The Mindful and Self-Compassionate Care Program (MASC): Reducing Stress for Caregivers of Persons with Dementia

项目总结： 在为期3年的R01中，我们将使用NIH阶段模型和行为改变科学的原理来开发， 为有压力的照顾者优化和建立正念、自我同情护理计划(MASC)的概念证明 有挑战性行为的ADRD患者。在目标1中，我们将使用定性焦点小组来开发MASC(NIH 阶段1A；最多30名照顾者；n=4组)。在目标2中，我们将优化MASC并进行公开试点和离职访谈 探索可行性基准、目标参与度和压力、抑郁、焦虑和健康状况改善的信号 Being(NIH阶段1A；最多10名照顾者；n=1组)。在目标3中，我们将进行MASC与A Health的RCT试点 教育控制，以建立可行性基准和初步效果，并探索潜在证据 通过拟议的机械性目标改进的机制(N=80/c0完成者)。MASC综合了证据- 基于正念计划、自我同情计划和行为管理计划的技能。MASC 结构和组件旨在促进理解、技能练习和改进的可持续性。MASC有6个 课程，并以小组形式进行虚拟授课。MASC有一个相关的Web平台，可促进技能练习，并 在小组结束后，照顾者可以使用。我们的指导性假设是MASC技能的正念，自我同情， 行为管理将相互作用，导致压力、抑郁和焦虑的减少，并改善幸福感， 通过减少孤独感，增加照顾者的自我效能感，社会支持，正念，自我同情，同情 和改善的关系质量。我们的团队有很好的条件进行这项研究，在正念方面有特殊的经验。 和自我同情计划；干预开发、可行性测试和临床试验；ADRD照顾者； 招募不同国家、不同地域的样本。在本R01的3年期结束时，我们将有明确的 研究程序的可行性证据、随机化、可接受性、可信度、依从性、保留和 Recruit及其在减轻ADRD患者照顾者压力方面的概念证明以及拟议的机制。 这项R01研究的结果将被用于申请资金，以进行完全动力的混合功效-有效性随机对照试验。 目标是在所有有需要的照顾者中传播和实施MASC，以减轻压力 阿德勒。

PROJECT SUMMARY: Within a 3-year R01 we will use the NIH stage model and principles from the Science of Behavioral Change to develop, optimize and establish proof of concept for the Mindful, Self-Compassionate Care Program (MASC) for stressed caregivers of persons with ADRD with challenging behaviors. In aim 1, we will use qualitative focus groups to develop MASC (NIH stage 1A; up to 30 caregivers; n=4 groups). In aim 2, we will optimize MASC and conduct an open pilot with exit interviews to explore feasibility benchmarks, target engagement and signal of improvement in stress, depression, anxiety and well- being (NIH stage 1A; up to 10 caregivers; n=1 group). In aim 3, we will conduct a pilot RCT of MASC versus a Health Education control to establish feasibility benchmarks and preliminary efficacy and explore evidence for potential mechanisms of improvement through the proposed mechanistic targets (N=80/c0 completers). MASC combines evidence- based skills from mindfulness programs, self-compassion programs, and behavioral management programs. MASC structure and components are designed to facilitate uptake, skill practice, and sustainability of improvements. MASC has 6 sessions and is delivered virtually in groups. MASC has an associated web platform that facilitates skills practice and is available to caregivers after the group ends. Our guiding hypothesis is that MASC skills of mindfulness, self-compassion, and behavioral management will interact and lead to decreased stress, depression and anxiety and improved well-being, through decreased loneliness, increased caregiver self-efficacy, social support, mindfulness, self-compassion, compassion and improved relationship quality. Our team is well positioned to conduct this study with specific experience in mindfulness and self-compassion programs; intervention development, feasibility testing and clinical trials; ADRD caregivers; recruitment of national, geographically diverse samples. At the end of the 3-year period of this R01 we will have clear evidence of the feasibility of study procedures, randomization, acceptability, credibility, adherence, ability to retain and recruit as well as its proof of concepts in reducing stress in caregivers of people with ADRD and proposed mechanisms. Results from this R01 study will be used to apply for funding to conduct a fully powered hybrid efficacy-effectiveness RCT. The goal is dissemination and implementation of MASC to reduce stress, among all in need caregivers of persons with ADRD.