14/24 The Healthy Brain & Child Development National Consortium

14/24 健康的大脑

• 批准号: 10757271
• 负责人: Gretchen E. Bandoli
• 金额: $ 5.69万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10757271
• 关键词: Admission activity; Behavior; Birth; Brain; California; Categories; Censuses; Child; Child Development; Country; Data; Data Analyses; Data Collection; Development; Exposure to; Goals; Health; Immigrant; Infant; Infant Health; Life; Literature; Maternal Health; Maternal and Child Health; Mental Health; Mentors; Middle East; Middle Eastern; Mothers; North African; Outcome; Perinatal; Perinatal Epidemiology; Population; Pregnancy; Refugees; Research; Research Personnel; Sampling; Site; Training; Underrepresented Populations; Underserved Population; United States; United States National Institutes of Health; Universities; Woman; Work; career; career development; cohort; cultural competence; design; equity, diversity, and inclusion; experience; infant outcome; marginalized population; maternal outcome; parent grant; perinatal health; recruit; research and development; response; substance use; working group

This Diversity Supplement will be nested in the Healthy Brain and Child Development National Consortium (HBCD-NC) study at the University of California San Diego (UCSD) site (U01DA055369 contact MPI: Bandoli). The overall goal of the parent grant is to develop a normative template of brain development in response to various exposures across the first ten years of life. To achieve this, NIH has selected UCSD and 25 other sites across the United States (US) to recruit and follow a diverse and representative cohort of 7,500 mother-infant pairs. As such, a cohort that is diverse and representative of the US population must also include immigrants and those of those of Middle Eastern and North African (MENA) origins. There is currently no category on the US Census for those of MENA origins, as they are collapsed into the ‘White’ sample. Given that historically the US has prioritized refugee admissions from numerous MENA countries with a significant proportion being received in California, it is important to prepare for the expansion of MENA women who give birth in the US. Little is known with respect to MENA women’s behaviors and exposures during pregnancy, particularly with respect to substance use, or the pregnancy and birth outcomes of this population and how they compare to non-MENA populations. Future research of this small but growing population in the US will require researchers with expertise in maternal child health, underrepresented or marginalized populations, and cultural competency. The candidate for this Diversity Supplement has lived experience as a MENA refugee and is passionate about this work. Therefore, the overarching goals of this Diversity Supplement are to 1) explore MENA immigrant women’s maternal and infant health exposures, behaviors and outcomes, and 2) prepare Ms. Hamzai for a career studying the exposures and outcomes of MENA woman in birth cohorts. Ms. Hamzai will receive 1:1 training from PIs on the HBCD study with expertise in maternal-child health, marginalized populations, and perinatal substance use. She will participate and inform Working Groups pertaining to Diversity, Equity and Inclusion, Substance Use, Recruitment and Retention, and Perinatal Health. Importantly, she will have exposure to and networking opportunities with 25 successful site study teams around the US. Her research will synthesize the literature on exposures (e.g. substance use, displacement) among MENA populations, their engagement in research, and cultural considerations for exploring health-related topics (Aim 1), synthesizing the literature on MENA immigrant women’s maternal and birth outcomes (Aim 2), and analyzing available administrative cohort data of immigrant MENA mother-child pairs in California for both maternal and infant outcomes (Aim 3). This proposed training will bi-directionally benefit Ms. Hamzai and the HBCD study, as her research aims will inform the efforts of several working groups who are also focused on under-represented populations, and their expertise in design, recruitment and retention of under-represented populations will inform Ms. Hamzai’s research and career development.

这一多样性补充将嵌套在健康大脑和儿童发展国家联盟 在加州圣地亚哥大学（UCSD）研究中心进行的（六溴环十二烷-NC）研究（U 01 DA 055369，联系MPI：Bandoli）。 父母补助金的总体目标是制定一个大脑发育的规范模板，以应对 在生命的前十年里的各种暴露。为了实现这一目标，NIH选择了UCSD和其他25个地点 在美国（US）招募并随访了7，500名具有代表性的母亲-婴儿队列 对.因此，一个多样化并代表美国人口的群体也必须包括移民 以及中东和北非（MENA）起源的人。当前没有分类 美国人口普查为那些中东和北非地区的起源，因为他们是崩溃的“白色”样本。鉴于历史上 美国优先接纳来自许多中东和北非国家的难民，其中很大一部分是 在加州收到的，重要的是要准备扩大中东和北非妇女谁在美国分娩。小 关于MENA妇女在怀孕期间的行为和暴露，特别是关于 物质使用，或该人群的妊娠和分娩结果，以及与非中东和北非地区相比， 人口。未来对美国这个小但不断增长的人口的研究将需要具有专业知识的研究人员 在妇幼保健、代表性不足或被边缘化的人口以及文化能力方面。候选 作为中东和北非难民的生活经验，并对这项工作充满热情。 因此，这一多样性补充的总体目标是1）探索中东和北非移民妇女的 母婴健康暴露，行为和结果，2）为Hamzai女士的职业学习做好准备 出生队列中MENA妇女的暴露和结局。Hamzai女士将接受PI的1：1培训， 六溴环十二烷研究，具有母婴健康、边缘化人群和围产期药物使用方面的专门知识。 她将参加并告知有关多样性，公平和包容，物质使用， 招聘和保留，围产期健康。重要的是，她将接触和网络 我们与美国各地的25个成功的现场研究团队合作。她的研究将综合关于 中东和北非地区人口的暴露情况（如物质使用、流离失所），他们参与研究的情况，以及 探索健康相关主题的文化考虑（目标1），综合有关中东和北非移民的文献 妇女的孕产妇和出生结果（目标2），并分析现有的管理队列数据的移民 加州MENA母婴配对的母婴结局（目标3）。拟议的培训将 双向受益Hamzai女士和六溴环十二烷研究，因为她的研究目标将为几个国家的努力提供信息。 工作组也专注于代表性不足的人群，他们在设计方面的专业知识， 招聘和留住代表性不足的人口将为Hamzai女士的研究和职业生涯提供信息 发展