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REPOSITORY PULLS FOR VARIABILITY OF NON-PERSISTENT CHEMICALS ACROSS SENSITIVE WINDOWS - LIFE STUDY

REPOSITORY PULLS FOR VARIABILITY OF NON-PERSISTENT CHEMICALS ACROSS SENSITIVE WINDOWS - LIFE STUDY
存储库拉动敏感窗口中非持久性化学品的可变性 - 生命研究
批准号：
9348701
负责人：
OGUZ MANDACI
金额：
$0.75万
依托单位：
FISHER BIOSERVICES, INC.
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
项目状态：
已结题
起止时间：
2014-09-23 至 2024-09-22
来源：
https://reporter.nih.gov/project-details/9348701
关键词：
Biological AssayChemicalsCollectionConceptionsContractsCountryCouplesEndocrine DisruptorsEnrollmentEnsureEnvironmentExposure toFertilityGeographic LocationsHumanInvestigationMichiganPregnancyRecruitment ActivityRefrigerationReportingResidual stateSafetySamplingSecureShippingShipsSpecimenSystemTexasTransportationUrineWomanenvironmental chemicalpregnantrepository

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中文摘要
翻译
人类生物标本样本将从生育力和环境纵向调查（LIFE）研究运送至DIPHR签约的环境化学测定实验室。LIFE研究招募了来自密歇根州和德克萨斯州16个国家的501对夫妇，这些夫妇代表了据报道接触过内分泌干扰化学品的地理区域。首次尿液采集发生在入组时（基线），并在下一个月从每对夫妇的伴侣处重复采集尿液样本。第三个样本是从怀孕或尝试6个月未怀孕的女性中收集的。本项特定研究将使用在围受孕期和妊娠早期时间窗内采集的尚未测量的尿液样本。
英文摘要
Human biospecimen samples will be shipped from the Longitudinal Investigation of Fertility and Environment (LIFE) study to DIPHR-contracted environmental chemical assay lab. The LIFE study recruited 501 couples from 16 countries in Michigan and Texas, representing geographic areas with reported exposures to endocrine disrupting chemicals. The initial urine collection occurred upon enrollment (baseline) with a repeated urine sample obtained from both partners of each couple the following month. A third sample was collected from women upon becoming pregnant or after 6 months of trying without pregnancy. This specific study will utilize the as yet unmeasured urine samples that were collected during the peri-conception and early pregnancy windows.
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  • 项目类别：
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  • 财政年份：
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