Tri-Institutional PhD Program in Chemical Biology
化学生物学三机构博士项目
基本信息
- 批准号:10618939
- 负责人:
- 金额:$ 31.83万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-07-01 至 2025-06-30
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
PROJECT SUMMARY
Tri-Institutional PhD Program in Chemical Biology (TPCB)
The Tri-Institutional PhD Program in Chemical Biology (TPCB) is an innovative graduate program that
provides students with comprehensive training at the interface of chemistry, biology, and medicine. TPCB is
unique in that it is offered jointly by three premier research institutions with adjacent campuses in the heart of
New York City: Memorial Sloan Kettering Cancer Center, The Rockefeller University, and Weill Cornell
Medical College. This stand-alone, direct admission graduate program was established in 2001 as one of the
first in the nation to focus specifically on training the next generation of chemical biology researchers.
Over the last 19 years, TPCB has established itself as a leading graduate program in chemical biology, with 70
PhD graduates and 43 current students (26 training grant-eligible, TGE). Students come from both chemical
and biological backgrounds and the program combines quantitative chemical training with deep insights into
forefront problems in biomedical research. Students also come from a wide range of scientific and cultural
backgrounds and this diversity is celebrated. The program welcomes students from underrepresented minority
groups, those with disabilities, and those from disadvantaged socioeconomic backgrounds (currently totaling
35% of TGE) and works with each student individually to ensure they have the resources necessary to thrive.
The curriculum includes two chemical biology courses created specifically for TPCB students, additional core
and elective courses, a seminar course, lab rotations, student Research-in-Progress seminars, annual student-
organized Tri-I Chemical Biology Symposium and TPCB Student Career Development Retreat, and the
Sanders Tri-I Chemical Biology Seminar Series. Students receive extensive career development training and
formal ongoing instruction in Responsible Conduct of Research and Rigor & Reproducibility. Students have
opportunities to conduct PhD thesis research with 54 dedicated faculty mentors working across the spectrum of
chemical biology with >$1M average annual funding. Students move seamlessly between the three institutions
and have access to the state-of-the-art research facilities and rich scientific environment on all three
campuses, providing diverse opportunities to pursue fundamental and translational research and to engage in
multidisciplinary collaborations. Importantly, TPCB students are deeply involved in the organization and design
of the training experience, and the program has evolved continually in response to student feedback.
As a result, TPCB students have been exceptionally productive, publishing over 400 scientific papers (average
5.2 papers/graduate), graduating in an average of 5.5 years. TPCB alumni have continued onto a wide range
of successful careers across the tenure track (17%), pharma (12%), biotech (29%), other labs (10%), and
research-related careers (31%). TPCB receives strong institutional support but is still unable to admit all of the
qualified candidates who apply. Thus, this NIGMS Chemistry–Biology Interface T32 training grant will enable
further growth and enhancement of this successful training program and its broader impacts on the community.
项目总结
项目成果
期刊论文数量(15)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins.
- DOI:10.1016/j.jbc.2023.104664
- 发表时间:2023-05
- 期刊:
- 影响因子:4.8
- 作者:Kotliar, Ilana B.;Ceraudo, Emilie;Kemelmakher-Liben, Kevin;Oren, Deena A.;Lorenzen, Emily;Dodig-Crnkovic, Tea;Horioka-Duplix, Mizuho;Huber, Thomas;Schwenk, Jochen M.;Sakmar, Thomas P.
- 通讯作者:Sakmar, Thomas P.
Students' Perspective on Scientific Training.
学生对科学训练的看法。
- DOI:10.1002/cbic.202300054
- 发表时间:2023
- 期刊:
- 影响因子:0
- 作者:Chua,GabriellaNL;Vandana,JJeya;Hsieh,Chun-Cheng
- 通讯作者:Hsieh,Chun-Cheng
Genetic code expansion to enable site-specific bioorthogonal labeling of functional G protein-coupled receptors in live cells.
- DOI:10.1002/pro.4550
- 发表时间:2023-02
- 期刊:
- 影响因子:8
- 作者:Mattheisen, Jordan M.;Wollowitz, Jaina S.;Huber, Thomas;Sakmar, Thomas P.
- 通讯作者:Sakmar, Thomas P.
Elucidating the Interactome of G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins.
- DOI:10.1124/pharmrev.120.000180
- 发表时间:2023-01
- 期刊:
- 影响因子:21.1
- 作者:
- 通讯作者:
Detection of SARS-CoV-2 RNA Using a DNA Aptamer Mimic of Green Fluorescent Protein.
- DOI:10.1021/acschembio.1c00893
- 发表时间:2022-04-15
- 期刊:
- 影响因子:4
- 作者:VarnBuhler, Bria S.;Moon, Jared;Dey, Sourav Kumar;Wu, Jiahui;Jaffrey, Samie R.
- 通讯作者:Jaffrey, Samie R.
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{{ truncateString('DEREK S TAN', 18)}}的其他基金
Tri-Institutional PhD Program in Chemical Biology
化学生物学三机构博士项目
- 批准号:
10414800 - 财政年份:2020
- 资助金额:
$ 31.83万 - 项目类别:
Predictive Models for Small-Molecule Accumulation in Gram-Negative Bacteria
革兰氏阴性细菌中小分子积累的预测模型
- 批准号:
10226047 - 财政年份:2018
- 资助金额:
$ 31.83万 - 项目类别:
Predictive Models for Small-Molecule Accumulation in Gram-Negative Bacteria
革兰氏阴性细菌中小分子积累的预测模型
- 批准号:
10460988 - 财政年份:2018
- 资助金额:
$ 31.83万 - 项目类别:
Predictive Models for Small-Molecule Accumulation in Gram-Negative Bacteria
革兰氏阴性细菌中小分子积累的预测模型
- 批准号:
9761970 - 财政年份:2018
- 资助金额:
$ 31.83万 - 项目类别:
Predictive Models for Small-Molecule Accumulation in Gram-Negative Bacteria
革兰氏阴性细菌中小分子积累的预测模型
- 批准号:
9982190 - 财政年份:2018
- 资助金额:
$ 31.83万 - 项目类别:
Tri-Institutional PhD Program in Chemical Biology
化学生物学三机构博士项目
- 批准号:
9306134 - 财政年份:2015
- 资助金额:
$ 31.83万 - 项目类别:
Tri-Institutional PhD Program in Chemical Biology
化学生物学三机构博士项目
- 批准号:
8935325 - 财政年份:2015
- 资助金额:
$ 31.83万 - 项目类别:
Tri-Institutional PhD Program in Chemical Biology
化学生物学三机构博士项目
- 批准号:
9098769 - 财政年份:2015
- 资助金额:
$ 31.83万 - 项目类别:
Rational Design of Adenylation Enzyme Inhibitors
腺苷酸化酶抑制剂的合理设计
- 批准号:
8675862 - 财政年份:2012
- 资助金额:
$ 31.83万 - 项目类别:
Small Molecule Inhibitors of P. aeruginosa Quinolone (Pqs) Quorum Sensing
铜绿假单胞菌喹诺酮 (Pqs) 群体感应的小分子抑制剂
- 批准号:
8268842 - 财政年份:2012
- 资助金额:
$ 31.83万 - 项目类别:
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