12th Annual Midwest DNA Repair Symposium

第十二届年度中西部 DNA 修复研讨会

• 批准号: 7916026
• 负责人: J CHRISTOPHER STATES
• 金额: $ 0.8万
• 依托单位: UNIVERSITY OF LOUISVILLE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7916026
• 关键词: Age; Cardiovascular Diseases; Cardiovascular system; Cell physiology; Chronic; Chronic Disease; Collaborations; DNA Damage; DNA Repair; Development; Disease; Extramural Activities; Fostering; Functional disorder; Funding; Genome; Goals; Health; Home environment; Human; Inherited; Institution; Link; Maintenance; Malignant Neoplasms; Michigan; Mutagenesis; Nerve Degeneration; Neurodegenerative Disorders; Oral; Postdoctoral Fellow; Prevention; Recycling; Research; Research Personnel; Scientist; Secure; Series; Students; Time; Universities; Work; base; cost; environmental agent; graduate student; human disease; meetings; peer; posters; public health relevance; success; symposium

DESCRIPTION (provided by applicant): The 12th Annual Midwest DNA Repair Symposium (AMDRS) will take place in Louisville, KY on May 15 - 16, 2010 at the Shelby Campus of the University of Louisville. The AMDRS started in 1999 at the University of Michigan - Ann Arbor and has met at various universities in the Midwest every year since then. The Midwest DNA Repair Symposium was originally conceived as a forum to bring together DNA repair researchers from the Midwestern region on an annual basis to discuss ongoing research and to stimulate collaborations. Additional goals of the AMDRS include making the cost of attending the symposium as inexpensive as possible and to provide young investigators, postdoctoral fellows and graduate students priority in presenting their work in oral and poster sessions. DNA repair is a fundamental cellular process critical to maintenance of genome integrity and human health. DNA repair dysfunction has been linked with many inherited diseases as well as chronic diseases such as neurodegeneration, cardiovascular disease, aging and cancer. The investigators are pleased that this symposia series has been very successful and has seen significant increase in attendance the past several years. One key to the success has been to keep the costs of attendance low. This low cost has been possible because the organizers for each year held the symposium at their home institutions and have secured both intramural and extramural funding to cover some of the major expenses. Especially in times of restricted funding, the AMDRS is one meeting to which PI's have been able to bring their students and post-doctoral fellows to interact with leading scientists in the field and to present their work among peers. The AMDRS is now in its second decade and has started to recycle. In 2010, the AMDRS is returning to Louisville. The three principle goals of the AMDRS: 1) to provide a venue for scientists mainly from the Midwestern states, to present and discuss current research in the field of DNA damage, repair and mutagenesis, and to provide opportunities to foster scientific collaborations. (2) To provide students, postdoctoral fellows, and beginning independent investigators the opportunity to p resent their work to peers and to interact with leaders in the field. (3) To provide an exceptional value of these symposia by keeping them affordable. PUBLIC HEALTH RELEVANCE: Environmental agents that cause DNA damage contribute to the development and progression of chronic human disease including cancer, and cardiovascular and neurodegenerative diseases. DNA repair is an essential cellular processes that removes the DNA damage and efficient DNA repair is essential to prevention of these chronic diseases. This symposium will bring together DNA repair researchers to discuss their newest research, to exchange ideas and to develop new collaborations.

描述（由申请人提供）：第12届年度中西部DNA修复研讨会（AMDRS）将于2010年5月15日至16日在路易斯维尔，肯塔基州的路易斯维尔大学谢尔比校区举行。AMDRS于1999年在密歇根大学-安阿伯开始，从那时起每年都在中西部的各个大学举行会议。中西部DNA修复研讨会最初被设想为一个论坛，每年汇集来自中西部地区的DNA修复研究人员，讨论正在进行的研究，并促进合作。AMDRS的其他目标包括尽可能降低参加专题讨论会的费用，并优先让年轻的研究人员、博士后研究员和研究生在口头和海报会议上介绍他们的工作。DNA修复是维持基因组完整性和人类健康的基本细胞过程。DNA修复功能障碍与许多遗传性疾病以及慢性疾病如神经变性、心血管疾病、衰老和癌症有关。调查人员感到高兴的是，这一系列专题讨论会非常成功，过去几年出席人数大幅增加。成功的一个关键是保持低成本的出席。之所以能够实现这种低成本，是因为每年的组织者都在其所在机构举行研讨会，并获得了校内和校外的资金，以支付一些主要费用。特别是在资金有限的时候，AMDRS是一个会议，PI能够让他们的学生和博士后研究员与该领域的领先科学家互动，并在同行中介绍他们的工作。AMDRS现已进入第二个十年，并已开始回收。2010年，AMDRS将重返路易斯维尔。AMDRS的三个主要目标是：1）为主要来自中西部各州的科学家提供一个场所，介绍和讨论DNA损伤，修复和诱变领域的当前研究，并提供促进科学合作的机会。(2)为学生，博士后研究员，并开始独立调查的机会，以表达他们的工作，以同行和在该领域的领导者进行互动。(3)通过保持这些研讨会的可负担性来提供它们的特殊价值。 公共卫生相关性：引起DNA损伤的环境因子有助于慢性人类疾病的发展和进展，包括癌症、心血管和神经退行性疾病。DNA修复是一个重要的细胞过程，可以消除DNA损伤，有效的DNA修复对于预防这些慢性疾病至关重要。本次研讨会将汇集DNA修复研究人员讨论他们的最新研究，交流思想和发展新的合作。