UNC Developmental Disabilities Research Center

描述（由申请人提供）：北卡罗来纳州精神发育迟滞和发育障碍研究中心（DDRC）的大学是一个跨学科的计划与使命，以支持和促进相关的研究，了解神经发育障碍的发病机制和治疗/预防。 该中心是研究和研究培训有关的智力迟钝和发育障碍的中心。 该中心目前支持来自21个大学部门的63名研究人员，包括135个外部资助的研究项目（102个PHS），涵盖MRDD研究中心RFA中列出的所有31个内容领域。 这个基础广泛的研究计划是很好地围绕一个投资组合的生物行为研究项目的神经发育障碍突出的几个NIH资助的跨学科研究中心自闭症（ACE网络; STAART中心），脆性X综合征（NICHD中心计划）和精神分裂症（康特中心）的资金。 生物行为研究服务于整合与MRDD相关的基础生物学和行为研究中的优秀研究项目。 39名中心研究人员积极参与73个资助项目，研究16种神经发育综合征。 在过去的八年里，DDRC的成功导致了最近在佛罗里达州建立了一个新的2000万美元的研究，教育和治疗发育性残疾的研究所，卡罗莱纳发育性残疾研究所。 该申请寻求对一个行政核心和四个研究核心的支持-数据管理和统计分析核心，主题注册核心，行为测量核心和发育神经影像核心。 这四个研究核心为MRDD研究的综合多学科计划提供了尖端，高质量和成本效益的支持。 对该中心的支持对北卡罗来纳州大学的发育残疾研究和研究培训产生了重大影响。 继续支持这一P30研究中心是一个必不可少的元素，为新的卡罗莱纳研究所在马萨诸塞州的计划。

DESCRIPTION (provided by applicant): The University of North Carolina Mental Retardation and Developmental Disabilities Research Center (DDRC) is an interdisciplinary program with a mission to support and promote research relevant to understanding the pathogenesis and treatment/prevention of neurodevelopmental disorders. The UNC DDRC is the focal point for research and research training relevant to mental retardation and developmental disabilities on the UNC campus. This Center currently supports 63 investigators from 21 University departments, and includes 135 externally-funded research projects (102 PHS) covering all 31 content areas listed in the RFA for MRDD Research Centers. This broad-based research program is well integrated around a portfolio of bio-behavioral research projects on neurodevelopmental disorders highlighted by the funding of several NIH-funded, interdisciplinary research centers on autism (ACE Network; STAART Center), fragile X syndrome (NICHD Centers Program) and schizophrenia (Conte Center). Bio-behavioral studies serve to integrate outstanding research programs in basic biological and behavioral research relevant to MRDD. Thirty-nine Center investigators are actively involved in 73 funded projects studying 16 neurodevelopmental syndromes. The success of this DDRC, over the last eight years, has resulted in the recent establishment of a new $20 million institute at UNC for research, education, and treatment of developmental disabilities, the Carolina Institute for Developmental Disabilities. This application seeks support for an Administrative Core and four research cores - the Data Management and Statistical Analysis Core, the Subject Registry Core, the Behavioral Measurement Core; and the Developmental Neuroimaging Core. These four research cores provide cutting-edge, high-quality, and cost effective support for this integrated, multidisciplinary program of MRDD research. Support for this Center has had a major impact on developmental disabilities research and research training at the University of North Carolina. Continued support of this P30 research center is an essential element of the plans for the new Carolina Institute at UNC.