Research conference titled "Building and Crossing the Translational Bridge in Alopecia Areata"
Research conference titled "Building and Crossing the Translational Bridge in Alopecia Areata"
批准号:
9261194
负责人:
Angela M Christiano
金额:
$1.5万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-09-12 至 2017-08-31
关键词:
AffectAgeAlopecia AreataAmericanAnimal ModelAutoimmune DiseasesAutoimmune ProcessBiological ProductsCollaborationsConsensusDermatologicDevelopmentDisabled PersonsDiscriminationDiseaseDoctor of PhilosophyEmotionalEthnic OriginFDA approvedFoundationsGeneticGoalsGovernment AgenciesHairHeadImaging TechniquesImmunologyIndustryLearningLifeLife ExpectancyMassachusettsMedicalMinnesotaNational Institute of Arthritis and Musculoskeletal and Skin DiseasesOccupationsPainParticipantPatient-Focused OutcomesPatientsPopulationProsthesisPublic HealthPublished CommentRaceResearchResearch PersonnelResearch PriorityResearch Project GrantsSchoolsSeasonsSenior ScientistUnited States National Institutes of HealthUniversitiesVoiceWomanbullyingcareerclinical investigationdesigndisabilitydrug developmentethnic minority populationimprovedinnovationmeetingsracial minorityskin disorderskin microbiomesymposium
中文摘要
点击翻译按钮获取中文摘要
英文摘要
PROJECT SUMMARY/ABSTRACT:
This research meeting ‐‐ “Building and Crossing the Translational Bridge in Alopecia Areata” ‐‐ is
designed to share findings and distill learning from the most current research advances and set
strategic research priorities for the next two to five years to hasten progress in finding a viable,
accessible treatment for this autoimmune skin disease that affects 2.1% of the population.
Alopecia areata is a disease characterized by hair loss and emotional pain that affects 6.6 million
Americans of all ages, races and ethnicities. There are no treatments approved by the FDA for this
common disfiguring disease. Although alopecia areata does not reduce life expectancy, it is a
disability that results in unfair discrimination, like being bullied for looking different, expelled from
school for wearing a hat to keep the head warm or being fired from a job at a hotel for wearing a
headscarf because a hair prosthesis was prohibitively expensive. These are true and recent stories.
This two‐day meeting designed to blend concise informative presentations about the newest
developments with meaningful discussion among established senior scientists, new investigators and
patients who stand to benefit will be led by three esteemed medical and scientific co‐chairs: Angela
Christiano, PhD, of Columbia University; Maria Hordinsky, MD, of the University of Minnesota; and,
John Harris, MD, PhD, of the University of Massachusetts Worcester. Proceedings will be held each
day with a patient and industry roundtable dinner between. Presentations of 10‐15 minutes will be
followed by lengthy Q&A sessions designed to foment substantive discussion. The conference will
conclude with consensus‐building about priorities for research in the next two years and beyond.
Progress on research goals set at the 2014 summit which was supported by NIAMS and NCATS will
be reviewed, including specific advances in genetics, immunology, animal models, imaging
techniques and clinical investigation. New developments spearheaded through projects supported by
the NIH ‐‐ in cross‐cutting autoimmune and dermatologic research, immunology of the skin and
microbiome ‐‐ as well as identification of targets and new collaborations with biopharmaceutical
companies will be reviewed. Presentations on patient‐centered outcomes will also be included.
The goals of the meeting are to: efficiently generate rapid progress for alopecia areata research;
strengthen ties and increase understanding and benefit between alopecia areata researchers and those
focused on related skin and autoimmune diseases; improve partnerships with key government
agencies; spark innovation and collaboration; and set priorities which will inform research grant‐
making by the National Alopecia Areata Foundation and other funders of alopecia areata research.
期刊论文(14)
专著(0)
科研奖励(0)
会议论文
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DOI:
10.1016/j.jisp.2017.10.013
发表时间:
2018-01-01
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[Cervantes, Jessica, Jimenez, Joaquin J, Tosti, Antonella]
通讯作者:
Tosti, Antonella
DOI:
10.1016/j.jisp.2017.10.012
发表时间:
2018-01-01
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[Atanaskova Mesinkovska, Natasha]
通讯作者:
Atanaskova Mesinkovska, Natasha
Large-Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata.
大规模表位鉴定筛选及其在斑秃研究中的潜在应用。
DOI:
10.1016/j.jisp.2017.10.001
发表时间:
2018
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[LindestamArlehamn,CeciliaS, Paul,Sinu, ChunWang,EddyHsi, deJong,Annemieke, Christiano,AngelaM, Sette,Alessandro]
通讯作者:
Sette,Alessandro
DOI:
10.1016/j.jisp.2017.10.003
发表时间:
2018-01-01
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[Liu, Lucy Yichu, King, Brett Andrew]
通讯作者:
King, Brett Andrew
Building and Crossing the Translational Bridge: 2016 Alopecia Areata Research Summit Highlights.
构建并跨越转化桥梁:2016 年斑秃研究峰会亮点。
DOI:
10.1016/j.jisp.2017.10.004
发表时间:
2018
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[Kranz,Dory, Ellison,Abby, Mesinkovska,NatashaA, Christiano,AngelaM, Hordinsky,MariaK, Harris,JohnE]
通讯作者:
Harris,JohnE
共 12 条
Influence of the Microbiome on the Natural History of Alopecia Areata
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批准号:10585677
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项目类别:
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资助金额:$25.33万
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财政年份:2023
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负责人:Angela M Christiano
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Senescence-on-a-chip: Building a microphysiological 3D skin model
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批准号:10685382
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资助金额:$55.0万
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财政年份:2022
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负责人:Angela M Christiano
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依托单位:
Senescence-on-a-chip: Building a microphysiological 3D skin model
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批准号:10552430
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项目类别:
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资助金额:$55.0万
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财政年份:2022
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负责人:Angela M Christiano
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依托单位:
A Multi-scale Atlas of Senescence in Diverse Tissue Types
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批准号:10385184
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资助金额:$271.2万
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财政年份:2021
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依托单位:
A Multi-scale Atlas of Senescence in Diverse Tissue Types
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批准号:10683316
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项目类别:
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资助金额:$262.77万
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财政年份:2021
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负责人:Angela M Christiano
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依托单位:
Immunomonitoring and Microbiome Analysis in Alopecia Areata Patients Undergoing Fecal Microbiota Transplantation
-
批准号:10157320
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项目类别:
-
资助金额:$28.51万
-
财政年份:2021
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负责人:Angela M Christiano
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依托单位:
Immunomonitoring and Microbiome Analysis in Alopecia Areata Patients Undergoing Fecal Microbiota Transplantation
-
批准号:10392950
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项目类别:
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资助金额:$28.23万
-
财政年份:2021
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负责人:Angela M Christiano
-
依托单位:
Immunomonitoring and Microbiome Analysis in Alopecia Areata Patients Undergoing Fecal Microbiota Transplantation
-
批准号:10414461
-
项目类别:
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资助金额:$7.8万
-
财政年份:2021
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负责人:Angela M Christiano
-
依托单位:
Clinical Trials in a Dish Using a Personalized Multi-Tissue Platform for Atopic Dermatitis
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批准号:10038233
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项目类别:
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资助金额:$60.0万
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财政年份:2020
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负责人:Angela M Christiano
-
依托单位:
Drug Screening with a Biofrabricated 3-D Immunocompetent Skin Model for Drug Discovery in Psoriatic Disease
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批准号:10249327
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项目类别:
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资助金额:$64.12万
-
财政年份:2020
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负责人:Angela M Christiano
-
依托单位:
Bioprinting 3D skin for patient-specific drug discovery in inflammatory skin diseases.
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批准号:9571254
-
项目类别:
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资助金额:$63.88万
-
财政年份:2017
-
负责人:Angela M Christiano
-
依托单位:
Alopecia Areata Center for Research Translation (AACORT)
-
批准号:10091972
-
项目类别:
-
资助金额:$155.48万
-
财政年份:2016
-
负责人:Angela M Christiano
-
依托单位:
Project 1: Translational Science of Alopecia Areata
-
批准号:10091984
-
项目类别:
-
资助金额:$61.2万
-
财政年份:2016
-
负责人:Angela M Christiano
-
依托单位:
Alopecia Areata Center for Research Translation (AACORT)
-
批准号:9354175
-
项目类别:
-
资助金额:$165.59万
-
财政年份:2016
-
负责人:Angela M Christiano
-
依托单位:
Alopecia Areata Center for Research Translation (AACORT)
-
批准号:9194847
-
项目类别:
-
资助金额:$160.0万
-
财政年份:2016
-
负责人:Angela M Christiano
-
依托单位:
Administrative Core
-
批准号:10091977
-
项目类别:
-
资助金额:$38.67万
-
财政年份:2016
-
负责人:Angela M Christiano
-
依托单位:
9th World Congress for Hair Research (2015 WCHR)
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批准号:9178231
-
项目类别:
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资助金额:$0.75万
-
财政年份:2015
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负责人:Angela M Christiano
-
依托单位:
Functional Genomics of Alopecia Areata
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批准号:8810989
-
项目类别:
-
资助金额:$49.28万
-
财政年份:2015
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负责人:Angela M Christiano
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依托单位:
Functional Genomics of Alopecia Areata
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批准号:9521505
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项目类别:
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资助金额:$54.64万
-
财政年份:2015
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负责人:Angela M Christiano
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依托单位:
Developing an Alopecia Areata Disease Activity Index (ALADIN)
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批准号:9139417
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项目类别:
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资助金额:$21.12万
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财政年份:2014
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负责人:Angela M Christiano
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依托单位:
国内基金
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