Developmental Biology Training Program

发育生物学培训计划

• 批准号: 10627560
• 负责人: Kristen M Kwan
• 金额: $ 39.69万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-29 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627560
• 关键词: Developmental Biology; Training Programs

PROJECT SUMMARY / ABSTRACT (30 Lines of text) Developmental biology, an interdisciplinary science at the leading edge of modern biomedical research, integrates stem-cell and molecular biology, genetics, biochemistry and whole-animal model systems. This Developmental Biology Training Grant (DBTG) application requests support for eight predoctoral and three postdoctoral trainees in an interdepartmental Developmental Biology Training Program, consisting of individualized research training under the guidance of 48 faculty members in nine PhD degree-granting departments at the University of Utah. The Internal Advisory Board (IAB) selects Trainees through a formal application process and NIH study section-style review. Predoctoral Trainees who have completed their qualifying exams in the Biosciences Programs or the MD/PhD Program are supported for up to two years, and Postdoctoral Trainees are also supported for up to two years. Both groups are selected from a highly competitive pool, based on excellence in previous research, a research proposal, and letters of recommendation. Trainees will be mentored to apply for individual F30/F31/F32 fellowships or other nationally competitive awards to enhance their career development. Success for Predoctoral Fellows will be measured by by successful individual fellowship awards, PhD graduation, and obtaining their next step professional advancement (typically postdoctoral positions). Success for Postdoctoral Fellows will be measured by next step professional advancement, typically faculty positions or leadership positions in biotech or other biomedical research programs. MPIs stay in touch with former trainees and continue to serve as career advisors. This Program uses ten mechanisms for value-added training of these carefully chosen and especially competitive Predoctoral and Postdoctoral Trainees: twice-monthly Developmental Biology Discussion Group meetings; didactic coursework focused on Developmental Biology and science ethics; DBTG Sponsored Seminars; experience in hosting visitors and national Symposia; funding and preparation for Trainee presentations at national scientific conferences; training in the effective utilization of Predoctoral and Postdoctoral Individual Development Plans (IDPs); unique Postdoctoral Mentoring committees that add significant guidance to each Postdoctoral Trainee’s career development; an innovative Mentor-the-Mentor program that enhances the faculty’s ability to mentor Trainees; opportunities for Grant/Fellowship Writing Workshops; and a highly successful DBTG Annual Retreat. The Program actively solicits and implements recommendations from Trainees, Mentors, IAB and External Advisory Board (EAB). With leading researchers in multiple model organisms, this Program has an exceptional track record of training predoctoral and postdoctoral scientists in the interdisciplinary field of Developmental Biology and preparing them to direct their own first-rate independent research programs.

项目摘要 /摘要（文本30行） 发展生物学，现代生物医学研究领先地位的跨学科科学， 整合干细胞和分子生物学，遗传学，生物化学和全动物模型系统。这 发育生物学培训赠款（DBTG）申请要求支持八个五次和三个 部门间发育生物学培训计划中的博士后学员，由 在九个博士学位授予的48位教职员工的指导下的个性化研究培训 犹他大学系。内部顾问委员会（IAB）通过以前的 申请过程和NIH研究部分式审查。完成了他们的前学员 在Biosciences计划或MD/PHD计划中的合格考试长达两年，并且 博士后学员也得到了长达两年的支持。两组都是从高度选择的 竞争池，基于先前研究的卓越，一项研究建议和信件 推荐。学员将被认为申请单独的F30/F31/F32奖学金或其他全国性的奖学金 竞争性奖励以增强他们的职业发展。托管前研究员的成功将由 通过成功的个人奖学金奖，博士毕业并获得下一步专业人士 进步（通常是博士后职位）。博士后研究员的成功将在接下来衡量 步骤专业的进步，通常是生物技术或其他生物医学的教师职位或领导职位 研究计划。 MPI与以前的培训保持联系，并继续担任职业顾问。 该程序使用十种机制来增值这些精心选择的培训，尤其是 竞争性和博士后学员：每月两次发育生物学讨论小组 会议；教学课程的重点是发展生物学和科学伦理； DBTG赞助 研讨会；有接待游客和国家研讨会的经验；学员的资金和准备 在国家科学会议上演讲；在有效利用前的培训和 博士后个人发展计划（IDP）；独特的博士后指导委员会添加 每个博士后学员的职业发展的重要指导；创新的导师 提高教师对心理学生的能力的计划；授予/奖学金写作的机会 讲习班；以及非常成功的DBTG年度务虚会。该计划积极固体和工具 受训人员，导师，IAB和外部顾问委员会（EAB）的建议。 在多种模型生物中的领先研究人员的情况下，该计划具有培训的出色记录 发育生物学跨学科领域和准备 他们指导自己的一流独立研究计划。

项目成果

Muscle stem cells contribute to myofibres in sedentary adult mice.

• DOI: 10.1038/ncomms8087
• 发表时间: 2015-05-14
• 期刊: NATURE COMMUNICATIONS
• 影响因子: 16.6
• 作者: Keefe, Alexandra C.;Lawson, Jennifer A.;Flygare, Steven D.;Fox, Zachary D.;Colasanto, Mary P.;Mathew, Sam J.;Yandell, Mark;Kardon, Gabrielle
• 通讯作者: Kardon, Gabrielle

Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterranea.

• DOI: 10.1016/j.stem.2008.07.002
• 发表时间: 2008-09-11
• 期刊: CELL STEM CELL
• 影响因子: 23.9
• 作者: Eisenhoffer, George T.;Kang, Hara;Alvarado, Alejandro Sanchez
• 通讯作者: Alvarado, Alejandro Sanchez

Examining Hippocampal Mossy Fiber Synapses by 3D Electron Microscopy in Wildtype and Kirrel3 Knockout Mice.

• DOI: 10.1523/eneuro.0088-17.2017
• 发表时间: 2017-05
• 期刊: eNeuro
• 影响因子: 3.4
• 作者: Martin EA;Woodruff D;Rawson RL;Williams ME
• 通讯作者: Williams ME

Parallel Evolution of Sperm Hyper-Activation Ca2+ Channels.

• DOI: 10.1093/gbe/evx131
• 发表时间: 2017-07-01
• 期刊: Genome biology and evolution
• 影响因子: 3.3
• 作者: Cooper JC;Phadnis N
• 通讯作者: Phadnis N

The long and winding road to the mitochondrial pyruvate carrier.

• DOI: 10.1186/2049-3002-1-6
• 发表时间: 2013-01-23
• 期刊: Cancer & metabolism
• 影响因子: 5.9
• 作者: Schell JC;Rutter J
• 通讯作者: Rutter J