Molecular, Cellular, and Animal Models Core

分子、细胞和动物模型核心

• 批准号: 9077588
• 负责人: Anton M Bennett
• 金额: $ 26.73万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9077588
• 关键词: Adenoviruses; Animal Model; Breeding; Calcium; Cell model; Cellular biology; Chronic; Communities; Development; Generations; Genotype; Goals; Hepatocyte; Human Resources; Individual; Institution; Laboratories; Liver; Liver diseases; Maintenance; Mitogen-Activated Protein Kinases; Molecular Biology; Molecular Models; Mus; Phosphoric Monoester Hydrolases; Plasmid Cloning Vector; Plasmids; Protocols documentation; Reagent; Regulation; Services; Signal Transduction; Small Interfering RNA; Source; Standardization; Subfamily lentivirinae; Techniques; abstracting; liver injury; molecular modeling; mouse model; programs; repository; response

Summary/Abstract: The Molecular, Cellular and Animal Model Core (Core B) will provide reagents to assist in the study of calcium, InsP3R, MAP kinases/phosphatases and OGT signaling in the liver. The core will assist in the development and characterization of expression plasmids, siRNA and lentiviral constructs as requested for use in the individual projects. The core will serve as a central repository for all the reagents generated by the four projects and assist in their distribution to other laboratories outside of the institution. The core will include dedicated personnel and will be located within the Director's laboratory.

摘要/文摘: