12th Annual Midwest DNA Repair Symposium

第12届年度中西部DNA修复研讨会（AMDRS）将于2010年5月15日至16日在肯塔基州路易斯维尔市路易斯维尔大学谢尔比校区举行。AMDRS于1999年在密歇根大学安娜堡分校成立，此后每年在中西部的多所大学举行会议。中西部DNA修复研讨会最初被设想为一个论坛，每年将中西部地区的DNA修复研究人员聚集在一起，讨论正在进行的研究并促进合作。AMDRS的其他目标包括使参加研讨会的费用尽可能便宜，并为年轻的研究人员、博士后和研究生提供优先在口头和海报会议上展示他们的工作的机会。DNA修复是一个基本的细胞过程，对维持基因组完整性和人类健康至关重要。DNA修复功能障碍与许多遗传性疾病以及神经退行性疾病、心血管疾病、衰老和癌症等慢性疾病有关。研究人员很高兴这个系列专题讨论会非常成功，并且在过去几年中出席人数显著增加。成功的一个关键是保持了较低的出勤成本。如此低的费用之所以成为可能，是因为组织者每年都在其本国机构举办研讨会，并获得了校内和校外资金来支付一些主要费用。特别是在资金有限的情况下，AMDRS是一个PI能够带他们的学生和博士后研究员与该领域的顶尖科学家互动并在同行中展示他们的工作的会议。AMDRS现已进入第二个十年，并已开始回收利用。2010年，AMDRS将返回路易斯维尔。AMDRS的三个主要目标是：1)为主要来自中西部各州的科学家提供一个场所，展示和讨论DNA损伤、修复和突变领域的当前研究，并提供促进科学合作的机会。(2)为学生、博士后和刚开始独立研究的人提供机会，向同行展示他们的工作，并与该领域的领导者进行互动。(3)提供这些研讨会的特殊价值，保持他们负担得起。

DESCRIPTION (provided by applicant): The 12th Annual Midwest DNA Repair Symposium (AMDRS) will take place in Louisville, KY on May 15 - 16, 2010 at the Shelby Campus of the University of Louisville. The AMDRS started in 1999 at the University of Michigan - Ann Arbor and has met at various universities in the Midwest every year since then. The Midwest DNA Repair Symposium was originally conceived as a forum to bring together DNA repair researchers from the Midwestern region on an annual basis to discuss ongoing research and to stimulate collaborations. Additional goals of the AMDRS include making the cost of attending the symposium as inexpensive as possible and to provide young investigators, postdoctoral fellows and graduate students priority in presenting their work in oral and poster sessions. DNA repair is a fundamental cellular process critical to maintenance of genome integrity and human health. DNA repair dysfunction has been linked with many inherited diseases as well as chronic diseases such as neurodegeneration, cardiovascular disease, aging and cancer. The investigators are pleased that this symposia series has been very successful and has seen significant increase in attendance the past several years. One key to the success has been to keep the costs of attendance low. This low cost has been possible because the organizers for each year held the symposium at their home institutions and have secured both intramural and extramural funding to cover some of the major expenses. Especially in times of restricted funding, the AMDRS is one meeting to which PI's have been able to bring their students and post-doctoral fellows to interact with leading scientists in the field and to present their work among peers. The AMDRS is now in its second decade and has started to recycle. In 2010, the AMDRS is returning to Louisville. The three principle goals of the AMDRS: 1) to provide a venue for scientists mainly from the Midwestern states, to present and discuss current research in the field of DNA damage, repair and mutagenesis, and to provide opportunities to foster scientific collaborations. (2) To provide students, postdoctoral fellows, and beginning independent investigators the opportunity to p resent their work to peers and to interact with leaders in the field. (3) To provide an exceptional value of these symposia by keeping them affordable. PUBLIC HEALTH RELEVANCE: Environmental agents that cause DNA damage contribute to the development and progression of chronic human disease including cancer, and cardiovascular and neurodegenerative diseases. DNA repair is an essential cellular processes that removes the DNA damage and efficient DNA repair is essential to prevention of these chronic diseases. This symposium will bring together DNA repair researchers to discuss their newest research, to exchange ideas and to develop new collaborations.