Integrated Research Facility at Fort Detrick

德特里克堡综合研究设施

• 批准号: 10267572
• 负责人: Connie Schmaljohn
• 金额: $ 4061.71万
• 依托单位: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10267572
• 关键词: Africa; Animal Disease Models; Animal Model; COVID-19; Clinical; Clinical Research; Collaborations; Containment; Disease Outbreaks; Ebola virus; Emerging Communicable Diseases; Evaluation; Hamsters; Industrialization; International; Intramural Research Program; Laboratories; Lassa virus; Medical; Medical Imaging; Mission; Modeling; Molecular Virology; National Institute of Allergy and Infectious Disease; Nipah Virus; Outcome; Pathogenesis; Pathology; Positioning Attribute; Research; United States National Institutes of Health; Vaccines; base; biodefense; clinical imaging; efficacy testing; experimental study; imaging capabilities; improved; nonhuman primate; research facility; response; tool

In FY20, the Integrated Research Facility in the Division of Clinical Research has continued to support a large number of academic, industrial and NIH intramural research program collaborators through established core capabilities including clinical imaging, pathology, molecular virology, outbreak response in West Africa, evaluation of potential Ebola virus, Nipah virus, and Lassa virus countermeasures. The IRF also established COVID-19 nonhuman primate and hamster animal models to support countermeasure efficacy testing and pathogenesis experiments. The IRFs imaging capability has provided an unique, quantitative readout for COVID-19 progression in these models.

在2020财年，临床研究部的综合研究机构继续通过建立核心能力，包括临床成像，病理学，分子病毒学，西非疫情应对，评估潜在的埃博拉病毒，尼帕病毒和拉沙病毒对策，支持大量的学术，工业和NIH内部研究项目合作者。IRF还建立了COVID-19非人灵长类动物和仓鼠动物模型，以支持对抗措施的有效性测试和致病性实验。IRF成像能力为这些模型中的COVID-19进展提供了独特的定量读数。