Palliative Care Research Cooperative Group (PCRC): Investigator Development Center

项目摘要/摘要 该U2C应用程序的主要目标是提高姑息治疗的工作效率和影响 研究合作小组(PCRC)，通过促进开展高质量、有效的临床 研究，并扩大姑息治疗研究人员的数量和专业知识，以进行多地点临床 审判。为了追求这些总体目标和目标，调查员发展中心(IDC)是两个 PCRC内的中心，努力为EOLPC研究中的调查人员配备必要的工具套件，以 为护理患有严重、晚期疾病的个人创造强有力的证据基础。的具体目标 IDC是：(1)增强各阶段研究人员成功开展多点临床的能力 通过：(A)通过以下方式支持研究、培训和开发： 体验式和说教式教学，(B)提供以姑息治疗原则为重点的结构化指导； EOLPC研究中经常遇到的方法学问题，以及转化性研究方法，(C) 管理PCRC试点项目方案，(D)提供临床试验培训和支持调查员 通过临床试验加强参与，以及(E)提供关于招募和 保留多样化和弱势群体；(2)为EOLPC开发、评估和提炼资源 各级研究人员根据当前的临床、伦理和法规进行临床试验 标准：(A)与其他PCRC核心合作，以加强咨询PCRC的研究的严谨性 并促进核心对调查员的一致和协调指导，(B)与调查员合作 来自不同的学科专业，并具有相关的专业知识，以发展开展 EOLPC的高质量、多地点临床研究，以及(C)与国内和国际合作 关于EOLPC研究培训和传播的组织；(3)通过(A)促进研究领导 通过量身定制的纵向导师培训提高辅导技能，(B)与项目合作 协调中心(PCC)，使PCRC成员能够担任有效的委员会成员和主席；以及 (C)培训调查人员计划研究、管理团队和执行项目；以及(4)建立研究 通过(A)扩大PCRC特殊兴趣小组和其他研究合作机会；以及 (B)定期评估和调整国际数据中心方案，以满足PCRC成员不断变化的需求。通过 为了实现这些目标，IDC将增加EOLPC工作人员的能力，以便有效地进行多项 实地考察。

PROJECT SUMMARY/ABSTRACT The primary goals of this U2C application are to increase the productivity and impact of the Palliative Care Research Cooperative Group (PCRC), through facilitating the conduct of high-quality, effective clinical research, and expanding the number and expertise of palliative care researchers to conduct multi-site clinical trials. In pursuit of these overall goals and objectives, the Investigator Development Center (IDC), one of two Centers within the PCRC, strives to equip investigators in EOLPC research with the suite of tools necessary to create a robust evidence base for the care of individuals with serious, advanced illness. The specific aims of the IDC are: (1) to enhance the capacity of investigators at all stages to successfully conduct multi-site clinical research in the area of EOLPC science by (a) supporting research training and development through experiential and didactic instruction, (b) providing structured mentoring focused on principles of palliative care, methodological issues commonly encountered in EOLPC research, and translational research approaches, (c) administering the PCRC Pilot Projects Program, (d) providing clinical trials training and sustaining investigator engagement through Clinical Trials Intensives, and (e) providing specific training on the recruitment and retention of diverse and vulnerable populations; (2) to develop, evaluate and refine resources for EOLPC investigators at all levels in the conduct of clinical trials according to current clinical, ethical and regulatory standards by (a) collaborating with other PCRC Cores to enhance rigor among studies that consult the PCRC and promote consistent and coordinated investigator guidance from the Cores, (b) partnering with investigators from diverse disciplinary specialties and with relevant expertise to develop competencies for the conduct of high-quality, multi-site clinical studies in EOLPC, and (c) collaborating with national and international organizations on EOLPC research training and dissemination; (3) to promote research leadership by (a) enhancing mentoring skills through tailored, longitudinal mentor training, (b) partnering with the Project Coordinating Center (PCC) to equip PCRC members to serve as effective committee members and chairs, and (c) training investigators to plan research, manage teams, and execute projects; and (4) to build a research community by (a) expanding PCRC special interest groups and other research collaboration opportunities, and (b) regularly evaluating and tailoring IDC programs to meet the evolving needs of PCRC constituents. By achieving these aims, the IDC will increase the capacity of the EOLPC workforce to effectively conduct multi- site studies.