Research Training Program in Environmental Pediatrics

环境儿科研究培训计划

• 批准号: 8846624
• 负责人: Robert O Wright
• 金额: $ 35.1万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8846624
• 关键词: Pediatrics; Research Training; Training Programs

DESCRIPTION (provided by applicant): Children today are at risk of exposure to multiple environmental hazards - toxic chemicals, social stressors and the hazards of the built environment. A growing body of research indicates that environmental exposures contribute to common pediatric diseases: asthma, neurodevelopmental disorders, birth defects, obesity and type 2 diabetes and possibly also to disease in adult life. Yet few pediatricians are trained to study, diagnose, treat or prevent diseases of environmental origin, and few academic health centers have research leaders or programs in environmental pediatrics. The IOM states that there is national need to expand the scientific workforce in environmental medicine. To train the next generation of physician-scientists and academic leaders in environmental pediatrics, the Mount Sinai School of Medicine seeks renewal of its 3-year, interdisciplinary, post-residency/post-doctoral research training program in environmental pediatrics that began in 2007. Epidemiological research in environmental pediatrics is the core training theme. Two new fellows are admitted each year. Selection is competitive, and fellows are a mix of clinically trained pediatricians and doctorally trained research scientists. Emphasis is placed on recruitment of underrepresented minorities. We provide fellows with a robust methodological base and equip them with a versatile set of tools they can apply to study a wide range of scientific questions. The focus in year 1 is on education in epidemiology, biostatistics, toxicology, environmental medicine and research design to fulfill requirements for an MPH degree. In years 2 and 3, emphasis is on mentored research that generates an MPH thesis, produces manuscripts and posters, and fosters transition toward independence. Each fellow is guided by a mentor and advisors from multiple clinical and basic science departments. Courses are provided in grant-writing and responsible conduct of research. For physicians, supervised clinical experience in environmental pediatrics extends throughout the fellowship. Formal evaluation of each fellow is conducted semi-annually. An Executive Faculty Committee and an External Advisory Board have been formed. Expected outcomes include: authorship of 1-2 publishable manuscripts based on original research; authorship of 2-3 posters; completion of an MPH focused on environmental pediatrics; development in year 3 of a K08 or R01 grant proposal; and evidence of transition toward independent investigator status. This program builds on a fellowship in environmental pediatrics supported at Mount Sinai in 2002-2007 by the Academic Pediatric Association. It links to a Breast Cancer and Environment Research Center, a Pediatric Environmental Health Specialty Unit, and the Queens Vanguard Center of the National Children's Study (NCS). The program has successfully recruited 10 fellows and graduated 4. All 4 graduates are pursuing academic careers in environmental pediatrics. Fellows and graduates have published over 30 papers. One graduate is a Lead Investigator in the NCS. Another has secured an NIH K99 award.

描述(申请人提供)：今天的儿童面临着暴露在多种环境危害中的风险--有毒化学品、社会应激源和建筑环境的危害。越来越多的研究表明，环境暴露会导致常见的儿科疾病：哮喘、神经发育障碍、出生缺陷、肥胖和2型糖尿病，也可能导致成年后的疾病。然而，很少有儿科医生接受过研究、诊断、治疗或预防环境引起的疾病的培训，也没有几个学术卫生中心拥有环境儿科的研究带头人或项目。国际移民组织表示，有必要在全国范围内扩大环境医学的科研队伍。为了培养下一代环境儿科学的内科科学家和学术领袖，西奈山医学院寻求更新其始于2007年的为期3年的环境儿科学跨学科、住院医师/博士后研究后培训计划。环境儿科流行病学研究是培训的核心主题。每年招收两名新学员。遴选是竞争的，研究员是受过临床训练的儿科医生和受过博士训练的研究科学家的混合体。重点是招募任职人数不足的少数群体。我们为研究员提供了强大的方法论基础，并为他们配备了一套通用的工具，他们可以应用于研究广泛的科学问题。第一年的重点是流行病学、生物统计学、毒理学、环境医学和研究设计方面的教育，以满足公共卫生硕士学位的要求。在第二年和第三年，重点是指导研究，产生公共卫生硕士论文，制作手稿和海报，并促进向独立的过渡。每个研究员由来自多个临床和基础科学系的一名导师和顾问指导。课程内容包括拨款撰写和负责任的研究工作。对于内科医生来说，在环境儿科方面的临床指导经验贯穿于整个团契。对每个研究员的正式评估每半年进行一次。已经成立了一个执行学院委员会和一个外部咨询委员会。预期结果包括：基于原始研究的1-2篇可发表手稿的作者；2-3张海报的作者身份；完成专注于环境儿科的公共卫生硕士学位；在第三年制定K08或R01拨款提案；以及向独立研究员身份过渡的证据。该计划建立在2002-2007年间由学术儿科协会在西奈山支持的环境儿科研究奖学金的基础上。它连接到乳腺癌和环境研究中心、儿科环境健康专科单位和国家儿童研究(NCS)的皇后区先锋中心。该项目已经成功招募了10名研究员，并毕业了4名。所有4名毕业生都在追求环境儿科的学术生涯。院士和毕业生发表了30多篇论文。一名毕业生是NCS的首席研究员。另一位则获得了NIH K99奖。