Characterizing and modulating neurocognitive processes of learning to trust and distrust in aging
表征和调节衰老过程中学习信任和不信任的神经认知过程
基本信息
- 批准号:10622831
- 负责人:
- 金额:$ 12.32万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-03-01 至 2027-04-30
- 项目状态:未结题
- 来源:
- 关键词:AdultAgeAgingBehavioralClinicalCognitiveComputer ModelsCuesDataData AnalysesDecision MakingDisadvantagedElderlyFundingGoalsHispanicIndividualInstitutionLatinaLearningLongevityMentorsNeurocognitiveNeurosciencesPopulationProcessPsychological reinforcementResearchResearch PersonnelSamplingScienceSiteStatistical Data InterpretationTrainingTrustWomanWorkWritingcareercareer developmentchronic painclassical conditioningclinical paindisadvantaged backgrounddistrustneural circuitneuroimagingparent grantresearch and developmentskillssocialtrustworthiness
项目摘要
Project Summary (Supplement). This supplement aims to bring Dr. Marilyn Horta, who is from an
underrepresented background in the sciences at our institution and in the US, to work under the parent grant
R01AG072658. This project offers an ideal context for Dr. Horta's research and career development given her
goals of becoming an independent, productive researcher in aging and decision neuroscience. Dr. Horta would
have the opportunity to (i) expertise in the identification and optimization of neurocognitive processes of learning
to trust and distrust in particularly vulnerable and currently understudied older adult populations (i.e., individuals
with chronic pain; disadvantaged groups); (ii) skills in advanced statistical analysis of behavioral and
neuroimaging data; and (iii) enhanced presentation and academic writing abilities. Dr. Horta will work closely
with her mentoring team that spans across the three parent grant sites and includes balanced expertise in in
cognitive and socioemotional experimental aging and neuroimaging analysis (Dr. Ebner), computational
modeling of reinforcement and learning (Dr. Wilson), decision neuroscience (Dr. Lighthall), and clinical pain and
aging (Dr. Fillingim). On her initiative, Dr. Horta has successfully obtained pilot funding to investigate decision
making among older adults with chronic pain, a particularly vulnerable and currently understudied older adult
group regarding trust-related decision making. Integrating her clinical expertise in chronic pain populations under
the parent grant, Dr. Horta will significantly contribute to all three parent grant aims. In particular, she will advance
Aim 1, which is to confirm age deficits in learning to trust in an adult lifespan sample and determine the extent
to which social cues of trustworthiness bias trust-related decisions and learning in older adults, by differentiating
chronic pain status among the parent grant sample; and with her newly learned skills in computational modeling
under the supplement will be able to isolate specific learning biases (e.g., social cue, loss aversion, and recency)
under consideration of chronic pain status. Further, Dr. Horta's training in advanced neuroimaging data analysis
will directly contribute to Aim 2, which seeks to confirm altered neurocircuitry underlying age-associated learning
deficits; again, extending this work to chronic pain. Finally, findings from the analyses under Aims 1 and 2 will
directly inform Aim 3 toward identifying the best target for training the malleability of the neurocircuitry underlying
trust-learning deficits in vulnerable older adults.
项目摘要(补充)。本增刊的目的是把玛丽莲·奥尔塔博士,谁是从一个
在我们的机构和美国,在科学方面代表性不足的背景,在父母资助下工作
R01AG072658。这个项目为Horta博士的研究和职业发展提供了一个理想的背景,
目标是成为一个独立的,富有成效的研究人员在老化和决策神经科学。奥尔塔医生
有机会(i)识别和优化学习的神经认知过程的专业知识
信任和不信任特别脆弱和目前研究不足的老年人群体(即,个人
慢性疼痛;弱势群体);(ii)行为和行为的高级统计分析技能,
神经成像数据;和(iii)增强的演示和学术写作能力。奥尔塔博士将与
与她的指导团队,跨越三个母公司赠款网站,并包括平衡的专业知识,在
认知和社会情绪实验老化和神经影像分析(Ebner博士),计算
强化和学习建模(威尔逊博士),决策神经科学(莱特霍尔博士),临床疼痛和
老化(Fillingim博士)。在她的倡议下,Horta博士成功地获得了试点资金,
在患有慢性疼痛的老年人中,
与信任相关的决策。将她在慢性疼痛人群中的临床专业知识
父母补助金,博士奥尔塔将大大有助于所有三个父母补助金的目标。特别是,她将提前
目的1,这是为了证实年龄缺陷,在学习信任的成年人寿命样本,并确定程度
值得信赖的社会线索偏见与信任有关的决策和学习在老年人中,通过区分
慢性疼痛状态的父母补助金样本;并与她新学到的技能,在计算建模
在补充下将能够隔离特定的学习偏差(例如,社会线索、损失厌恶和近因)
考虑到慢性疼痛状态。此外,Horta博士在高级神经成像数据分析方面的培训
将直接有助于目标2,该目标旨在确认与年龄相关的学习背后的神经回路改变
赤字;再次,将这项工作扩展到慢性疼痛。最后,目标1和2下的分析结果将
直接告知目标3,以确定训练神经回路基础延展性的最佳目标,
脆弱的老年人的信任学习缺陷。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Natalie C Ebner其他文献
305 - High Impact Knee Pain Moderates the Relationship Between Interoceptive Sensitivity and Resting State Functional Connectivity Within the Salience Network
305 - 高冲击性膝关节疼痛调节显著性网络内的内脏敏感性与静息状态功能连接之间的关系
- DOI:
10.1016/j.jpain.2025.105103 - 发表时间:
2025-04-01 - 期刊:
- 影响因子:4.000
- 作者:
Alejandro Dorado;Pedro Antonio Valdés-Hernández;Soamy Montesino-Goicolea;Larissa J Strath;Kristina Bell;Ana María González-Roldán;Natalie C Ebner;Yenisel Cruz-Almeida - 通讯作者:
Yenisel Cruz-Almeida
Natalie C Ebner的其他文献
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{{ truncateString('Natalie C Ebner', 18)}}的其他基金
Characterizing and modulating neurocognitive processes of learning to trust and distrust in aging
表征和调节衰老过程中学习信任和不信任的神经认知过程
- 批准号:
10827596 - 财政年份:2022
- 资助金额:
$ 12.32万 - 项目类别:
Characterizing and modulating neurocognitive processes of learning to trust and distrust in aging
表征和调节衰老过程中学习信任和不信任的神经认知过程
- 批准号:
10365569 - 财政年份:2022
- 资助金额:
$ 12.32万 - 项目类别:
Characterizing and modulating neurocognitive processes of learning to trust and distrust in aging
表征和调节衰老过程中学习信任和不信任的神经认知过程
- 批准号:
10576379 - 财政年份:2022
- 资助金额:
$ 12.32万 - 项目类别:
Uncovering and Surveilling Financial Deception Risk in Aging
发现和监控老龄化过程中的财务欺诈风险
- 批准号:
10210345 - 财政年份:2018
- 资助金额:
$ 12.32万 - 项目类别:
Uncovering and Surveilling Financial Deception Risk in Aging
发现和监控老龄化过程中的财务欺诈风险
- 批准号:
10448338 - 财政年份:2018
- 资助金额:
$ 12.32万 - 项目类别:
Uncovering and Surveilling Financial Deception Risk in Aging
发现和监控老龄化过程中的财务欺诈风险
- 批准号:
10645913 - 财政年份:2018
- 资助金额:
$ 12.32万 - 项目类别:
Uncovering and Surveilling Financial Deception Risk in Aging (Diversity Supplement to 1R01AG057764-01A1)
发现和监控老龄化过程中的财务欺诈风险(1R01AG057764-01A1 的多样性补充)
- 批准号:
10205821 - 财政年份:2018
- 资助金额:
$ 12.32万 - 项目类别:
Uncovering and Surveilling Financial Deception Risk in Aging
发现和监控老龄化过程中的财务欺诈风险
- 批准号:
9766171 - 财政年份:2018
- 资助金额:
$ 12.32万 - 项目类别:
Uncovering and Surveilling Financial Deception Risk in Aging - Alzheimer's Disease Supplement
发现和监测老龄化过程中的财务欺诈风险 - 阿尔茨海默氏病补充剂
- 批准号:
10286756 - 财政年份:2018
- 资助金额:
$ 12.32万 - 项目类别:
Uncovering and Surveilling Financial Deception Risk in Aging
发现和监控老龄化过程中的财务欺诈风险
- 批准号:
10440656 - 财政年份:2018
- 资助金额:
$ 12.32万 - 项目类别:
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