Research Training Program in ImmunoEngineering

摘要： -- 随着近几十年来免疫学和免疫治疗领域的蓬勃发展， 免疫学研究和临床中的药品、生物医学设备和生物材料 应用领域迅速扩大。因此，对训练有素的工程师的需求越来越大 开发有效的免疫疗法所需的量化技能以及翻译这些 工业方面的发展。免疫学是一门基础科学，有很多应用需要 转化为对患者生活的积极影响(例如，抗炎或免疫抑制药物，避免 移植排斥、用于癌症治疗的过继细胞疗法)。在这一领域工作的大多数公司 免疫工程聘请基础科学家，因为免疫学是一门基础科学，尽管它有很多 可翻译的应用程序，以便对患者的生活产生积极影响(例如，抗炎或 免疫抑制药物、避免移植排斥反应、用于癌症治疗的过继细胞疗法)。然而， 这些人既没有接受过工程学方面的培训，也没有接受过量化或系统方面的培训。相比之下， 在免疫工程领域工作的公司也聘请了工程师，但他们通常没有 免疫学培训。本申请中描述的培训计划旨在通过以下方式更好地装备工程师 在免疫学(以及工程学)方面对他们进行培训。通过这个免疫工程培训项目， 我们将培养一种新型的工程实习生，即能够应用工程原理并具备以下知识的人 免疫学将对疾病的新治疗方法产生影响，谁将填补现有的关键空白 进入当今劳动力大军的生物工程师。我们的培训计划将进一步为您提供专业的 发展和道德培训，使学员掌握重要的“软技能”，如项目和时间 管理、道德和对他们性格属性的个人洞察力，以使他们在领导中处于最佳地位 在免疫工程工业和研究方面的职位。

Abstract    With the burgeoning of the fields of immunology and immunotherapy in the last few decades, the use of pharmaceutical products, biomedical devices, and biomaterials in immunological research and clinical applications has rapidly expanded. Accordingly, there has been an increasing need for engineers trained with the quantitative skills necessary for developing effective immunotherapies and with the skills to translate these developments to industry. Immunology is a basic science that has a lot of applications that need to be translated to positively impact patients' lives (e.g. anti-inflammatory or immunosuppressive drugs, avoiding transplant rejection, adoptive cell therapy for cancer treatment). Most companies working in this area of ImmunoEngineering hire basic scientists since immunology is a basic science, albeit one that has a lot of applications amenable to translation in order to positively impact patients' lives (e.g. anti-inflammatory or immunosuppressive drugs, avoiding transplant rejection, adoptive cell therapy for cancer treatment). However, these individuals do not have training in engineering nor quantitative or systems perspectives. In contrast, engineers are also hired into companies that work in ImmunoEngineering areas, but often they do not have immunology training. The training program described in this application is aimed to better equip engineers by training them in immunology (as well as in engineering). Through this ImmunoEngineering training program, we will develop a new type of engineering trainee, one who can apply engineering principles with knowledge of immunology to make impacts on new treatments for disease and who will fill a critical gap in existing bioengineers entering today's work force. Our training program will furthermore provide professional development and ethics training to equip trainees with important “soft skills” such as project and time management, ethics and personal insight into their character attributes to best position them for leadership positions in ImmunoEngineering industry and research.