have Postdoctoral Advisory Committee comprised of the Program Director, primary research mentor, and one or more senior cancer researchers with relevant expertise that will review trainee progress, provide advice and constructive criticism, and serve as a review committee for external fellowship proposals. The OTP faculty includes 24 highly accomplished investigators, with extensive mentoring track records and substantial extramural grant support, who constitute a highly collaborative mentoring community whose expertise span a wide-range of multidisciplinary, oncopathology-relevant areas, including animal modeling of cancer, cancer immunology, cancer genomics, computational pathology and tissue imaging, cancer diagnostics, and translational cancer informatics. The OTP will also take advantage of the extensive complement of scientific and educational resources that are available at Brigham and Women’s Hospital (BWH), Harvard Medical School (HMS). and Dana Farber Cancer Institute (DFCI), including the NCI-funded Dana-Farber/Harvard Cancer Center.

项目概要 这是 Ruth L. Kirschstein 国家研究服务奖机构研究的新申请 培训补助金（T32），用于培训肿瘤病理学领域的博士后学员，广泛定义为研究 旨在提高我们对癌症发病机制和病理学的理解，并在此过程中提供 为开发改善癌症诊断、预测和治疗的新方法奠定基础。 肿瘤病理学培训计划 (OTP) 的总体目标是提供研究培训机会 涵盖全方位的肿瘤病理学研究，从使用以下工具进行癌症发病机制的基础研究 细胞和分子生物学、基因组学、蛋白质组学、动物建模和生物信息学，直至转化 研究涉及生物标志物测试的开发和部署以及数字和技术的使用 计算病理学，在癌症研究中越来越重要的方法。培训计划 旨在有利于医学博士和医学博士/博士的研究职业发展。其后的受训者 临床和/或解剖病理学培训，以及博士学位。具有以下教育背景的学员 对计算病理学新兴领域感兴趣的计算领域。请求支持 4 第1-2年有博士后培训生，第3-5年有5名培训生。培训计划包括结构化的 个人发展计划、指导研究经验和可定制的教学等要素 资助写作、稿件撰写和实验室管理方面的培训机会和研讨会。 每个实习生都会有由项目主任、初级研究人员组成的博士后咨询委员会 导师，以及一名或多名具有相关专业知识的高级癌症研究人员，将审查学员的进展， 提供建议和建设性批评，并担任外部奖学金提案的审查委员会。 OTP 教职人员包括 24 名卓有成就的研究人员，拥有广泛的指导记录和 大量的校外赠款支持，构成了一个高度协作的指导社区，其 专业知识涵盖广泛的多学科、肿瘤病理学相关领域，包括动物模型 癌症、癌症免疫学、癌症基因组学、计算病理学和组织成像、癌症 诊断和转化癌症信息学。 OTP 还将利用广泛的 布莱根妇女医院提供的科学和教育资源的补充 （BWH），哈佛医学院（HMS）。和达纳法伯癌症研究所 (DFCI)，包括 NCI 资助的 达纳法伯/哈佛大学癌症中心。