Developmental Biology Training Program

发育生物学培训计划

• 批准号: 10627560
• 负责人: Kristen M Kwan
• 金额: $ 39.69万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-29 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627560
• 关键词: Developmental Biology; Training Programs

PROJECT SUMMARY / ABSTRACT (30 Lines of text) Developmental biology, an interdisciplinary science at the leading edge of modern biomedical research, integrates stem-cell and molecular biology, genetics, biochemistry and whole-animal model systems. This Developmental Biology Training Grant (DBTG) application requests support for eight predoctoral and three postdoctoral trainees in an interdepartmental Developmental Biology Training Program, consisting of individualized research training under the guidance of 48 faculty members in nine PhD degree-granting departments at the University of Utah. The Internal Advisory Board (IAB) selects Trainees through a formal application process and NIH study section-style review. Predoctoral Trainees who have completed their qualifying exams in the Biosciences Programs or the MD/PhD Program are supported for up to two years, and Postdoctoral Trainees are also supported for up to two years. Both groups are selected from a highly competitive pool, based on excellence in previous research, a research proposal, and letters of recommendation. Trainees will be mentored to apply for individual F30/F31/F32 fellowships or other nationally competitive awards to enhance their career development. Success for Predoctoral Fellows will be measured by by successful individual fellowship awards, PhD graduation, and obtaining their next step professional advancement (typically postdoctoral positions). Success for Postdoctoral Fellows will be measured by next step professional advancement, typically faculty positions or leadership positions in biotech or other biomedical research programs. MPIs stay in touch with former trainees and continue to serve as career advisors. This Program uses ten mechanisms for value-added training of these carefully chosen and especially competitive Predoctoral and Postdoctoral Trainees: twice-monthly Developmental Biology Discussion Group meetings; didactic coursework focused on Developmental Biology and science ethics; DBTG Sponsored Seminars; experience in hosting visitors and national Symposia; funding and preparation for Trainee presentations at national scientific conferences; training in the effective utilization of Predoctoral and Postdoctoral Individual Development Plans (IDPs); unique Postdoctoral Mentoring committees that add significant guidance to each Postdoctoral Trainee’s career development; an innovative Mentor-the-Mentor program that enhances the faculty’s ability to mentor Trainees; opportunities for Grant/Fellowship Writing Workshops; and a highly successful DBTG Annual Retreat. The Program actively solicits and implements recommendations from Trainees, Mentors, IAB and External Advisory Board (EAB). With leading researchers in multiple model organisms, this Program has an exceptional track record of training predoctoral and postdoctoral scientists in the interdisciplinary field of Developmental Biology and preparing them to direct their own first-rate independent research programs.

项目总结/摘要（30行文本） 发育生物学是现代生物医学研究的前沿交叉学科， 整合了干细胞和分子生物学、遗传学、生物化学和整个动物模型系统。这 发育生物学培训补助金（DBTG）申请要求支持八个博士前和三个 博士后学员在跨部门的发育生物学培训计划，包括 在9个博士学位授予点的48名教师的指导下进行个性化研究培训 在犹他州大学的系。内部咨询委员会（IAB）通过正式的 申请过程和NIH研究部分风格的审查。已完成学业的博士前培训生 生物科学课程或MD/PhD课程的资格考试支持长达两年， 博士后培训生也支持长达两年。这两组都是从一个高度 竞争力的游泳池，在以前的研究，研究建议，和信件的基础上卓越 推荐学员将被指导申请个人F30/F31/F32奖学金或其他国家奖学金。 有竞争力的奖项，以促进他们的职业发展。博士前研究员的成功将通过以下方式衡量： 通过成功的个人奖学金，博士毕业，并获得他们的下一步专业 博士后（Postdoctoral）。博士后研究员的成功将由下一个衡量 阶梯式专业晋升，通常是生物技术或其他生物医学领域的教师职位或领导职位 研究项目。MPI与以前的学员保持联系，并继续担任职业顾问。 该计划使用十种机制，对这些精心挑选的，特别是 有竞争力的博士前和博士后学员：每月两次的发育生物学讨论组 会议;教学课程侧重于发育生物学和科学伦理学; DBTG赞助 研讨会;接待来访者和国家专题讨论会的经验;培训人员的供资和准备 在国家科学会议上的演讲;有效利用博士前和博士后研究生的培训; 博士后个人发展计划（IDPs）;独特的博士后指导委员会， 对每位博士后研究生的职业发展提供重要指导;创新的导师 提高教师指导学员能力的计划;赠款/奖学金写作的机会 工作坊;和一个非常成功的DBTG年度务虚会。《方案》积极征集实施 学员、导师、IAB和外部咨询委员会（EAB）的建议。 该计划拥有多个模式生物的领先研究人员，具有出色的培训记录 博士前和博士后科学家在发展生物学的跨学科领域，并准备 他们指导自己一流的独立研究项目。

项目成果

Muscle stem cells contribute to myofibres in sedentary adult mice.

• DOI: 10.1038/ncomms8087
• 发表时间: 2015-05-14
• 期刊: NATURE COMMUNICATIONS
• 影响因子: 16.6
• 作者: Keefe, Alexandra C.;Lawson, Jennifer A.;Flygare, Steven D.;Fox, Zachary D.;Colasanto, Mary P.;Mathew, Sam J.;Yandell, Mark;Kardon, Gabrielle
• 通讯作者: Kardon, Gabrielle

The long and winding road to the mitochondrial pyruvate carrier.

• DOI: 10.1186/2049-3002-1-6
• 发表时间: 2013-01-23
• 期刊: Cancer & metabolism
• 影响因子: 5.9
• 作者: Schell JC;Rutter J
• 通讯作者: Rutter J

Parallel Evolution of Sperm Hyper-Activation Ca2+ Channels.

• DOI: 10.1093/gbe/evx131
• 发表时间: 2017-07-01
• 期刊: Genome biology and evolution
• 影响因子: 3.3
• 作者: Cooper JC;Phadnis N
• 通讯作者: Phadnis N

Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterranea.

• DOI: 10.1016/j.stem.2008.07.002
• 发表时间: 2008-09-11
• 期刊: CELL STEM CELL
• 影响因子: 23.9
• 作者: Eisenhoffer, George T.;Kang, Hara;Alvarado, Alejandro Sanchez
• 通讯作者: Alvarado, Alejandro Sanchez

Examining Hippocampal Mossy Fiber Synapses by 3D Electron Microscopy in Wildtype and Kirrel3 Knockout Mice.

• DOI: 10.1523/eneuro.0088-17.2017
• 发表时间: 2017-05
• 期刊: eNeuro
• 影响因子: 3.4
• 作者: Martin EA;Woodruff D;Rawson RL;Williams ME
• 通讯作者: Williams ME