Integrated Research Facility at Fort Detrick
Integrated Research Facility at Fort Detrick
批准号:
10267572
负责人:
Connie Schmaljohn
金额:
$4061.71万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AfricaAnimal Disease ModelsAnimal ModelCOVID-19ClinicalClinical ResearchCollaborationsContainmentDisease OutbreaksEbola virusEmerging Communicable DiseasesEvaluationHamstersIndustrializationInternationalIntramural Research ProgramLaboratoriesLassa virusMedicalMedical ImagingMissionModelingMolecular VirologyNational Institute of Allergy and Infectious DiseaseNipah VirusOutcomePathogenesisPathologyPositioning AttributeResearchUnited States National Institutes of HealthVaccinesbasebiodefenseclinical imagingefficacy testingexperimental studyimaging capabilitiesimprovednonhuman primateresearch facilityresponsetool
中文摘要
在2020财年,临床研究部的综合研究机构通过已建立的核心能力,包括临床成像、病理学、分子病毒学、西非疫情应对、潜在埃博拉病毒、尼帕病毒和拉萨病毒对策的评估,继续支持大量学术、工业和NIH内部研究计划的合作者。国际癌症研究所还建立了新冠肺炎、非人灵长类动物和仓鼠动物模型,以支持对抗措施的有效性测试和发病机制实验。红外线成像能力为这些模型中的新冠肺炎进展提供了独特的定量读数。
英文摘要
In FY20, the Integrated Research Facility in the Division of Clinical Research has continued to support a large number of academic, industrial and NIH intramural research program collaborators through established core capabilities including clinical imaging, pathology, molecular virology, outbreak response in West Africa, evaluation of potential Ebola virus, Nipah virus, and Lassa virus countermeasures. The IRF also established COVID-19 nonhuman primate and hamster animal models to support countermeasure efficacy testing and pathogenesis experiments. The IRFs imaging capability has provided an unique, quantitative readout for COVID-19 progression in these models.
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会议论文
Preclinical Assessment of a Multi-Head Electroporation Device for Delivery of Bio
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批准号:8499148
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项目类别:
-
资助金额:$71.88万
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财政年份:2013
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负责人:Connie Schmaljohn
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依托单位:
Preclinical Assessment of a Multi-Head Electroporation Device for Delivery of Bio
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批准号:8649026
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项目类别:
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资助金额:$78.59万
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财政年份:2013
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负责人:Connie Schmaljohn
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依托单位:
Assessment of the Immunogenicity and Protective Efficacy of a Multiagent DNA Vacc
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批准号:7644658
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项目类别:
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资助金额:$37.51万
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财政年份:2009
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负责人:Connie Schmaljohn
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依托单位:
Assessment of the Immunogenicity and Protective Efficacy of a Multiagent DNA Vacc
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批准号:7938762
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项目类别:
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资助金额:$103.13万
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财政年份:2009
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负责人:Connie Schmaljohn
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依托单位:
Evaluation of COVID-19 antibody therapies
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批准号:10285866
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项目类别:
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资助金额:$5.41万
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财政年份:--
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负责人:Connie Schmaljohn
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依托单位:
Integrated Research Facility at Fort Detrick
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批准号:10914725
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项目类别:
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资助金额:$4248.05万
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财政年份:--
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负责人:Connie Schmaljohn
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依托单位:
Development of the golden Syrian hamster model of COVID-19
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批准号:10283148
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项目类别:
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资助金额:$9.46万
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财政年份:--
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负责人:Connie Schmaljohn
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依托单位:
Development of the Crab eating macaque model of COVID-19
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批准号:10285867
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项目类别:
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资助金额:$12.16万
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财政年份:--
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负责人:Connie Schmaljohn
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依托单位:
海外基金