The Mindful and Self-Compassionate Care Program (MASC): Reducing Stress for Caregivers of Persons with Dementia

正念和自我关怀护理计划 (MASC)：减轻痴呆症患者护理人员的压力

• 批准号: 10505172
• 负责人: Christine S Ritchie
• 金额: $ 45.46万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10505172
• 关键词: Adherence; Adult; Aggressive behavior; Agitation; Alzheimer' s Disease; Alzheimer' s disease related dementia; Anxiety; Behavior; Behavioral; Behavioral Sciences; Benchmarking; Bypass; Caregivers; Caring; Clinical Trials; Compassion; Complex; Data; Dementia; Dementia caregivers; Dissemination and Implementation; Distress; Effectiveness; Empathy; Enrollment; Ensure; Feasibility Studies; Focus Groups; Fostering; Funding; Geography; Goals; Guilt; Health; Health education; Home; Hybrids; Individual; Intervention; Interview; Language; Lead; Loneliness; Massachusetts; Meditation; Mental Depression; Modality; Modeling; Morbidity - disease rate; Outcome; Patient Self-Report; Patients; Perception; Personal Satisfaction; Persons; Positioning Attribute; Procedures; Public Health; Randomized; Regimen; Reporting; Research; Risk; Sampling; Science; Self Efficacy; Services; Signal Transduction; Single-Blind Study; Social support; Stress; Structure; Support Groups; Time; United States National Institutes of Health; Well in self; Work; base; behavior change; care giving burden; care recipients; caregiver stress; clinically relevant; collaborative care; community center; dementia care; depressive symptoms; design; effectiveness trial; emotion regulation; emotional distress; ethnic minority; evidence base; experience; feasibility testing; follow-up; improved; loved ones; mindfulness; mortality; physical conditioning; programs; psychologic; racial minority; recruit; secondary outcome; skills; stress management; therapy development; uptake; video delivery; virtual; virtual delivery; web platform

PROJECT SUMMARY: Within a 3-year R01 we will use the NIH stage model and principles from the Science of Behavioral Change to develop, optimize and establish proof of concept for the Mindful, Self-Compassionate Care Program (MASC) for stressed caregivers of persons with ADRD with challenging behaviors. In aim 1, we will use qualitative focus groups to develop MASC (NIH stage 1A; up to 30 caregivers; n=4 groups). In aim 2, we will optimize MASC and conduct an open pilot with exit interviews to explore feasibility benchmarks, target engagement and signal of improvement in stress, depression, anxiety and well- being (NIH stage 1A; up to 10 caregivers; n=1 group). In aim 3, we will conduct a pilot RCT of MASC versus a Health Education control to establish feasibility benchmarks and preliminary efficacy and explore evidence for potential mechanisms of improvement through the proposed mechanistic targets (N=80/c0 completers). MASC combines evidence- based skills from mindfulness programs, self-compassion programs, and behavioral management programs. MASC structure and components are designed to facilitate uptake, skill practice, and sustainability of improvements. MASC has 6 sessions and is delivered virtually in groups. MASC has an associated web platform that facilitates skills practice and is available to caregivers after the group ends. Our guiding hypothesis is that MASC skills of mindfulness, self-compassion, and behavioral management will interact and lead to decreased stress, depression and anxiety and improved well-being, through decreased loneliness, increased caregiver self-efficacy, social support, mindfulness, self-compassion, compassion and improved relationship quality. Our team is well positioned to conduct this study with specific experience in mindfulness and self-compassion programs; intervention development, feasibility testing and clinical trials; ADRD caregivers; recruitment of national, geographically diverse samples. At the end of the 3-year period of this R01 we will have clear evidence of the feasibility of study procedures, randomization, acceptability, credibility, adherence, ability to retain and recruit as well as its proof of concepts in reducing stress in caregivers of people with ADRD and proposed mechanisms. Results from this R01 study will be used to apply for funding to conduct a fully powered hybrid efficacy-effectiveness RCT. The goal is dissemination and implementation of MASC to reduce stress, among all in need caregivers of persons with ADRD.

项目概要： 在3年的R 01中，我们将使用NIH阶段模型和行为改变科学的原则来开发， 优化并建立针对压力较大的护理人员的正念、自我同情护理计划（MASC）的概念验证 具有挑战性行为的ADRD患者。在目标1中，我们将使用定性焦点小组来开发MASC（NIH 1A期;最多30名护理人员; n=4组）。在目标2中，我们将优化MASC，并进行一项带有离职面谈的公开试点 探索可行性基准，目标参与度和压力，抑郁，焦虑和健康改善的信号， （NIH 1A期;最多10名护理人员; n=1组）。在目标3中，我们将进行一项MASC与健康 教育控制，以建立可行性基准和初步功效，并探索潜在的证据 通过提出的机制目标的改善机制（N=80/c 0完成者）。MASC结合证据- 基于正念项目、自我同情项目和行为管理项目的技能。MASC 结构和组成部分的设计，以促进吸收，技能的做法，和改进的可持续性。MASC有6个 会议，并以小组形式提供。MASC有一个相关的网络平台，促进技能实践， 在小组结束后提供给照顾者。我们的指导假设是，MASC的正念，自我同情， 和行为管理将相互作用，并导致减少压力，抑郁和焦虑，改善福祉， 通过减少孤独，增加照顾者自我效能，社会支持，正念，自我同情，同情 改善关系质量。我们的团队在正念方面有着丰富的经验， 和自我同情计划;干预开发，可行性测试和临床试验; ADRD护理人员; 招募来自不同国家、不同地域的样本。在本R 01的3年期结束时，我们将明确 研究程序的可行性、随机化、可接受性、可信度、依从性、保留能力和 招募以及它的概念证明在减少与ADRD和拟议的机制的人的照顾者的压力。 本R 01研究的结果将用于申请资金，以开展一项具有充分把握度的混合疗效-有效性RCT。 目标是传播和实施多学科支助方案，以减轻所有需要照顾残疾人的人的压力。 ADRD。