PESC Core

项目摘要：试点和探索性研究核心(PESC) 先导和探索性研究核心(PESC)的总体目标是促进创新和有前途的 关于晚年残疾的预测因素、结果和改善的研究，特别是在弱势群体中 人口。此续约申请建立在加州大学旧金山分校PESC在过去4年中 确定有前途的飞行员，获得11个R01或同等奖项，7个其他R系列奖项，7个K级奖项， 1个NIH新创新者奖，31个来自非NIH资金来源的赠款。PESC将推动创新 并通过以下具体目标将试点资金用于未来的赠款，从而进行有前景的研究： 1.通过征集和遴选创新人才，发现和培育老龄化研究的领军者 来自高素质申请者的建议书。 2.为PESC研究人员提供研究设计、分析、招聘和保留方面的支持 通过使用OAIC核心，特别是数据和分析核心，实现多样化和弱势群体 (发援会)和脆弱老龄化招募和保留核心(VARC)。 3.将PESC研究和研究人员与加州大学旧金山分校临床和翻译中心的资源整合 科学研究所(CTSI)、不同社区老龄中心、弱势群体中心、 以及加州大学旧金山分校的其他相关资源。 4.通过与PESC获奖者的定期接触，促进PESC研究的成功 加强了对试点研究进展和影响的跟踪。 5.通过参与OAIC范围的多样性，促进老龄问题研究人员的多样性 为申请PESC资金的不同背景的候选人提供具体支持的计划。 通过PESC，有前途的研究人员进行衰老研究将有一个机制，以获得关键的 初步数据，以此为基础建立未来独立资助的与伊斯兰会议组织主题有关的研究项目。

Project Summary: Pilot and Exploratory Studies Core (PESC) The overall goal of the Pilot and Exploratory Studies Core (PESC) is to promote innovative and promising research addressing the predictors, outcomes and amelioration of late-life disability, especially in vulnerable populations. This renewal application builds on the success of the UCSF PESC over the past 4 years in identifying promising pilots that led to 11 R01 or equivalent awards, 7 other R-series awards, 7 K-level awards, 1 NIH New Innovator award, and 31 grants from non-NIH funding sources. The PESC will promote innovative and promising research by leveraging pilot funding into future grants through the following specific aims: 1. Identify and foster champions in aging research through the solicitation and selection of innovative proposals from highly qualified applicants. 2. Provide investigators of PESC studies support in study design, analysis, recruitment and retention of diverse and vulnerable populations through use of the OAIC Cores, specifically the Data and Analysis Core (DAC) and the Vulnerable Aging Recruitment and Retention Core (VARC). 3. Integrate PESC studies and investigators with resources from the UCSF Clinical and Translational Science Institute (CTSI), the Center for Aging in Diverse Communities, the Center for Vulnerable Populations, and other relevant resources at UCSF. 4. Foster the success of PESC studies through regular OAIC engagement with PESC awardees and augmented tracking of pilot studies’ progress and impact. 5. Promote diversity among researchers in aging, through participation in the OAIC-wide Diversity Program that offers specific support for candidates from diverse backgrounds who apply for PESC funding. Through the PESC, promising investigators conducting aging research will have a mechanism to obtain crucial preliminary data upon which to build future independently-funded research projects relating to the OAIC theme.