Pathways to extensive and pan antibiotic resistance in the globally disseminated Acinetobacter baumannii GC2 clone

该项目将研究鲍曼不动杆菌克隆的进化，这种克隆在世界各地都有发现，并且已经对大多数或所有目前可用的抗生素具有耐药性。抗性是在一系列步骤中获得的，抗性基因的存在和所涉及的事件将被用来理解全球化进程。对耐药性发展的进一步了解应有助于控制无法治疗的感染和保存抗生素。

The project will study the evolution of a Acinetobacter baumannii clone that is found all around the world, and has become resistant to most or all of the currently available antibiotics. Resistance has been acquired in a series of steps, and the resistance genes present and the events involved will be used to understand the globalization process. The increased understanding of resistance development should assist in controlling untreatable infections and in preserving antibiotics.