Center for Pediatric Brain Health

儿科脑健康中心

• 批准号: 10580767
• 负责人: Tony W Wilson
• 金额: $ 243.06万
• 依托单位: FATHER FLANAGAN'S BOYS' HOME
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-01 至 2027-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10580767
• 关键词: Acceleration; Advisory Committees; Area; Brain; Centers of Research Excellence; Child; Child Care; Childhood; Cognitive; Collaborations; Collection; Communities; Community Health; Community Outreach; Computers and Advanced Instrumentation; Core Facility; Development; Educational workshop; Ensure; Equipment; Evaluation; Event; Extramural Activities; Faculty; Family; Fostering; Funding; Future Generations; Future Teacher; Goals; Growth; Health; Home; Hospitals; Human; Image; Imaging technology; Infrastructure; Institution; Internships; Lead; Magnetic Resonance Imaging; Magnetoencephalography; Mentors; Methods; Mission; Monitor; National Institute of General Medical Sciences; Nebraska; Neurosciences; Neurosciences Research; Participant; Pilot Projects; Population; Postdoctoral Fellow; Publications; Publishing; Registries; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Scientist; Senior Scientist; Series; Site; Structure; System; Training; Training Programs; Training and Education; Voice; Work; boys; brain health; career; career development; cohort; collaborative environment; experience; graduate student; improved; innovation; instrumentation; multidisciplinary; multimodal neuroimaging; neural; neuroimaging; neuroregulation; next generation; novel; outreach; prisma; programs; research and development; square foot; training opportunity; welfare

Abstract/Summary: Overall Component This application for a Center of Biomedical Research Excellence (COBRE) would initiate a Center for Pediatric Brain Health to manage, support, and expand developmental neuroimaging and pediatric neuroscience research at Boys Town National Research Hospital (BTNRH) in Omaha, Nebraska. It is an opportune moment for pediatric neuroscience at BTNRH, as an organization-wide initiative to expand in this area has resulted in numerous faculty hires and the construction of a new state-of-the-art 15,000+ square feet Institute for Human Neuroscience. The proposed Center for Pediatric Brain Health will organize and support these new resources under a central umbrella, and provide critical programs to help grow the community and build cohesiveness around a common theme of pediatric neuroscience and brain health. The key components of the Center include an Administrative Core, one research core (i.e., the Neural Quantification & Imaging Core), four research project leaders (RPLs), a Supervisory & Mentoring Committee, and a cohort of established pediatric neuroscientists. Upon initiation of the Center, the Administrative Core will implement a comprehensive research support structure that includes mentoring and career developing resources, a pilot projects program, extensive training opportunities, two distinct seminar series, community outreach, and broad support of key research infrastructure (e.g., participant registry, shared research spaces). Training opportunities will include technical workshops, as well as internships and a postdoctoral neuroimaging training program for fostering the next generation of graduate students and Center faculty. In parallel, the Administrative Core will promote the launch of four RPLs and implement a career development and evaluation system, which will include a Supervisory & Mentoring Committee comprised of 10 senior scientists who will monitor progress and ensure each RPL and their two co-mentors reach critical milestones. Finally, the new Neural Quantification & Imaging Core will support and provide direct access to state- of-the-art instrumentation for pediatric neuroimaging, including a new 3-Tesla Siemens Prisma magnet, two Neo magnetoencephalographic (MEG) imaging units, a mock MRI scanner, and other major equipment, and will provide comprehensive analytical support for the most advanced neuroimaging analyses currently available. Notably, the Core will be the only site in the world to host two MEG Neo systems for quantifying human brain dynamics. The new Center will also support a cohort of senior scientists with expertise spanning multiple pediatric populations and different imaging technologies. Finally, the Center will receive exceptional institutional support, including funds for pilot projects, Core staffing, internships, major equipment expenses, and other initiatives, and will be directed by Dr. Tony Wilson who is a developmental cognitive neuroscientist with extensive experience in multimodal neuroimaging and an exceptional track record of extramural support, publications, and mentoring. Taken together, the expansive resources, support, and expertise within the new Center for Pediatric Brain Health will ensure that it has a major long-term impact on pediatric neuroscience research at BTNRH and beyond.

摘要/摘要：总体组件 生物医学研究卓越中心(Cobre)的申请将启动儿科研究中心 大脑健康管理、支持和扩展发育神经成像和儿科神经科学研究 在内布拉斯加州奥马哈的男孩镇国立研究医院(BTNRH)。对于儿科医生来说，这是一个好时机 BTNRH的神经科学，作为组织范围内在这一领域扩展的倡议，已经导致了许多 招聘教员，并建造一座新的最先进的15,000多平方英尺的人类神经科学研究所。 拟议的儿科脑健康中心将在一个中央项目下组织和支持这些新资源 保护伞，并提供关键计划，以帮助发展社区并围绕共同的 儿科神经科学和脑健康主题。该中心的主要组成部分包括行政部门 核心，一个研究核心(即，神经量化和成像核心)，四个研究项目负责人(RPL)， 一个监督和指导委员会，以及一群公认的儿科神经学家。在启动时 该中心的行政核心将实施一个全面的研究支持结构，包括 指导和职业发展资源，一个试点项目方案，广泛的培训机会，两个 独特的研讨会系列、社区推广和关键研究基础设施的广泛支持(例如，参与者 登记处、共享研究空间)。培训机会将包括技术讲习班和实习。 和博士后神经成像培训计划，培养下一代研究生和 中心教职员工。同时，行政核心将推动推出四个区域工作方案，并实施一项职业 发展和评价系统，其中将包括一个由10人组成的监督和指导委员会 高级科学家将监测进展，并确保每个RPL和他们的两名共同导师达到关键 里程碑。最后，新的神经量化和成像核心将支持并提供对状态的直接访问- 最先进的儿科神经成像仪器，包括新的3特斯拉西门子Prisma磁铁，Two Neo 脑磁图(MEG)成像装置、模拟核磁共振扫描仪和其他主要设备，并将 为目前可用的最先进的神经成像分析提供全面的分析支持。 值得注意的是，核心将是世界上唯一一个拥有两个MEG Neo系统的地点，用于量化人类大脑 动力学。新中心还将支持一批拥有跨多个儿科专业知识的资深科学家 人群和不同的成像技术。最后，该中心将得到特殊的机构支持， 包括用于试点项目、核心人员编制、实习、主要设备费用和其他倡议的资金，以及 将由托尼·威尔逊博士指导，他是一位具有丰富经验的发展认知神经科学家 在多模式神经成像方面，以及在外部支持、出版物和指导方面的出色记录。 总而言之，新的儿科脑健康中心内的广泛资源、支持和专业知识 将确保它对BTNRH和其他地方的儿科神经科学研究产生重大的长期影响。