How insertion sequences mobilize antibiotic resistance genes

插入序列如何调动抗生素抗性基因

• 批准号: nhmrc : 1141540
• 负责人: Prof Ruth Hall
• 金额: $ 45.64万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/insertion-sequences-mobilize-resistance-genes/1319488
• 关键词: How; insertion; sequences; mobilize; antibiotic

Resistance to all antibiotics available for treatment of bacterial infections is a cause for global concern (Word Health Organization, US Centres for Disease Control) as it also compromises therapies relying on antibiotics such as transplantation and cancer chemotherapy. This project will seek to understand how resistance genes are recruited and disseminated into different types of bacteria that repeatedly spread around the world.

对所有可用于治疗细菌感染的抗生素的耐药性是全球关注的原因（世界卫生组织，美国疾病控制中心），因为它也损害了依赖抗生素的治疗，如移植和癌症化疗。该项目将试图了解耐药基因是如何被招募和传播到不同类型的细菌中的，这些细菌在世界各地反复传播。