Pathways to extensive and pan antibiotic resistance in the globally disseminated Acinetobacter baumannii GC2 clone

全球传播的鲍曼不动杆菌 GC2 克隆产生广泛和泛抗生素耐药性的途径

• 批准号: nhmrc : GNT1079616
• 负责人: Prof Ruth Hall
• 金额: $ 83.25万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/pathways-extensive-pan-gc2-clone/1345296
• 关键词: Pathways; extensive; pan; antibiotic; resistance

The project will study the evolution of a Acinetobacter baumannii clone that is found all around the world, and has become resistant to most or all of the currently available antibiotics. Resistance has been acquired in a series of steps, and the resistance genes present and the events involved will be used to understand the globalization process. The increased understanding of resistance development should assist in controlling untreatable infections and in preserving antibiotics.

该项目将研究一种鲍曼不动杆菌克隆的进化，这种克隆在世界各地都有发现，并且已经对目前可用的大多数或所有抗生素产生耐药性。抗性是通过一系列步骤获得的，抗性基因和所涉及的事件将用于理解全球化进程。增加对耐药性发展的了解应有助于控制无法治疗的感染和保护抗生素。