The Mindful and Self-Compassionate Care Program (MASC): Reducing Stress for Caregivers of Persons with Dementia

正念和自我关怀护理计划 (MASC)：减轻痴呆症患者护理人员的压力

• 批准号: 10505172
• 负责人: Christine S Ritchie
• 金额: $ 45.46万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10505172
• 关键词: Adherence; Adult; Aggressive behavior; Agitation; Alzheimer' s Disease; Alzheimer' s disease related dementia; Anxiety; Behavior; Behavioral; Behavioral Sciences; Benchmarking; Bypass; Caregivers; Caring; Clinical Trials; Compassion; Complex; Data; Dementia; Dementia caregivers; Dissemination and Implementation; Distress; Effectiveness; Empathy; Enrollment; Ensure; Feasibility Studies; Focus Groups; Fostering; Funding; Geography; Goals; Guilt; Health; Health education; Home; Hybrids; Individual; Intervention; Interview; Language; Lead; Loneliness; Massachusetts; Meditation; Mental Depression; Modality; Modeling; Morbidity - disease rate; Outcome; Patient Self-Report; Patients; Perception; Personal Satisfaction; Persons; Positioning Attribute; Procedures; Public Health; Randomized; Regimen; Reporting; Research; Risk; Sampling; Science; Self Efficacy; Services; Signal Transduction; Single-Blind Study; Social support; Stress; Structure; Support Groups; Time; United States National Institutes of Health; Well in self; Work; base; behavior change; care giving burden; care recipients; caregiver stress; clinically relevant; collaborative care; community center; dementia care; depressive symptoms; design; effectiveness trial; emotion regulation; emotional distress; ethnic minority; evidence base; experience; feasibility testing; follow-up; improved; loved ones; mindfulness; mortality; physical conditioning; programs; psychologic; racial minority; recruit; secondary outcome; skills; stress management; therapy development; uptake; video delivery; virtual; virtual delivery; web platform

PROJECT SUMMARY: Within a 3-year R01 we will use the NIH stage model and principles from the Science of Behavioral Change to develop, optimize and establish proof of concept for the Mindful, Self-Compassionate Care Program (MASC) for stressed caregivers of persons with ADRD with challenging behaviors. In aim 1, we will use qualitative focus groups to develop MASC (NIH stage 1A; up to 30 caregivers; n=4 groups). In aim 2, we will optimize MASC and conduct an open pilot with exit interviews to explore feasibility benchmarks, target engagement and signal of improvement in stress, depression, anxiety and well- being (NIH stage 1A; up to 10 caregivers; n=1 group). In aim 3, we will conduct a pilot RCT of MASC versus a Health Education control to establish feasibility benchmarks and preliminary efficacy and explore evidence for potential mechanisms of improvement through the proposed mechanistic targets (N=80/c0 completers). MASC combines evidence- based skills from mindfulness programs, self-compassion programs, and behavioral management programs. MASC structure and components are designed to facilitate uptake, skill practice, and sustainability of improvements. MASC has 6 sessions and is delivered virtually in groups. MASC has an associated web platform that facilitates skills practice and is available to caregivers after the group ends. Our guiding hypothesis is that MASC skills of mindfulness, self-compassion, and behavioral management will interact and lead to decreased stress, depression and anxiety and improved well-being, through decreased loneliness, increased caregiver self-efficacy, social support, mindfulness, self-compassion, compassion and improved relationship quality. Our team is well positioned to conduct this study with specific experience in mindfulness and self-compassion programs; intervention development, feasibility testing and clinical trials; ADRD caregivers; recruitment of national, geographically diverse samples. At the end of the 3-year period of this R01 we will have clear evidence of the feasibility of study procedures, randomization, acceptability, credibility, adherence, ability to retain and recruit as well as its proof of concepts in reducing stress in caregivers of people with ADRD and proposed mechanisms. Results from this R01 study will be used to apply for funding to conduct a fully powered hybrid efficacy-effectiveness RCT. The goal is dissemination and implementation of MASC to reduce stress, among all in need caregivers of persons with ADRD.

项目摘要： 在3年的R01中，我们将使用NIH阶段模型和行为改变科学的原则来发展， 为紧张的护理人员优化并建立正念，自招的护理计划（MASC）的概念验证 具有充满挑战行为的ADRD的人。在AIM 1中，我们将使用定性焦点小组开发MASC（NIH 第1A阶段；多达30名照料者； n = 4组）。在AIM 2中，我们将优化MASC并进行开放式飞行员，并进行退出访谈 探索可行性基准，目标参与度以及压力，抑郁，焦虑和良好的改善信号 存在（NIH 1A阶段；最多10名护理人员； n = 1组）。在AIM 3中，我们将进行MASC与健康的飞行员RCT 教育控制以建立可行性基准和初步疗效，并探讨潜在的证据 通过提出的机械目标改进的机制（n = 80/c0完成者）。 MASC结合了证据 - 正念计划，自我同情计划和行为管理计划的基于技能。 Masc 结构和组件旨在促进采用，技能实践和改进的可持续性。 MASC有6个 会议，几乎分组交付。 MASC拥有一个相关的网络平台，可促进技能实践，并且是 小组结束后，护理人员可以使用。我们的指导假设是正念，自我同情的MASC技能 行为管理将相互作用，并导致压力减轻，抑郁和焦虑以及改善的幸福感， 通过减少孤独感，增加照顾者的自我效能感，社会支持，正念，自我同情，同情心 并改善了关系质量。我们的团队在正念方面具有特定经验的精神，可以进行这项研究 和自我同情计划；干预开发，可行性测试和临床试验； ADRD护理人员； 招募国家地理不同样本。在此R01的3年结束时，我们将有清晰的 研究程序，随机化，可接受性，信誉，依从性，保留能力和 招募及其在减少ADRD和拟议机制的人的护理人员压力方面的概念证明。 这项R01研究的结果将用于申请资金以进行全功率的混合功效效果RCT。 目的是传播和实施MASC以减轻压力 adrd。