Delaware INBRE

这第三个特拉华州INBRE更新提案的目标是采取另一个重大步骤，以改善 通过扩大DE-INBRE正在进行的工作，在全州范围内建立一个生物医学 研究能力。该项目将继续加强研究专门知识和基础设施， DE-INBRE学术和临床合作机构-特拉华州特拉华州大学 大学、特拉华州技术社区学院、韦斯利学院、克里斯蒂娜护理卫生系统和 Nemours/A.I.杜邦儿童医院 除了不断增长的全州生物信息学计划，三个生物医学研究主题将是 通过发展研究项目进行：这些项目将侧重于癌症，心血管疾病， 疾病和神经科学。基金提供支持初级教师，博士后和研究生 学生参与每个研究主题内的指导研究项目。研究主题是 由目前INBRE下开发的全州生物医学基础设施支持，但 大大增强了生物信息学和集中化，仪器核心。教育和 专业发展核心将为来自该州的学生提供参与研究的机会。 本科院校和社区学院，从而发展学生追求的管道 在医疗保健行业的职业生涯和提高国家的劳动力的生物医学知识。 DE-INBRE-3提案的具体目标是：（1）建立一个全州范围的网络， 特拉华州可持续的生物医学研究能力;（2）发展独立和相互依赖的 在网络中蓬勃发展的研究人员和机构;（3）通过以下方式将DE-INBRE倡议制度化 将项目过渡到伙伴机构;（4）加强生物医学科学和技术 了解国家的劳动力。 本提案中描述的五个DE-INBRE核心部分-生物信息学核心;发展研究 项目计划;集中研究仪器核心;教育和专业发展 核心;以及改建和翻修核心-将得到有效的行政核心的支持。 这项更新提案将为继续建设生物医学研究基础设施提供关键资金 需要发展目前的计划，以提高特拉华州的可持续研究能力， 对该州及其机构的经济以及特拉华州公民的健康产生重大影响。

The goal of this third Delaware INBRE renewal proposal is to take another major step towards improving health care in the State by extending the ongoing work of the DE-INBRE in building a statewide biomedical research capability. The project will continue to strengthen the research expertise and infrastructure of the DE-INBRE academic and clinical partner institutions - the University of Delaware, Delaware State University, Delaware Technical Community College, Wesley College, Christiana Care Health System and Nemours/A.I. duPont Hospital for Children. In addition to a growing statewide bioinformatics program, three biomedical Research Themes will be pursued through developmental research projects: these programs will focus on cancer, cardiovascular disease and neurosciences. Funds are provided to support junior faculty, postdoctoral and graduate students engaged in mentored research projects within each Research Theme. The Research Themes are supported by a statewide biomedical infrastructure developed under the current INBRE, but with considerably enhanced Bioinformatics and Centralized, Instrumentation Cores. An Education and Professional Development Core will provide engaging research opportunities for students from the state's undergraduate institutions and community colleges, thereby developing a pipeline of students pursuing careers in the health care industry and enhancing the biomedical knowledge of the state's workforce. The Specific Aims of the DE-INBRE-3 proposal are to: (1) Foster a statewide Network to create a strong, sustainable biomedical research capability in Delaware; (2) Develop independent and inter-dependent researchers and institutions that thrive within the Network; (3) Institutionalize DE-INBRE initiatives by transitioning programs into the partner institutions; and (4) Enhance the biomedical science and technology knowledge of the state's workforce. The five DE-INBRE Core Sections described in this proposal - Bioinformatics Core; Developmental Research Project Program; Centralized Research Instrumentation Core; Education and Professional Development Core; and Alterations and Renovations Core - will be supported by an effective Administrative Core. This renewal proposal will provide critical funding to continue building biomedical research infrastructure needed to develop the current programs toward a sustainable research capability in Delaware that will have significant impact on the economy of the state and its institutions and the health of Delaware's citizens.