Outreach, Recruitment and Engagement Core

外展、招聘和参与核心

• 批准号: 10620680
• 负责人: Christine S Ritchie
• 金额: $ 21.13万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-15 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10620680
• 关键词: Affect; Agreement; Alzheimer' s Disease; Alzheimer' s disease related dementia; Area; Awareness; Biological Markers; Biology; Boston; Brain; Caring; Cities; Clinic; Clinical; Clinical Research; Clinical Trials; Collaborations; Communities; Community Health Education; Consultations; Cultural Diversity; Data; Databases; Dementia; Diagnosis; Diagnostic; Disease; Early Diagnosis; Education; Elderly; Electronic Mail; Enrollment; Environment; Ethnic Origin; Event; Evolution; Faculty; Faith; Fostering; Friends; Future; Genetic study; Goals; Health; Health Professional; Individual; Learning; Lewy Bodies; Massachusetts; Memory; Memory Disorders; Methods; Minority Groups; Mission; Natural History; Needs Assessment; Neurologist; Neurology; Neuropsychology; Participant; Prevention; Rapid diagnostics; Registries; Research; Resources; Risk; Sampling; Specialist; Teacher Professional Development; Therapeutic Trials; Training; Underrepresented Minority; Underrepresented Populations; Work; biobank; clinical center; cohort; community engagement; community organizations; community setting; dementia care; disease heterogeneity; diversity and inclusion; ethnic diversity; innovation; medical schools; minority communities; neuroimaging; outreach; participant enrollment; patient advocacy group; pharmacologic; programs; rapid technique; recruit; research study; skills; social media; socioeconomics; success; tool; volunteer; web site

Massachusetts Alzheimer’s Disease Research Center: Outreach, Recruitment and Engagement Core The Outreach, Recruitment and Engagement (ORE) Core of the Massachusetts Alzheimer’s Disease Research Center (MADRC) has shifted its focus towards early detection and prevention while concentrating on the critical need for diversity within clinical trials and research studies. This mission aligns well with MADRC’s overall goals for understanding disease heterogeneity; as diversity across education, ethnicity and socio- economic strata affects not only the biology of Alzheimer’s Disease (AD) and related dementias (ADRD) but the clinical expression of disease as well. Only as we expand and diversify participation in AD/ADRD clinical research will we acquire new strategies to find a cure. The ORE core will meet these challenges by focusing its mission in several areas: We will marshal resources to meet the recruitment and retention needs of the MADRC Clinical Core and all MADRC affiliated research studies (Aim 1). We will work with the Clinical Core to increase the clinical and demographic diversity of the Research Cohort in clinical and community settings. We will also develop liaisons with local and national groups to increase public awareness about AD/ADRD dementias, particularly within underrepresented minority groups (Aim 2) and work to increase diversity in all our research studies. We intend to collaborate with city and state agencies fostering a Dementia Friendly environment to bring education about prevention, AD/ADRD resources and clinical trial opportunities to underserved and ethnically diverse communities. We also intend to work with the Neuropath core to educate the public about the value of brain donation and the lessons learned from these studies (Aim 3). We intend to develop new strategies to facilitate rapid enrollment into clinical trials by working with the Data and Clinical cores to build and maintain a registry of research ready participants (Aim 4) who agree to be contacted as clinical and research trials become available. We will build toward the future by developing a Rapid Diagnostic Clinic to facilitate earlier diagnosis and enrollment of participants into research studies and working with the Data Core to recruit from a BioBank EHR Database that will allow rapid recruitment of large or highly customizable samples (Aim 5). We will also provide customized education and support to PCP practitioners, faith-based ministers and geriatric specialists who are on the frontlines of dementia care. We will work with the REC to train fellows in cultural diversity and community engagement (Aim 6). The ORE core interfaces with all the MADRC cores by providing education to the public about clinical, biomarker and genetic studies and the value of brain donations. It supports the recruitment needs of all the MADRC cores and affiliated research studies. Only together will we find a cure for AD/ADRD before 2025.

马萨诸塞州阿尔茨海默氏病研究中心：外展，招聘和参与核心 马萨诸塞州阿尔茨海默氏病的外展，招募和参与（矿石）核心 研究中心（MADRC）将注意力转向了早期发现和预防，同时专注于 临床试验和研究中对多样性的批判性需求。这项任务与马德克的 理解疾病异质性的总体目标；作为教育，种族和社会的多样性 - 经济层不仅影响阿尔茨海默氏病（AD）和相关痴呆症（ADRD）的生物学，而且还影响 疾病的临床表达也是如此。仅当我们扩展和多样化参与AD/ADRD临床 我们将获得新的策略来找到治疗方法。矿石核心将通过关注来应对这些挑战 它在多个领域的任务： 我们将元使用资源以满足Madrc临床核心的招聘和保留需求以及所有 MADRC会员研究研究（AIM 1）。我们将与临床核心合作以增加临床和 临床和社区环境中研究队列的人口多样性。我们还将发展联络 与地方和民族集团一起提高公众对AD/ADRD痴呆症的认识，尤其是在 代表性不足的少数群体（AIM 2），并在我们所有研究中努力增加多样性。我们打算 与城市和州机构合作，培养痴呆症友好环境以实现教育 预防，广告/ADRD资源和临床试验机会，为服务不足和种族差异 社区。我们还打算与Neuropath核心合作，以教育公众有关大脑的价值 捐赠和从这些研究中学到的教训（AIM 3）。 我们打算制定新的策略，以促进与数据合作的快速入学临床试验 和临床核心建立和维护研究参与者的注册表（AIM 4），他们同意成为 随着临床和研究试验的可用，已联系。 我们将通过开发一个快速诊断诊所来促进未来，以促进早期诊断和 参与者参与研究并与数据核心合作以从生物库EHR招募 可以快速募集大型或高度可定制样本的数据库（AIM 5）。我们还将提供 对PCP从业人员，基于信仰的部长和老年专家的定制教育和支持 在痴呆症护理的前线。我们将与Rec合作，以文化多样性培训研究员 社区参与（目标6）。 矿石核心与所有MADRC核心的界面通过向公众提供有关临床的教育， 生物标志物和遗传研究以及大脑捐赠的价值。它支持所有的招聘需求 MADRC核心和会员研究。只有在2025年之前，我们才能一起找到对AD/ADRD的治疗方法。