Molecular, Cellular, and Animal Models Core
Molecular, Cellular, and Animal Models Core
批准号:
9077588
负责人:
Anton M Bennett
金额:
$26.73万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
未结题
起止时间:
2001-05-01 至
关键词:
AdenovirusesAnimal ModelBreedingCalciumCell modelCellular biologyChronicCommunitiesDevelopmentGenerationsGenotypeGoalsHepatocyteHuman ResourcesIndividualInstitutionLaboratoriesLiverLiver diseasesMaintenanceMitogen-Activated Protein KinasesMolecular BiologyMolecular ModelsMusPhosphoric Monoester HydrolasesPlasmid Cloning VectorPlasmidsProtocols documentationReagentRegulationServicesSignal TransductionSmall Interfering RNASourceStandardizationSubfamily lentivirinaeTechniquesabstractingliver injurymolecular modelingmouse modelprogramsrepositoryresponse
中文摘要
摘要/摘要:
分子、细胞和动物模型核心(核心B)将提供试剂以协助
肝脏中钙、InsP3R、MAP激酶/磷酸酶和OGT信号转导的研究其核心是
将协助开发和鉴定表达载体、siRNA和慢病毒
按要求在各个项目中使用的构造。核心将作为一个中心
四个项目产生的所有试剂的储存库,并协助将其分发到
该机构以外的其他实验室。核心将包括专职人员,并将
位于主任实验室内。
英文摘要
Summary/Abstract:
The Molecular, Cellular and Animal Model Core (Core B) will provide reagents to assist in the
study of calcium, InsP3R, MAP kinases/phosphatases and OGT signaling in the liver. The core
will assist in the development and characterization of expression plasmids, siRNA and lentiviral
constructs as requested for use in the individual projects. The core will serve as a central
repository for all the reagents generated by the four projects and assist in their distribution to
other laboratories outside of the institution. The core will include dedicated personnel and will be
located within the Director's laboratory.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
MKP5 allostery in MAPK regulation and signaling in the heart
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批准号:10552036
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项目类别:
-
资助金额:$60.48万
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财政年份:2022
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负责人:Anton M Bennett
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依托单位:
MKP5 allostery in MAPK regulation and signaling in the heart
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批准号:10375784
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项目类别:
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资助金额:$62.03万
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财政年份:2022
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负责人:Anton M Bennett
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依托单位:
Dual-specificity phosphatase action in muscle disease
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批准号:10621754
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项目类别:
-
资助金额:$52.93万
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财政年份:2022
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负责人:Anton M Bennett
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依托单位:
Dual-specificity phosphatase action in muscle disease
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批准号:10342959
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项目类别:
-
资助金额:$52.47万
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财政年份:2022
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负责人:Anton M Bennett
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依托单位:
Yale Post-Baccalaureate Research Education Program
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批准号:10686863
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项目类别:
-
资助金额:$31.6万
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财政年份:2021
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负责人:Anton M Bennett
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依托单位:
Yale Post-Baccalaureate Research Education Program
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批准号:10474267
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项目类别:
-
资助金额:$26.07万
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财政年份:2021
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负责人:Anton M Bennett
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依托单位:
Yale Post-Baccalaureate Research Education Program
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批准号:10113213
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项目类别:
-
资助金额:$26.07万
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财政年份:2021
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负责人:Anton M Bennett
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依托单位:
Signaling by Shp2 mutants in RASopathies
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批准号:9889163
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项目类别:
-
资助金额:$56.13万
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财政年份:2018
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负责人:Anton M Bennett
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依托单位:
MKP5 in Dystrophic Muscle Disease
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批准号:9003031
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项目类别:
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资助金额:$38.78万
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财政年份:2015
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负责人:Anton M Bennett
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依托单位:
MKP5 in Dystrophic Muscle Disease
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批准号:8839100
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项目类别:
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资助金额:$40.34万
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财政年份:2015
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负责人:Anton M Bennett
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依托单位:
Signaling by gain-of-function SHP-2 mutants in Noonan syndrome
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批准号:8622206
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项目类别:
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资助金额:$36.69万
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财政年份:2012
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负责人:Anton M Bennett
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依托单位:
Signaling by gain-of-function SHP-2 mutants in Noonan syndrome
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批准号:8457111
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项目类别:
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资助金额:$35.42万
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财政年份:2012
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负责人:Anton M Bennett
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依托单位:
Signaling by gain-of-function SHP-2 mutants in Noonan syndrome
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批准号:8217486
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项目类别:
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资助金额:$36.5万
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财政年份:2012
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负责人:Anton M Bennett
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依托单位:
FASEB Summer Conference on Protein Phosphatases
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批准号:8092861
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项目类别:
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资助金额:$0.4万
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财政年份:2008
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负责人:Anton M Bennett
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依托单位:
FASEB Summer Conference on Protein Phosphatases
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批准号:7644362
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项目类别:
-
资助金额:$0.6万
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财政年份:2008
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负责人:Anton M Bennett
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依托单位:
Mechanisms of Metabolic Control by MKP-1
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批准号:7644495
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项目类别:
-
资助金额:$33.12万
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财政年份:2007
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负责人:Anton M Bennett
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依托单位:
CORE--MOLECULAR AND CELL BIOLOGY
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批准号:7424052
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项目类别:
-
资助金额:$16.17万
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财政年份:2007
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负责人:Anton M Bennett
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依托单位:
Mechanisms of Metabolic Control by MKP-1
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批准号:7323137
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项目类别:
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资助金额:$33.33万
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财政年份:2007
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负责人:Anton M Bennett
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依托单位:
Mechanisms of Metabolic Control by MKP-1
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批准号:8098163
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项目类别:
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资助金额:$32.47万
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财政年份:2007
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负责人:Anton M Bennett
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依托单位:
REGULATION OF LIVER FUNCTION BY MAPK/MKP-1
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批准号:7424051
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项目类别:
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资助金额:$20.15万
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财政年份:2007
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负责人:Anton M Bennett
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依托单位:
海外基金