Coordinating Unit for DiaComp

DiaComp 协调单位

• 批准号: 10257590
• 负责人: Richard A. MCINDOE
• 金额: $ 67.88万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-05 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10257590
• 关键词: Agreement; Animal Model; Area; Award; Businesses; Collaborations; Communication; Communities; Complications of Diabetes Mellitus; Computer Hardware; Computer software; Data; Development; E-learning; Educational workshop; Environment; Evaluation; Feedback; Fostering; Funding; General Population; Goals; Infrastructure; Laboratories; Maintenance; Modeling; National Institute of Diabetes and Digestive and Kidney Diseases; Occupational activity of managing finances; Pilot Projects; Process; Records; Reporting; Research; Research Personnel; Research Support; Services; System; Teleconferences; Training; Travel; Visualization software; analytical tool; design; informatics infrastructure; meetings; member; operation; phenotypic data; programs; software systems; success; symposium; web portal; web site; web-based tool

Over the last 16 years, our group has successfully managed the coordinating unit (CU) for the NIDDK funded Diabetic Complications Consortium (DiaComp 2001-present, formerly the Animal Models of Diabetic Complications Consortium). DiaComp provides an environment to foster communications and collaborations between investigator communities involved in diabetic complications research. Toward this goal, DiaComp sponsors annual meetings in complications-relevant scientific areas, solicits and funds pilot projects in high impact areas of complications research, and supports a website to serve the diabetic complications community. During the previous five year funding cycle, the CU was responsible for continuing support for DiaComp through the use of opportunity pools (funding), manage/maintain the website and phenotyping data and administratively organize the meetings and workshops sponsored by the DiaComp to engage the greater diabetic complications scientific community. Our laboratory has been the CU for DiaComp for the last 16 years. The CU is responsible for creating and maintaining the administrative, scientific and informatics infrastructure necessary to organize and facilitate consortial operations. The goal of this proposal is to provide that infrastructure. We will build upon the success of the current DiaComp CU infrastructure to provide DiaComp with a robust and comprehensive service oriented solution that supports the unique aspects of this consortium.

在过去的16年中，我们的小组已成功管理了NIDDK资助的协调单元（CU） 糖尿病并发症财团（DIACOMP 2001-至今，以前是糖尿病的动物模型 并发症财团）。 DIACOMP提供了一个促进通信和协作的环境 研究人员之间参与糖尿病并发症研究的社区。达到这个目标，迪亚姆普 赞助与并发症相关的科学领域，征集和资金的年度会议 影响并发症研究的领域，并支持网站为糖尿病并发症服务 社区。在过去的五年资金周期中，CU负责继续支持 DIACOMP通过使用机会池（资金），管理/维护网站和表型数据 并在行政上组织DIACOMP赞助的会议和研讨会，以吸引更多 糖尿病并发症科学界。我们的实验室一直是最后16次DIACOMP的CU 年。 CU负责创建和维护行政，科学和信息学 组织和促进联盟业务所需的基础设施。该提议的目的是提供 那个基础设施。我们将基于当前DIACOMP CU基础架构提供的成功 DIACOMP具有强大而全面的面向服务的解决方案，以支持其独特方面 财团。

项目成果

Thoracic Spinal Nerve Neuromodulation Therapy for Diabetic Gastroparesis: A Proof-of-Concept Study.

• DOI: 10.1016/j.cgh.2022.09.012
• 发表时间: 2023-10
• 期刊: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Botulinum Injection Into the Proximal Intestinal Wall of Diet-Induced Obese Mice Leads to Weight Loss and Improves Glucose and Fat Tolerance.

将肉毒杆菌注射到饮食引起的肥胖小鼠的近端肠壁可导致体重减轻并改善葡萄糖和脂肪耐受性。

• DOI: 10.2337/db21-0708
• 发表时间: 2022
• 期刊: Diabetes
• 影响因子: 7.7
• 作者: Sundaresan,Sinju;Antoun,Joseph;Banan,Babak;Adcock,Jamie;Johnson,Connor;Claire,Brendan;Dixon,Kala;Flynn,Joyce;Shibao,CyndyaA;Abumrad,Naji
• 通讯作者: Abumrad,Naji

Constitutive LH receptor activity impairs NO-mediated penile smooth muscle relaxation.

• DOI: 10.1530/rep-20-0447
• 发表时间: 2021-01
• 期刊: Reproduction (Cambridge, England)
• 作者: Hiremath DS;Priviero FBM;Webb RC;Ko C;Narayan P
• 通讯作者: Narayan P

Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics.

• DOI: 10.1186/s40168-022-01436-3
• 发表时间: 2023-03-15
• 期刊: Microbiome
• 影响因子: 15.5

Chronic Unpredictable Stress Impairs the Reactivity of the Pudendal Artery and Corpus Cavernosum in Male Mice.

慢性不可预测的压力会损害雄性小鼠阴部动脉和海绵体的反应性。

• 发表时间: 2022
• 期刊: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
• 作者: Priviero,Fernanda;Arishe,Olufunke;Wilczynski,Stephanie;Crockett,Alexia;Hollis,Fiona;Webb,Clinton
• 通讯作者: Webb,Clinton