Collaborative Human Tissue Network (CHTN)
协作人体组织网络 (CHTN)
基本信息
- 批准号:8668616
- 负责人:
- 金额:$ 83.81万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2014
- 资助国家:美国
- 起止时间:2014-04-16 至 2019-03-31
- 项目状态:已结题
- 来源:
- 关键词:AdvocateAlgorithmsAmericanBasic ScienceBenignBiocompatible MaterialsBiological PreservationBlast CellCancer CenterCancer HospitalClinicClinical DataCollaborationsCollectionCommunitiesComprehensive Cancer CenterComputer softwareConsultConsultationsDNADataDevelopmentDoctor of MedicineEpigenetic ProcessEquipment and supply inventoriesFutureGenomicsGuidelinesGynecologicHeadHealthHistologyHumanImage AnalysisIndividualInstitutesInstitutionInstitutional Review BoardsInternationalInternetIntranetInvestigationLaboratoriesLaboratory ResearchLettersLinkMailsMaintenanceMalignant - descriptorMalignant NeoplasmsManualsMedical centerMetricMorphologyNational Cancer InstituteNormal tissue morphologyOhioOnline SystemsOralParticipantPathologistPathologyPatientsPremalignantPrincipal InvestigatorProcessProductivityProteomicsProtocols documentationPublicationsQualifyingRNA analysisResearchResearch InstituteResearch PersonnelResource SharingResourcesRiskSamplingScienceSecureServicesShippingShipsSpecific qualifier valueSpecimenSupport GroupsSystemTechniquesTelephoneTestingTimeTissue ProcurementsTissue SampleTissuesTrainingTranslational ResearchUniversitiesUniversity HospitalsUpdateWorkabstractinganticancer researchbasecancer carecancer therapydiagnosis qualitydigitaldigital imagingexperiencehuman tissueimprovedinfection related cancerinterestmeetingsmemberopen sourceoperationpostersprogramsprospectiveprotocol developmentsuccesssymposiumtissue resourcetooltreatment strategyweb site
项目摘要
DESCRIPTION (provided by applicant): This proposal organizes the considerable resources and experience of Ohio Comprehensive Cancer Centers (CCC) in consortium to make available pathology remnant biomaterials for basic and early translational cancer research through the National Cancer Institute (NCI) Collaborative Human Tissue Network (CHTN). Aim 1. To provide prospectively procured, investigator-defined, high quality remnant pre-malignant, malignant, benign, diseased and normal biospecimens with associated demographic data to the scientific community in consortium with the Case Comprehensive Cancer Center, Case Western Reserve University; Seidman Cancer Center, University Hospitals, Case Medical Center; Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH and The Ohio State University Comprehensive Cancer Center (OSU-CCC), The Arthur G. James Cancer Hospital & Richard J. Solove Research Institute, Columbus, OH. This Ohio consortium has worked together since 2001 and has demonstrated biospecimen and associated data availability to respond to investigator requests. Aim 2. To provide individual consultation and laboratory services to interested investigators or investigators in need of assistance at any time during their research protocol development and project deployment. Dedicated pathologists are available to consult with potential investigators regarding research needs and OSU has an organized Human Tissue Resource Network (HTRN) with a biospecimen procurement program headed by pathologist, Leona W. Ayers, M.D., for research consultation and the HTRN organized network of research services and laboratories to work with investigators from application approval to receipt of requested biomaterials (http://htrn.osu.edu). Routine histology and special research services such as digital imaging, digital morphometric analysis, RNA/DNA isolation and TMAs are available. Aim 3. To contribute to biospecimen science and biospecimen research management to increase the quality and productivity of biospecimen use in research. Dr. Ayers and staff regularly attend biospecimen professional meetings and have contributed 18 abstracts, poster and podium presentations, at recent biospecimen and cancer focused national and international meetings. Aim 4. To work with the national CHTN and NCI program officers to harmonize the CHTN organization, to develop CHTN group projects, to improve shared IT resources and to educate the investigator and lay communities about CHTN resources. Our proposal has well qualified participants to serve on CHTN committees and subcommittees, contribute to the professional development of the CHTN and to provide an advocate to serve lay community interests.
描述(由申请人提供):这项提案组织了俄亥俄州综合癌症中心(CCC)在财团中的大量资源和经验,通过国家癌症研究所(NCI)协作人体组织网络(CHTN)为基础和早期转化性癌症研究提供病理残留生物材料。目的1.与凯斯西储大学凯斯综合癌症中心、塞德曼癌症中心、大学医院、凯斯医学中心、陶西格癌症研究所、克利夫兰诊所、俄亥俄州克利夫兰诊所和俄亥俄州立大学综合癌症中心(OSU-CCC)、亚瑟·G·詹姆斯癌症医院和理查德·J·索洛夫研究所(哥伦布,俄亥俄州)组成的联盟,向科学界提供前瞻性采购的、研究人员定义的、高质量的癌前、恶性、良性、疾病和正常生物标本以及相关的人口学数据。这个俄亥俄州联盟自2001年以来一直在合作,并展示了生物检疫技术和相关数据的可用性,以响应调查人员的请求。目标2.在研究方案制定和项目部署期间,随时向感兴趣的调查人员或需要协助的调查人员提供个别咨询和实验室服务。专门的病理学家可以就研究需要咨询潜在的研究人员,俄亥俄州立大学有一个有组织的人类组织资源网络,其中有一个由病理学家利昂娜·W·艾尔斯医学博士领导的生物标本采购计划,用于研究咨询,该组织资源网络组织了研究服务和实验室网络,从申请批准到收到请求的生物材料(http://htrn.osu.edu).)与研究人员合作提供常规组织学和特殊研究服务,如数字成像、数字形态测量分析、RNA/DNA分离和TMAS。目的3.促进生物谱学和生物谱系研究管理,提高生物谱系研究的质量和生产率。艾尔斯博士和工作人员定期参加生物医学专业会议,并在最近以生物医学和癌症为重点的国内和国际会议上发表了18篇摘要、海报和讲台演讲。目的4.与国家CHTN和NCI项目官员合作,协调CHTN组织,发展CHTN小组项目,改善共享的IT资源,并对研究人员和普通社区进行关于CHTN资源的教育。我们的建议有很好的合格参与者在CHTN委员会和小组委员会服务,为CHTN的专业发展做出贡献,并为服务于非专业社区的利益提供倡导者。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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LEONA W AYERS其他文献
LEONA W AYERS的其他文献
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{{ truncateString('LEONA W AYERS', 18)}}的其他基金
COOPERATIVE TISSUE BANK OF HIV POSITIVE MALIGNANCIES
HIV 阳性恶性肿瘤合作组织库
- 批准号:
7441181 - 财政年份:1998
- 资助金额:
$ 83.81万 - 项目类别:
COOPERATIVE TISSUE BANK OF HIV POSITIVE MALIGNANCIES
HIV 阳性恶性肿瘤合作组织库
- 批准号:
7067158 - 财政年份:1998
- 资助金额:
$ 83.81万 - 项目类别:
Mid-Region AIDS and Cancer Specimen Resource Consortium
中部地区艾滋病和癌症标本资源联盟
- 批准号:
7687968 - 财政年份:1998
- 资助金额:
$ 83.81万 - 项目类别:
COOPERATIVE TISSUE BANK OF HIV POSITIVE MALIGNANCIES
HIV 阳性恶性肿瘤合作组织库
- 批准号:
6376132 - 财政年份:1998
- 资助金额:
$ 83.81万 - 项目类别:
COOPERATIVE TISSUE BANK OF HIV POSITIVE MALIGNANCIES
HIV 阳性恶性肿瘤合作组织库
- 批准号:
7124925 - 财政年份:1998
- 资助金额:
$ 83.81万 - 项目类别:
COOPERATIVE TISSUE BANK OF HIV POSITIVE MALIGNANCIES
HIV 阳性恶性肿瘤合作组织库
- 批准号:
7496266 - 财政年份:1998
- 资助金额:
$ 83.81万 - 项目类别:
COOPERATIVE TISSUE BANK OF HIV POSITIVE MALIGNANCIES
HIV 阳性恶性肿瘤合作组织库
- 批准号:
2895236 - 财政年份:1998
- 资助金额:
$ 83.81万 - 项目类别:
COOPERATIVE TISSUE BANK OF HIV POSITIVE MALIGNANCIES
HIV 阳性恶性肿瘤合作组织库
- 批准号:
6654445 - 财政年份:1998
- 资助金额:
$ 83.81万 - 项目类别:
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