PESC Core

项目概要：初步和探索性研究核心（PESC） 试点和探索性研究核心（PESC）的总体目标是促进创新和有前途的 研究老年残疾的预测因素、结果和改善情况，特别是弱势群体 人口数量。这一更新申请建立在UCSF PESC在过去4年的成功， 确定有前途的飞行员，导致11个R01或同等奖项，7个其他R系列奖项，7个K级奖项， 1项NIH新创新者奖，31项非NIH资金来源的赠款。PESC将促进创新 和有前途的研究，通过以下具体目标将试点资金用于未来的赠款： 1.通过征集和选择具有创新意义的 来自高素质申请人的建议。 2.为PESC研究的研究者提供研究设计、分析、招募和保留 通过使用OAIC核心，特别是数据和分析核心， (DAC)脆弱老龄化招募和保留核心（VARC）。 3.将PESC研究和研究人员与UCSF临床和转化资源整合 科学研究所（CTSI），多样化社区老龄化中心，弱势群体中心， 和其他相关资源。 4.通过定期OAIC与PESC获奖者的接触，促进PESC研究的成功， 加强跟踪试点研究的进展和影响。 5.通过参与OAIC范围内的多样性，促进老龄问题研究人员的多样性 该计划为申请PESC资金的不同背景的候选人提供具体支持。 通过PESC，进行衰老研究的有前途的研究人员将有一种机制， 初步数据，以建立与OAIC主题有关的未来独立资助的研究项目。

Project Summary: Pilot and Exploratory Studies Core (PESC) The overall goal of the Pilot and Exploratory Studies Core (PESC) is to promote innovative and promising research addressing the predictors, outcomes and amelioration of late-life disability, especially in vulnerable populations. This renewal application builds on the success of the UCSF PESC over the past 4 years in identifying promising pilots that led to 11 R01 or equivalent awards, 7 other R-series awards, 7 K-level awards, 1 NIH New Innovator award, and 31 grants from non-NIH funding sources. The PESC will promote innovative and promising research by leveraging pilot funding into future grants through the following specific aims: 1. Identify and foster champions in aging research through the solicitation and selection of innovative proposals from highly qualified applicants. 2. Provide investigators of PESC studies support in study design, analysis, recruitment and retention of diverse and vulnerable populations through use of the OAIC Cores, specifically the Data and Analysis Core (DAC) and the Vulnerable Aging Recruitment and Retention Core (VARC). 3. Integrate PESC studies and investigators with resources from the UCSF Clinical and Translational Science Institute (CTSI), the Center for Aging in Diverse Communities, the Center for Vulnerable Populations, and other relevant resources at UCSF. 4. Foster the success of PESC studies through regular OAIC engagement with PESC awardees and augmented tracking of pilot studies’ progress and impact. 5. Promote diversity among researchers in aging, through participation in the OAIC-wide Diversity Program that offers specific support for candidates from diverse backgrounds who apply for PESC funding. Through the PESC, promising investigators conducting aging research will have a mechanism to obtain crucial preliminary data upon which to build future independently-funded research projects relating to the OAIC theme.